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Hydrocortisone 10 MG/ML / neomycin 3.5 MG/ML / polymyxin B 10000 UNT/ML Otic Solution — RxCUI 204423

Name: Hydrocortisone 10 MG/ML / neomycin 3.5 MG/ML / polymyxin B 10000 UNT/ML Otic Solution (RxCUI 204423)
Creator: Brian Staiger, PharmD

RxNorm drug concept · Semantic clinical drug

RxCUI 204423 Semantic clinical drug · SCD ● Current RxNorm concept 9 FDA products 9 package NDCs Snapshot Jul 14, 2026

This page is curated, coded, and maintained by Dr. Brian Staiger, PharmD

Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI204423

Official nameHydrocortisone 10 MG/ML / neomycin 3.5 MG/ML / polymyxin B 10000 UNT/ML Otic Solution

Concept typeSemantic clinical drug (SCD)

RxNorm statusCurrent RxNorm concept

Also known ashydrocortisone 10 MG / neomycin 3.5 MG / polymyxin B 10,000 UNT per ML Otic Solution; neomycin sulfate 0.35 % / polymyxin B sulfate 10,000 UNT/ML / hydrocortisone 1 % Otic Solution; hydrocortisone 1 % / neomycin (as neomycin sulfate) 0.35 % / polymyxin B (as polymyxin B sulfate) 10,000 UNT/ML Otic Solution

FDA products mapped9

Package NDCs mapped9

Reported Medicaid activity (SDUD)165,158 prescriptions · 52 state & territory Medicaid programs · latest period Q4 2025

RxNorm release07/06/2026

Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Hydrocortisone Rectal: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist

It is used as add-on treatment for ulcerative colitis, especially when it affects the lower or left side of the colon. It is meant to be used along with other supportive measures y...
It's usually used once at night. Lie on your left side while you use it and for about 30 minutes after. Try to hold it in at least an hour, ideally all night. Your doctor may sugge...
How do I use it, and how long do I keep it in?
A usual course is about 21 days, or until you're in remission. Many people feel better within 3 to 5 days. If you use it longer, your doctor will taper you off to every other night...

📖 Read our full Hydrocortisone Rectal guide →

🕸️ Concept Web — How Hydrocortisone 10 MG/ML / neomycin 3.5 MG/ML / p... Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.

This page's concept Hydrocortisone 10 MG/ML / neomycin 3.5 MG/ML / polymyxin B 10000 UNT/ML Otic Solution RxCUI 204423 Semantic clinical drug · SCD

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

Ingredients 4

The active substance itself — no strength, form, or brand attached yet.
- Hydrocortisone 5492 IN
- Neomycin 7299 IN
- Polymyxin B 8536 IN
- Hydrocortisone / neomycin / polymyxin B 217627 MIN
Brand names 1

The same medicine's trade names. A brand name alone says nothing about strength or form.
- Cortisporin 21659 BN
Dose forms 6

The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.
- Hydrocortisone / neomycin / polymyxin B Otic Solution 378643 SCDF
- Hydrocortisone / neomycin / polymyxin B Otic Product 1163423 SCDG
- Hydrocortisone / neomycin / polymyxin B Otic Solution [Cortisporin] 365354 SBDF
- Cortisporin Otic Product 1170982 SBDG
- Otic Solution 316973 DF
- Otic Product 1151134 DFG
Clinical & branded drugs 5

Ingredient + strength + dose form. These are the concepts real FDA products actually carry.
- Hydrocortisone 10 MG/ML 316057 SCDC
- Neomycin 3.5 MG/ML 316332 SCDC
- Polymyxin B 10000 UNT/ML 316526 SCDC
- Hydrocortisone 10 MG/ML / neomycin 3.5 MG/ML / polymyxin B 10000 UNT/ML Otic Solution [Cortisporin] 206511 SBD
- Hydrocortisone 10 MG/ML / neomycin 3.5 MG/ML / polymyxin B 10000 UNT/ML [Cortisporin] 825188 SBDC

Showing up to 8 concepts per family — 16 of 16 stored related concepts drawn.

These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

Hydrocortisone 10 MG/ML SCDC · 316057
Neomycin 3.5 MG/ML SCDC · 316332
Polymyxin B 10000 UNT/ML SCDC · 316526
Hydrocortisone / neomycin / polymyxin B Otic Solution SCDF · 378643
Hydrocortisone / neomycin / polymyxin B Otic Product SCDG · 1163423

Brand-Name Concepts

Hydrocortisone 10 MG/ML / neomycin 3.5 MG/ML / polymyxin B 10000 UNT/ML Otic Solution [Cortisporin] SBD · 206511
Hydrocortisone 10 MG/ML / neomycin 3.5 MG/ML / polymyxin B 10000 UNT/ML [Cortisporin] SBDC · 825188
Hydrocortisone / neomycin / polymyxin B Otic Solution [Cortisporin] SBDF · 365354
Cortisporin Otic Product SBDG · 1170982
Cortisporin BN · 21659

📦 FDA Products & Package NDCs

9 products · 9 package NDCs

9 package NDCs map to RxCUI 204423 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.

Package NDC	Package	Brand / generic name	Labeler	Marketing start
24208-0631-10	1 BOTTLE, DROPPER in 1 CARTON (24208-631-10) / 10 mL in 1 B...	Neomycin and Polymyxin B Sulfates and Hydrocortisone	Bausch & Lomb Incoporated	1995-12-29
50090-0433-00	1 BOTTLE, DROPPER in 1 CARTON (50090-0433-0) / 10 mL in 1 B...	Neomycin and Polymyxin B Sulfates and Hydrocortisone	A-S Medication Solutions	2016-06-29
60219-2083-01	1 BOTTLE in 1 CARTON (60219-2083-1) / 10 mL in 1 BOTTLE	NEOMYCIN AND POLYMYXIN B SULFATES AND HYDROCORTISONE	Amneal Pharmaceuticals NY LLC	2025-10-29
61314-0646-10	1 BOTTLE in 1 CARTON (61314-646-10) / 10 mL in 1 BOTTLE	Neomycin and Polymyxin B Sulfates and Hydrocortisone	Sandoz Inc	2003-03-18
63187-0270-10	1 BOTTLE, DROPPER in 1 CARTON (63187-270-10) / 10 mL in 1 B...	Neomycin and Polymyxin B Sulfates and Hydrocortisone	Proficient Rx LP	2015-02-02
63187-0568-10	10 mL in 1 BOTTLE (63187-568-10)	Neomycin and Polymyxin B Sulfates and Hydrocortisone	Proficient Rx LP	2018-12-01
68071-4174-01	10 mL in 1 BOX (68071-4174-1)	Neomycin and Polymyxin B Sulfates and Hydrocortisone	NuCare Pharmaceuticals,Inc.	2017-12-05
70518-0763-00	1 BOTTLE, DROPPER in 1 CARTON (70518-0763-0) / 10 mL in 1 B...	Neomycin and Polymyxin B Sulfates and Hydrocortisone	REMEDYREPACK INC.	2017-10-06
76420-0104-10	10 mL in 1 BOTTLE, DROPPER (76420-104-10)	Neomycin and Polymyxin B Sulfates and Hydrocortisone	Asclemed USA, Inc.	2020-10-30

Observed labelers: Proficient Rx LP (2) · A-S Medication Solutions (1) · Amneal Pharmaceuticals NY LLC (1) · Asclemed USA, Inc. (1) · Bausch & Lomb Incoporated (1) · NuCare Pharmaceuticals,Inc. (1) · +2 more — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7

openFDA export observedJul 14, 2026

RxNorm release07/06/2026

Methodology2026-07-full-catalog-v1

A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.

This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.