Hydrochlorothiazide 12.5 MG / lisinopril 20 MG Oral Tablet — RxCUI 197886
RxNorm drug concept · Semantic clinical drug
RxCUI 197886
Semantic clinical drug · SCD
● Current RxNorm concept 59 FDA products
167 package NDCs
Snapshot Jul 14, 2026
What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.
🗂️ Key Facts
RxCUI197886
Official nameHydrochlorothiazide 12.5 MG / lisinopril 20 MG Oral Tablet
Concept typeSemantic clinical drug (SCD)
RxNorm statusCurrent RxNorm concept
Also known asHCTZ 12.5 MG / lisinopril 20 MG Oral Tablet
FDA products mapped59
Package NDCs mapped167
Reported Medicaid activity (SDUD)999,534 prescriptions · 52 state & territory Medicaid programs · latest period Q4 2025
RxNorm release07/06/2026
Snapshot dataJul 14, 2026
📖 Skip the Codes — Read It in Plain English.
Our pharmacist-built guide to Lisinopril and Hydrochlorothiazide: what it is, how it’s used, side effects, and interactions.
📗 Our plain-language guide HelloPharmacist
- Great question. Lisinopril relaxes your blood vessels by blocking a chemical that causes them to tighten. Hydrochlorothiazide helps your kidneys remove extra salt and fluid. Togeth...
- What exactly is this medication doing for me — why do I need two drugs in one pill?
- Yes, that cough is a known side effect of the lisinopril part of this combination. It's not dangerous, but it can be really annoying. Don't just stop the medication on your own — t...
- I've noticed a dry, nagging cough since I started this. Is that from the medication?
🕸️ Concept Web — How Hydrochlorothiazide 12.5 MG / lisinopril 20 MG O... Connects
One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.
This page's concept
Hydrochlorothiazide 12.5 MG / lisinopril 20 MG Oral Tablet
RxCUI 197886 Semantic clinical drug · SCD
Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.
-
Ingredients 3
The active substance itself — no strength, form, or brand attached yet.
-
Hydrochlorothiazide
5487IN -
Lisinopril
29046IN -
Hydrochlorothiazide / lisinopril
214618MIN
-
Hydrochlorothiazide
-
Brand names 1
The same medicine's trade names. A brand name alone says nothing about strength or form.
-
Zestoretic
85783BN
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Zestoretic
-
Dose forms 9
The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.
-
Hydrochlorothiazide / lisinopril Oral Tablet
372613SCDF -
Hydrochlorothiazide / lisinopril Oral Product
1162124SCDG -
Hydrochlorothiazide / lisinopril Pill
1162125SCDG -
Hydrochlorothiazide / lisinopril Oral Tablet [Zestoretic]
823970SBDF -
Zestoretic Oral Product
1187277SBDG -
Zestoretic Pill
1187278SBDG -
Oral Tablet
317541DF -
Oral Product
1151131DFG - +1 more in this family
-
Hydrochlorothiazide / lisinopril Oral Tablet
-
Clinical & branded drugs 4
Ingredient + strength + dose form. These are the concepts real FDA products actually carry.
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Hydrochlorothiazide 12.5 MG
316047SCDC -
Lisinopril 20 MG
316153SCDC -
Hydrochlorothiazide 12.5 MG / lisinopril 20 MG Oral Tablet [Zestoretic]
823982SBD -
Hydrochlorothiazide 12.5 MG / lisinopril 20 MG [Zestoretic]
823980SBDC
-
Hydrochlorothiazide 12.5 MG
Showing up to 8 concepts per family — 16 of 17 stored related concepts drawn.
These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.
🔀 Generic ⇄ Brand Crosswalk
The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.
Generic (Clinical) Concepts
-
Hydrochlorothiazide 12.5 MG
SCDC · 316047 -
Lisinopril 20 MG
SCDC · 316153 -
Hydrochlorothiazide / lisinopril Oral Tablet
SCDF · 372613 -
Hydrochlorothiazide / lisinopril Oral Product
SCDG · 1162124 -
Hydrochlorothiazide / lisinopril Pill
SCDG · 1162125
Brand-Name Concepts
-
Hydrochlorothiazide 12.5 MG / lisinopril 20 MG Oral Tablet [Zestoretic]
SBD · 823982 -
Hydrochlorothiazide 12.5 MG / lisinopril 20 MG [Zestoretic]
SBDC · 823980 -
Hydrochlorothiazide / lisinopril Oral Tablet [Zestoretic]
SBDF · 823970 -
Zestoretic Oral Product
SBDG · 1187277 -
Zestoretic Pill
SBDG · 1187278 -
Zestoretic
BN · 85783
📦 FDA Products & Package NDCs
59 products · 167 package NDCs
167 package NDCs map to RxCUI 197886 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.
| Package NDC | Package | Brand / generic name | Labeler | Marketing start |
|---|---|---|---|---|
| 00591-0860-01 | 100 TABLET in 1 BOTTLE, PLASTIC (0591-0860-01) | Lisinopril and Hydrochlorothiazide | Actavis Pharma, Inc. | 2002-07-01 |
| 00591-0860-05 | 500 TABLET in 1 BOTTLE, PLASTIC (0591-0860-05) | Lisinopril and Hydrochlorothiazide | Actavis Pharma, Inc. | 2002-07-01 |
| 00591-0861-01 | 100 TABLET in 1 BOTTLE, PLASTIC (0591-0861-01) | Lisinopril and Hydrochlorothiazide | Actavis Pharma, Inc. | 2003-03-04 |
| 00591-0861-05 | 500 TABLET in 1 BOTTLE, PLASTIC (0591-0861-05) | Lisinopril and Hydrochlorothiazide | Actavis Pharma, Inc. | 2003-03-04 |
| 00591-0862-01 | 100 TABLET in 1 BOTTLE, PLASTIC (0591-0862-01) | Lisinopril and Hydrochlorothiazide | Actavis Pharma, Inc. | 2003-03-04 |
| 00591-0862-05 | 500 TABLET in 1 BOTTLE, PLASTIC (0591-0862-05) | Lisinopril and Hydrochlorothiazide | Actavis Pharma, Inc. | 2003-03-04 |
| 43063-0458-30 | 30 TABLET in 1 BOTTLE, PLASTIC (43063-458-30) | Lisinopril and Hydrochlorothiazide | PD-Rx Pharmaceuticals, Inc. | 2015-12-10 |
| 43063-0458-90 | 90 TABLET in 1 BOTTLE, PLASTIC (43063-458-90) | Lisinopril and Hydrochlorothiazide | PD-Rx Pharmaceuticals, Inc. | 2015-12-10 |
| 43547-0420-10 | 100 TABLET in 1 BOTTLE (43547-420-10) | Lisinopril and Hydrochlorothiazide | Solco Healthcare LLC | 2015-03-12 |
| 43547-0420-11 | 1000 TABLET in 1 BOTTLE (43547-420-11) | Lisinopril and Hydrochlorothiazide | Solco Healthcare LLC | 2015-03-12 |
| 43547-0420-50 | 500 TABLET in 1 BOTTLE (43547-420-50) | Lisinopril and Hydrochlorothiazide | Solco Healthcare LLC | 2015-03-12 |
| 43547-0421-10 | 100 TABLET in 1 BOTTLE (43547-421-10) | Lisinopril and Hydrochlorothiazide | Solco Healthcare LLC | 2015-03-12 |
| 43547-0421-11 | 1000 TABLET in 1 BOTTLE (43547-421-11) | Lisinopril and Hydrochlorothiazide | Solco Healthcare LLC | 2015-03-12 |
| 43547-0421-50 | 500 TABLET in 1 BOTTLE (43547-421-50) | Lisinopril and Hydrochlorothiazide | Solco Healthcare LLC | 2015-03-12 |
| 43547-0422-10 | 100 TABLET in 1 BOTTLE (43547-422-10) | Lisinopril and Hydrochlorothiazide | Solco Healthcare LLC | 2015-03-12 |
| 43547-0422-11 | 1000 TABLET in 1 BOTTLE (43547-422-11) | Lisinopril and Hydrochlorothiazide | Solco Healthcare LLC | 2015-03-12 |
| 43547-0422-50 | 500 TABLET in 1 BOTTLE (43547-422-50) | Lisinopril and Hydrochlorothiazide | Solco Healthcare LLC | 2015-03-12 |
| 50090-2565-00 | 30 TABLET in 1 BOTTLE (50090-2565-0) | Lisinopril and Hydrochlorothiazide | A-S Medication Solutions | 2016-10-27 |
| 50090-2565-01 | 90 TABLET in 1 BOTTLE (50090-2565-1) | Lisinopril and Hydrochlorothiazide | A-S Medication Solutions | 2016-10-28 |
| 50090-2565-02 | 100 TABLET in 1 BOTTLE (50090-2565-2) | Lisinopril and Hydrochlorothiazide | A-S Medication Solutions | 2023-03-27 |
| 50090-2974-00 | 30 TABLET in 1 BOTTLE (50090-2974-0) | Lisinopril and Hydrochlorothiazide | A-S Medication Solutions | 2017-05-18 |
| 50090-2974-01 | 100 TABLET in 1 BOTTLE (50090-2974-1) | Lisinopril and Hydrochlorothiazide | A-S Medication Solutions | 2017-05-01 |
| 50090-2974-02 | 90 TABLET in 1 BOTTLE (50090-2974-2) | Lisinopril and Hydrochlorothiazide | A-S Medication Solutions | 2018-08-03 |
| 50090-6204-00 | 30 TABLET in 1 BOTTLE (50090-6204-0) | Lisinopril and Hydrochlorothiazide | A-S Medication Solutions | 2022-11-04 |
| 50090-6204-01 | 90 TABLET in 1 BOTTLE (50090-6204-1) | Lisinopril and Hydrochlorothiazide | A-S Medication Solutions | 2022-11-04 |
| 50090-6204-02 | 100 TABLET in 1 BOTTLE (50090-6204-2) | Lisinopril and Hydrochlorothiazide | A-S Medication Solutions | 2023-03-09 |
| 50090-6752-00 | 90 TABLET in 1 BOTTLE (50090-6752-0) | Lisinopril and Hydrochlorothiazide | A-S Medication Solutions | 2023-10-17 |
| 51407-0564-05 | 500 TABLET in 1 BOTTLE (51407-564-05) | LISINOPRIL and HYDROCHLOROTHIAZIDE | GSMS, Incorporated | 2025-02-15 |
| 51407-0564-90 | 90 TABLET in 1 BOTTLE (51407-564-90) | LISINOPRIL and HYDROCHLOROTHIAZIDE | GSMS, Incorporated | 2025-02-15 |
| 51407-0565-05 | 500 TABLET in 1 BOTTLE (51407-565-05) | LISINOPRIL and HYDROCHLOROTHIAZIDE | GSMS, Incorporated | 2025-02-15 |
| 51407-0565-90 | 90 TABLET in 1 BOTTLE (51407-565-90) | LISINOPRIL and HYDROCHLOROTHIAZIDE | GSMS, Incorporated | 2025-02-15 |
| 51407-0566-05 | 500 TABLET in 1 BOTTLE (51407-566-05) | LISINOPRIL and HYDROCHLOROTHIAZIDE | GSMS, Incorporated | 2025-02-15 |
| 51407-0566-90 | 90 TABLET in 1 BOTTLE (51407-566-90) | LISINOPRIL and HYDROCHLOROTHIAZIDE | GSMS, Incorporated | 2025-02-15 |
| 51655-0311-26 | 90 TABLET in 1 BOTTLE, PLASTIC (51655-311-26) | Lisinopril and Hydrochlorothiazide | Northwind Health Company, LLC | 2022-09-14 |
| 51655-0311-52 | 30 TABLET in 1 BOTTLE, PLASTIC (51655-311-52) | Lisinopril and Hydrochlorothiazide | Northwind Health Company, LLC | 2022-07-14 |
| 51655-0414-26 | 90 TABLET in 1 BOTTLE, PLASTIC (51655-414-26) | Lisinopril and Hydrochlorothiazide | Northwind Health Company, LLC | 2021-06-29 |
| 51655-0414-30 | 30 TABLET in 1 BOTTLE, DISPENSING (51655-414-30) | Lisinopril and Hydrochlorothiazide | Northwind Health Company, LLC | 2014-08-25 |
| 52427-0435-90 | 90 TABLET in 1 BOTTLE (52427-435-90) | Zestoretic | Almatica Pharma Inc. | 2015-04-15 |
| 52427-0436-90 | 90 TABLET in 1 BOTTLE (52427-436-90) | Zestoretic | Almatica Pharma Inc. | 2015-04-15 |
| 52427-0437-90 | 90 TABLET in 1 BOTTLE (52427-437-90) | Zestoretic | Almatica Pharma Inc. | 2015-04-15 |
| 60760-0519-90 | 90 TABLET in 1 BOTTLE, PLASTIC (60760-519-90) | Lisinopril and Hydrochlorothiazide | St. Mary's Medical Park Pharmacy | 2022-05-10 |
| 63187-0050-00 | 100 TABLET in 1 BOTTLE, PLASTIC (63187-050-00) | Lisinopril and hydrochlorothiazide | Proficient Rx LP | 2020-07-14 |
| 63187-0050-30 | 30 TABLET in 1 BOTTLE, PLASTIC (63187-050-30) | Lisinopril and hydrochlorothiazide | Proficient Rx LP | 2018-11-01 |
| 63187-0050-60 | 60 TABLET in 1 BOTTLE, PLASTIC (63187-050-60) | Lisinopril and hydrochlorothiazide | Proficient Rx LP | 2020-07-14 |
| 63187-0050-90 | 90 TABLET in 1 BOTTLE, PLASTIC (63187-050-90) | Lisinopril and hydrochlorothiazide | Proficient Rx LP | 2020-07-14 |
| 63187-0051-00 | 100 TABLET in 1 BOTTLE, PLASTIC (63187-051-00) | Lisinopril and hydrochlorothiazide | Proficient Rx LP | 2020-07-14 |
| 63187-0051-30 | 30 TABLET in 1 BOTTLE, PLASTIC (63187-051-30) | Lisinopril and hydrochlorothiazide | Proficient Rx LP | 2018-11-01 |
| 63187-0051-60 | 60 TABLET in 1 BOTTLE, PLASTIC (63187-051-60) | Lisinopril and hydrochlorothiazide | Proficient Rx LP | 2020-07-14 |
| 63187-0051-90 | 90 TABLET in 1 BOTTLE, PLASTIC (63187-051-90) | Lisinopril and hydrochlorothiazide | Proficient Rx LP | 2020-07-14 |
| 63629-4470-01 | 30 TABLET in 1 BOTTLE (63629-4470-1) | Lisinopril and Hydrochlorothiazide | Bryant Ranch Prepack | 2011-03-24 |
Observed labelers:
Bryant Ranch Prepack (18) ·
Aurobindo Pharma Limited (15) ·
Proficient Rx LP (15) ·
Aphena Pharma Solutions - Tennessee, LLC (13) ·
Cipla USA Inc. (12) ·
Exelan Pharmaceuticals, Inc. (12)
· +17 more — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.
🗃️ Sources & Limits
Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7
openFDA export observedJul 14, 2026
RxNorm release07/06/2026
Methodology2026-07-full-catalog-v1
- A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
- Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
- Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
- Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.
This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.
Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.