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Acetaminophen 325 MG / dextromethorphan hydrobromide 20 MG / guaifenesin 200 MG / pseudoep... — RxCUI 1673869

RxNorm drug concept · Semantic clinical drug
RxCUI 1673869 Semantic clinical drug · SCD ● Current RxNorm concept 1 FDA product 2 package NDCs Snapshot Jul 14, 2026

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Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI1673869
Official nameAcetaminophen 325 MG / dextromethorphan hydrobromide 20 MG / guaifenesin 200 MG / pseudoephedrine hydrochloride 60 MG Oral Tablet
Concept typeSemantic clinical drug (SCD)
RxNorm statusCurrent RxNorm concept
Also known asAPAP 325 MG / Dextromethorphan Hydrobromide 20 MG / Guaifenesin 200 MG / Pseudoephedrine Hydrochloride 60 MG Oral Tablet; acetaminophen 325 MG / dextromethorphan HBr 20 MG / guaiFENesin 200 MG / pseudoephedrine HCl 60 MG Oral Tablet
FDA products mapped1
Package NDCs mapped2
Reported Medicaid activity (SDUD)298 prescriptions · 1 state & territory Medicaid programs · latest period Q4 2025
RxNorm release07/06/2026
Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Acetaminophen Injection: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist
  • Great question. The IV form is used when you can't take medication by mouth — for example, after surgery, if you're nauseated, or if you need faster, more reliable absorption. It d...
  • Why am I getting acetaminophen through an IV instead of just taking a pill?
  • Yes, Acetaminophen Injection is approved for children — for pain relief in kids 2 years and older, and for fever reduction in patients of all ages, including premature newborns bor...
  • The most important things to watch for are signs of a serious allergic reaction — swelling of your face, mouth, or throat, trouble breathing, or hives — and any new skin rash. Eith...
📖 Read our full Acetaminophen Injection guide →

🕸️ Concept Web — How Acetaminophen 325 MG / dextromethorphan hydrobro... Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.
This page's concept Acetaminophen 325 MG / dextromethorphan hydrobromide 20 MG / guaifenesin 200 MG / pseudoephedrine hydrochloride 60 MG Oral Tablet RxCUI 1673869

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

  1. Ingredients 7

    The active substance itself — no strength, form, or brand attached yet.

    • Acetaminophen 161
    • Dextromethorphan 3289
    • Guaifenesin 5032
    • Pseudoephedrine 8896
    • Acetaminophen / dextromethorphan / guaifenesin / pseudoephedrine 689778
    • Dextromethorphan hydrobromide 102490
    • Pseudoephedrine hydrochloride 91168
  2. Dose forms 9

    The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.

    • Acetaminophen / dextromethorphan / guaifenesin / pseudoephedrine Oral Tablet 376336
    • Acetaminophen / dextromethorphan hydrobromide / guaifenesin / pseudoephedrine hydrochloride Oral Tablet 2648561
    • Acetaminophen / dextromethorphan / guaifenesin / pseudoephedrine Oral Product 1155910
    • Acetaminophen / dextromethorphan / guaifenesin / pseudoephedrine Pill 1155911
    • Acetaminophen / dextromethorphan hydrobromide / guaifenesin / pseudoephedrine hydrochloride Oral Product 2661518
    • Acetaminophen / dextromethorphan hydrobromide / guaifenesin / pseudoephedrine hydrochloride Pill 2661732
    • Oral Tablet 317541
    • Oral Product 1151131
    • +1 more in this family
  3. Clinical & branded drugs 4

    Ingredient + strength + dose form. These are the concepts real FDA products actually carry.

    • Acetaminophen 325 MG 315263
    • Dextromethorphan hydrobromide 20 MG 1037200
    • Guaifenesin 200 MG 317384
    • Pseudoephedrine hydrochloride 60 MG 996721

Showing up to 8 concepts per family — 19 of 20 stored related concepts drawn.
These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

  • Acetaminophen 325 MG SCDC · 315263
  • Dextromethorphan hydrobromide 20 MG SCDC · 1037200
  • Guaifenesin 200 MG SCDC · 317384
  • Pseudoephedrine hydrochloride 60 MG SCDC · 996721
  • Acetaminophen / dextromethorphan / guaifenesin / pseudoephedrine Oral Tablet SCDF · 376336
  • Acetaminophen / dextromethorphan hydrobromide / guaifenesin / pseudoephedrine hydrochloride Oral Tablet SCDFP · 2648561
  • Acetaminophen / dextromethorphan / guaifenesin / pseudoephedrine Oral Product SCDG · 1155910
  • Acetaminophen / dextromethorphan / guaifenesin / pseudoephedrine Pill SCDG · 1155911
  • Acetaminophen / dextromethorphan hydrobromide / guaifenesin / pseudoephedrine hydrochloride Oral Product SCDGP · 2661518
  • Acetaminophen / dextromethorphan hydrobromide / guaifenesin / pseudoephedrine hydrochloride Pill SCDGP · 2661732

📦 FDA Products & Package NDCs

1 product · 2 package NDCs
2 package NDCs map to RxCUI 1673869 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.
Package NDC Package Brand / generic name Labeler Marketing start
50991-0535-01 100 TABLET in 1 BOTTLE (50991-535-01) Duraflu Poly Pharmaceuticals, Inc. 2015-10-01
50991-0535-02 6 BLISTER PACK in 1 CARTON (50991-535-02) / 2 TABLET in 1 B... Duraflu Poly Pharmaceuticals, Inc. 2015-10-01
Observed labelers: Poly Pharmaceuticals, Inc. (2) — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

💲 Pricing (NADAC)

NADAC is CMS's National Average Drug Acquisition Cost — roughly what pharmacies pay to buy the drug. It is an acquisition benchmark, not your copay.
Per ea · median
$0.9041
Range $0.9041–$0.9041 · middle 50% $0.9041–$0.9041 · 1 NDCs
Latest compatible distributions from the CMS NADAC file · dataset watermark 2026-07-10. Prices vary by package and pharmacy; a distribution is shown instead of one misleading number. Rows the dataset is silent on carry no price. No zero-cost conclusion should be drawn.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7
openFDA export observedJul 14, 2026
RxNorm release07/06/2026
Methodology2026-07-full-catalog-v1
  • A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
  • Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
  • Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
  • Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.
This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.