Home › NDC Lookup › RxCUI directory › RxCUI 1867612

10 ML bupivacaine hydrochloride 2.5 MG/ML / epinephrine 0.005 MG/ML Injection [Marcaine wi... — RxCUI 1867612

RxNorm drug concept · Semantic branded drug
RxCUI 1867612 Semantic branded drug · SBD ● Current RxNorm concept 18 FDA products 21 package NDCs Snapshot Jul 14, 2026

This page is curated, coded, and maintained by

Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI1867612
Official name10 ML bupivacaine hydrochloride 2.5 MG/ML / epinephrine 0.005 MG/ML Injection [Marcaine with Epinephrine]
Concept typeSemantic branded drug (SBD)
RxNorm statusCurrent RxNorm concept
Also known asMarcaine 0.25 % / EPINEPHrine 1:200,000 per 10 ML Injection; Marcaine 0.25 % / EPINEPHrine 1:200,000 in 10 ML Injection
FDA products mapped18
Package NDCs mapped21
Reported Medicaid activity (SDUD)6,725 prescriptions · 25 state & territory Medicaid programs · latest period Q4 2025
RxNorm release07/06/2026
Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Epinephrine Injection: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist
  • Use it at the first signs of a serious allergic reaction — things like throat tightening, trouble breathing, a drop in blood pressure, severe hives, or vomiting after exposure to a...
  • When exactly should I use my epinephrine injection?
  • Yes, it really matters. Always inject into the outer thigh — you can even go through your clothing in a hurry. Never use the buttock (that raises the risk of a serious infection ca...
  • Where exactly do I inject it, and does it matter?
📖 Read our full Epinephrine Injection guide →

🕸️ Concept Web — How 10 ML bupivacaine hydrochloride 2.5 MG/ML / epin... Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.
This page's concept 10 ML bupivacaine hydrochloride 2.5 MG/ML / epinephrine 0.005 MG/ML Injection [Marcaine with Epinephrine] RxCUI 1867612

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

  1. Ingredients 4

    The active substance itself — no strength, form, or brand attached yet.

    • Bupivacaine 1815
    • Epinephrine 3992
    • Bupivacaine / epinephrine 107606
    • Bupivacaine hydrochloride 267396
  2. Brand names 1

    The same medicine's trade names. A brand name alone says nothing about strength or form.

    • Marcaine with Epinephrine 1372694
  3. Dose forms 9

    The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.

    • Bupivacaine / epinephrine Injection 1672916
    • Bupivacaine hydrochloride / epinephrine Injection 2645891
    • Bupivacaine / epinephrine Injectable Product 1151351
    • Bupivacaine hydrochloride / epinephrine Injectable Product 2662588
    • Bupivacaine / epinephrine Injection [Marcaine with Epinephrine] 1673146
    • Bupivacaine hydrochloride / epinephrine Injection [Marcaine with Epinephrine] 2658029
    • Marcaine with Epinephrine Injectable Product 1180419
    • Injection 1649574
    • +1 more in this family
  4. Clinical & branded drugs 4

    Ingredient + strength + dose form. These are the concepts real FDA products actually carry.

Showing up to 8 concepts per family — 17 of 18 stored related concepts drawn.
These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

  • 10 ML bupivacaine hydrochloride 2.5 MG/ML / epinephrine 0.005 MG/ML Injection SCD · 1867594
  • Bupivacaine hydrochloride 2.5 MG/ML SCDC · 1012376
  • Epinephrine 0.005 MG/ML SCDC · 330427
  • Bupivacaine / epinephrine Injection SCDF · 1672916
  • Bupivacaine hydrochloride / epinephrine Injection SCDFP · 2645891
  • Bupivacaine / epinephrine Injectable Product SCDG · 1151351
  • Bupivacaine hydrochloride / epinephrine Injectable Product SCDGP · 2662588

Brand-Name Concepts

  • Bupivacaine hydrochloride 2.5 MG/ML / epinephrine 0.005 MG/ML [Marcaine with Epinephrine] SBDC · 1012379
  • Bupivacaine / epinephrine Injection [Marcaine with Epinephrine] SBDF · 1673146
  • Bupivacaine hydrochloride / epinephrine Injection [Marcaine with Epinephrine] SBDFP · 2658029
  • Marcaine with Epinephrine Injectable Product SBDG · 1180419
  • Marcaine with Epinephrine BN · 1372694

📦 FDA Products & Package NDCs

18 products · 21 package NDCs
21 package NDCs map to RxCUI 1867612 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.
Package NDC Package Brand / generic name Labeler Marketing start
00409-0525-25 25 VIAL, MULTI-DOSE in 1 TRAY (0409-0525-25) / 50 mL in 1 V... Marcaine Hospira, Inc. 2024-12-09
00409-1530-25 25 VIAL, SINGLE-DOSE in 1 TRAY (0409-1530-25) / 30 mL in 1... Marcaine Hospira, Inc. 2025-08-25
00409-1541-10 10 VIAL, SINGLE-DOSE in 1 CARTON (0409-1541-10) / 30 mL in... Marcaine with Epinephrine Hospira, Inc. 2022-09-06
00409-1582-10 10 VIAL, SINGLE-DOSE in 1 TRAY (0409-1582-10) / 10 mL in 1... Marcaine Hospira, Inc. 2005-07-27
00409-1582-29 10 VIAL, SINGLE-DOSE in 1 CARTON (0409-1582-29) / 30 mL in... Marcaine Hospira, Inc. 2005-08-08
00409-1587-50 1 VIAL, MULTI-DOSE in 1 CARTON (0409-1587-50) / 50 mL in 1... Marcaine Hospira, Inc. 2006-01-17
00409-1746-10 10 VIAL, SINGLE-DOSE in 1 CARTON (0409-1746-10) / 10 mL in... Marcaine with Epinephrine Hospira, Inc. 2005-12-09
00409-1746-30 10 VIAL, SINGLE-DOSE in 1 CARTON (0409-1746-30) / 30 mL in... Marcaine with Epinephrine Hospira, Inc. 2005-09-12
00409-1749-10 10 VIAL, SINGLE-DOSE in 1 CARTON (0409-1749-10) / 10 mL in... Marcaine with Epinephrine Hospira, Inc. 2005-09-22
00409-1749-29 10 VIAL, SINGLE-DOSE in 1 CARTON (0409-1749-29) / 30 mL in... Marcaine with Epinephrine Hospira, Inc. 2005-09-12
00409-1752-50 1 VIAL, MULTI-DOSE in 1 CARTON (0409-1752-50) / 50 mL in 1... Marcaine with Epinephrine Hospira, Inc. 2006-02-06
00409-1755-50 1 VIAL, MULTI-DOSE in 1 CARTON (0409-1755-50) / 50 mL in 1... Marcaine with Epinephrine Hospira, Inc. 2006-03-22
00409-2253-25 25 VIAL, SINGLE-DOSE in 1 TRAY (0409-2253-25) / 30 mL in 1... Marcaine Hospira, Inc. 2025-04-14
00409-2510-25 25 VIAL, SINGLE-DOSE in 1 TRAY (0409-2510-25) / 10 mL in 1... Marcaine Hospira, Inc. 2025-08-28
00409-3812-01 1 VIAL, MULTI-DOSE in 1 CARTON (0409-3812-01) / 50 mL in 1... Marcaine with Epinephrine Hospira, Inc. 2022-09-06
00409-4208-10 10 VIAL, SINGLE-DOSE in 1 CARTON (0409-4208-10) / 30 mL in... Marcaine with Epinephrine Hospira, Inc. 2022-09-26
00409-5010-25 25 VIAL, SINGLE-DOSE in 1 TRAY (0409-5010-25) / 10 mL in 1... Marcaine Hospira, Inc. 2025-02-03
00409-5738-10 10 VIAL, SINGLE-DOSE in 1 CARTON (0409-5738-10) / 10 mL in... Marcaine with Epinephrine Hospira, Inc. 2022-09-06
00409-6581-01 1 VIAL, MULTI-DOSE in 1 CARTON (0409-6581-01) / 50 mL in 1... Marcaine with Epinephrine Hospira, Inc. 2022-09-26
00409-7535-25 25 VIAL, SINGLE-DOSE in 1 TRAY (0409-7535-25) / 30 mL in 1... Marcaine Hospira, Inc. 2025-05-27
00409-8126-10 10 VIAL, SINGLE-DOSE in 1 CARTON (0409-8126-10) / 10 mL in... Marcaine with Epinephrine Hospira, Inc. 2022-09-06
Observed labelers: Hospira, Inc. (21) — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🧾 Billing Codes (HCPCS)

Medical billing codes (HCPCS "J-codes") that connect to this concept's packages — used mostly when a clinic or hospital bills for a drug it administers. Each code links to its full billing page.
CodeDescriptorMapped packagesSources
J0665 Inj, bupivacaine, nos, 0.5mg 9 CMS
⚠ A crosswalk is not coverage: an NDC↔HCPCS mapping does not guarantee any payer covers or pays the code. Always verify the current payer policy before billing.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7
openFDA export observedJul 14, 2026
RxNorm release07/06/2026
Methodology2026-07-full-catalog-v1
  • A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
  • Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
  • Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
  • Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.
This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.