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Adapalene 0.003 MG/MG / benzoyl peroxide 0.025 MG/MG Topical Gel — RxCUI 1663745

RxNorm drug concept · Semantic clinical drug
RxCUI 1663745 Semantic clinical drug · SCD ● Current RxNorm concept 11 FDA products 21 package NDCs Snapshot Jul 14, 2026

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Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI1663745
Official nameAdapalene 0.003 MG/MG / benzoyl peroxide 0.025 MG/MG Topical Gel
Concept typeSemantic clinical drug (SCD)
RxNorm statusCurrent RxNorm concept
Also known asadapalene 0.3 % / benzoyl peroxide 2.5 % Topical Gel
FDA products mapped11
Package NDCs mapped21
Reported Medicaid activity (SDUD)13,807 prescriptions · 24 state & territory Medicaid programs · latest period Q4 2025
RxNorm release07/06/2026
Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Benzoyl Peroxide Topical: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist
  • Benzoyl peroxide is most commonly used to treat acne — products like Oxy 10 and PanOxyl are available over the counter for this purpose. EPSOLAY, a prescription cream version, is s...
  • What exactly is benzoyl peroxide used for?
  • Yes, that's very common, especially when you're just starting out. Benzoyl peroxide can cause dryness, redness, peeling, and some burning or stinging. The best approach is to start...
  • My skin got really dry and red after I started using it — is that normal?
📖 Read our full Benzoyl Peroxide Topical guide →

🕸️ Concept Web — How Adapalene 0.003 MG/MG / benzoyl peroxide 0.025 M... Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.
This page's concept Adapalene 0.003 MG/MG / benzoyl peroxide 0.025 MG/MG Topical Gel RxCUI 1663745

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

  1. Ingredients 3

    The active substance itself — no strength, form, or brand attached yet.

    • Adapalene 60223
    • Benzoyl peroxide 1418
    • Adapalene / benzoyl peroxide 859393
  2. Brand names 1

    The same medicine's trade names. A brand name alone says nothing about strength or form.

    • Epiduo 830645
  3. Dose forms 6

    The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.

    • Adapalene / benzoyl peroxide Topical Gel 829538
    • Adapalene / benzoyl peroxide Topical Product 1163692
    • Adapalene / benzoyl peroxide Topical Gel [Epiduo] 830647
    • Epiduo Topical Product 1167609
    • Topical Gel 346286
    • Topical Product 1151122
  4. Clinical & branded drugs 4

    Ingredient + strength + dose form. These are the concepts real FDA products actually carry.

Showing up to 8 concepts per family — 14 of 14 stored related concepts drawn.
These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

  • Adapalene 0.003 MG/MG SCDC · 722110
  • Benzoyl peroxide 0.025 MG/MG SCDC · 340120
  • Adapalene / benzoyl peroxide Topical Gel SCDF · 829538
  • Adapalene / benzoyl peroxide Topical Product SCDG · 1163692

Brand-Name Concepts

📦 FDA Products & Package NDCs

11 products · 21 package NDCs
21 package NDCs map to RxCUI 1663745 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.
Package NDC Package Brand / generic name Labeler Marketing start
00299-5906-00 2 g in 1 TUBE (0299-5906-00) epiduo forte Galderma Laboratories, L.P. 2019-11-01
00299-5906-02 1 TUBE in 1 BLISTER PACK (0299-5906-02) / 2 g in 1 TUBE epiduo forte Galderma Laboratories, L.P. 2015-07-01
00299-5906-05 1 TUBE in 1 BLISTER PACK (0299-5906-05) / 5 g in 1 TUBE epiduo forte Galderma Laboratories, L.P. 2015-07-01
00299-5906-15 1 BOTTLE, PUMP in 1 CARTON (0299-5906-15) / 15 g in 1 BOTTL... epiduo forte Galderma Laboratories, L.P. 2015-07-01
00299-5906-30 1 BOTTLE, PUMP in 1 CARTON (0299-5906-30) / 30 g in 1 BOTTL... epiduo forte Galderma Laboratories, L.P. 2015-07-01
00299-5906-45 1 BOTTLE, PUMP in 1 CARTON (0299-5906-45) / 45 g in 1 BOTTL... epiduo forte Galderma Laboratories, L.P. 2015-07-01
00299-5906-60 1 BOTTLE, PUMP in 1 CARTON (0299-5906-60) / 60 g in 1 BOTTL... epiduo forte Galderma Laboratories, L.P. 2015-07-01
00299-5906-70 1 BOTTLE, PUMP in 1 CARTON (0299-5906-70) / 70 g in 1 BOTTL... epiduo forte Galderma Laboratories, L.P. 2015-07-01
00480-3154-45 1 BOTTLE, PUMP in 1 CARTON (0480-3154-45) / 45 g in 1 BOTTL... Adapalene and benzoyl peroxide Teva Pharmaceuticals, Inc. 2022-11-28
45802-0853-45 45 g in 1 BOTTLE, PUMP (45802-853-45) ADAPALENE AND BENZOYL PEROXIDE Padagis Israel Pharmaceuticals Ltd 2022-06-02
46708-0662-45 1 BOTTLE, PUMP in 1 CARTON (46708-662-45) / 45 g in 1 BOTTL... ADAPALENE AND BENZOYL PEROXIDE Alembic Pharmaceuticals Limited 2025-05-21
51672-1384-04 1 BOTTLE, PUMP in 1 CARTON (51672-1384-4) / 60 g in 1 BOTTL... Adapalene and Benzoyl Peroxide Sun Pharmaceutical Industries, Inc. 2021-03-11
51672-1384-09 1 BOTTLE, PUMP in 1 CARTON (51672-1384-9) / 45 g in 1 BOTTL... Adapalene and Benzoyl Peroxide Sun Pharmaceutical Industries, Inc. 2018-10-17
62332-0662-45 1 BOTTLE, PUMP in 1 CARTON (62332-662-45) / 45 g in 1 BOTTL... ADAPALENE AND BENZOYL PEROXIDE Alembic Pharmaceuticals Inc. 2022-08-10
63629-9322-01 45 g in 1 BOTTLE, PUMP (63629-9322-1) ADAPALENE AND BENZOYL PEROXIDE Bryant Ranch Prepack 2022-07-07
68308-0662-45 1 BOTTLE, PUMP in 1 CARTON (68308-662-45) / 45 g in 1 BOTTL... adapalene and benzoyl peroxide Mayne Pharma Inc. 2022-02-01
70771-1716-03 1 BOTTLE, PUMP in 1 BOTTLE, PUMP (70771-1716-3) / 60 g in 1... Adapalene and benzoyl peroxide Zydus Lifesciences Limited 2022-06-06
70771-1716-04 1 BOTTLE, PUMP in 1 BOTTLE, PUMP (70771-1716-4) / 45 g in 1... Adapalene and benzoyl peroxide Zydus Lifesciences Limited 2022-06-06
72162-1432-02 45 g in 1 BOTTLE, PUMP (72162-1432-2) ADAPALENE AND BENZOYL PEROXIDE Bryant Ranch Prepack 2024-03-13
72578-0119-02 1 BOTTLE, PUMP in 1 BOTTLE, PUMP (72578-119-02) / 60 g in 1... Adapalene and benzoyl peroxide Viona Pharmaceuticals Inc 2022-06-06
72578-0119-04 1 BOTTLE, PUMP in 1 BOTTLE, PUMP (72578-119-04) / 45 g in 1... Adapalene and benzoyl peroxide Viona Pharmaceuticals Inc 2022-06-06
Observed labelers: Galderma Laboratories, L.P. (8) · Bryant Ranch Prepack (2) · Sun Pharmaceutical Industries, Inc. (2) · Viona Pharmaceuticals Inc (2) · Zydus Lifesciences Limited (2) · Alembic Pharmaceuticals Inc. (1) · +4 more — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

💲 Pricing (NADAC)

NADAC is CMS's National Average Drug Acquisition Cost — roughly what pharmacies pay to buy the drug. It is an acquisition benchmark, not your copay.
Per gm · median
$0.7063
Range $0.7063–$14.9679 · middle 50% $0.7063–$0.7063 · 7 NDCs
Latest compatible distributions from the CMS NADAC file · dataset watermark 2026-07-10. Prices vary by package and pharmacy; a distribution is shown instead of one misleading number. Rows the dataset is silent on carry no price. No zero-cost conclusion should be drawn.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7
openFDA export observedJul 14, 2026
RxNorm release07/06/2026
Methodology2026-07-full-catalog-v1
  • A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
  • Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
  • Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
  • Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.
This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.