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Acetaminophen 33.3 MG/ML / chlorpheniramine maleate 0.133 MG/ML / dextromethorphan hydrobr... — RxCUI 2049283

Name: Acetaminophen 33.3 MG/ML / chlorpheniramine maleate 0.133 MG/ML / dextromethorphan hy… (RxCUI 2049283)
Creator: Brian Staiger, PharmD

RxNorm drug concept · Semantic clinical drug

RxCUI 2049283 Semantic clinical drug · SCD ● Current RxNorm concept 1 FDA product 1 package NDC Snapshot Jul 14, 2026

This page is curated, coded, and maintained by Dr. Brian Staiger, PharmD

Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI2049283

Official nameAcetaminophen 33.3 MG/ML / chlorpheniramine maleate 0.133 MG/ML / dextromethorphan hydrobromide 1 MG/ML / pseudoephedrine hydrochloride 2 MG/ML Oral Solution

Concept typeSemantic clinical drug (SCD)

RxNorm statusCurrent RxNorm concept

Also known asacetaminophen 1000 MG / chlorpheniramine maleate 4 MG / dextromethorphan HBr 30 MG / pseudoephedrine HCl 60 MG per 30 ML Oral Solution; acetaminophen 1000 MG / chlorpheniramine maleate 4 MG / dextromethorphan HBr 30 MG / pseudoephedrine HCl 60 MG in 30 mL Oral Solution; APAP 33.3 MG/ML / Chlorpheniramine Maleate 0.133 MG/ML / Dextromethorphan Hydrobromide 1 MG/ML / Pseudoephedrine Hydrochloride 2 MG/ML Oral Solution

FDA products mapped1

Package NDCs mapped1

RxNorm release07/06/2026

Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Acetaminophen Injection: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist

It treats mild to moderate pain, and moderate to severe pain when used with opioid medicines. It also lowers fever. It is given through a vein in a healthcare setting.
What is Acetaminophen Injection used for?
It is given as an IV infusion over 15 minutes by a healthcare professional. Your dose depends on your age and weight. Your care team follows the label and your prescriber's orders.
The most common are nausea and vomiting. Adults may also get headache or trouble sleeping. Children may have constipation or itching.

📖 Read our full Acetaminophen Injection guide →

🕸️ Concept Web — How Acetaminophen 33.3 MG/ML / chlorpheniramine male... Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.

This page's concept Acetaminophen 33.3 MG/ML / chlorpheniramine maleate 0.133 MG/ML / dextromethorphan hydrobromide 1 MG/ML / pseudoephedrine hydrochloride 2 MG/ML Oral Solution RxCUI 2049283 Semantic clinical drug · SCD

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

Ingredients 8

The active substance itself — no strength, form, or brand attached yet.
- Acetaminophen 161 IN
- Chlorpheniramine 2400 IN
- Dextromethorphan 3289 IN
- Pseudoephedrine 8896 IN
- Acetaminophen / chlorpheniramine / dextromethorphan / pseudoephedrine 689582 MIN
- Chlorpheniramine maleate 142429 PIN
- Dextromethorphan hydrobromide 102490 PIN
- Pseudoephedrine hydrochloride 91168 PIN
Dose forms 9

The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.
- Acetaminophen / chlorpheniramine / dextromethorphan / pseudoephedrine Oral Solution 374770 SCDF
- Acetaminophen / chlorpheniramine maleate / dextromethorphan hydrobromide / pseudoephedrine hydrochloride Oral Solution 2647468 SCDFP
- Acetaminophen / chlorpheniramine / dextromethorphan / pseudoephedrine Oral Liquid Product 1154909 SCDG
- Acetaminophen / chlorpheniramine / dextromethorphan / pseudoephedrine Oral Product 1155230 SCDG
- Acetaminophen / chlorpheniramine maleate / dextromethorphan hydrobromide / pseudoephedrine hydrochloride Oral Liquid Product 2659786 SCDGP
- Acetaminophen / chlorpheniramine maleate / dextromethorphan hydrobromide / pseudoephedrine hydrochloride Oral Product 2663114 SCDGP
- Oral Solution 316968 DF
- Oral Liquid Product 1151137 DFG
- +1 more in this family
Clinical & branded drugs 4

Ingredient + strength + dose form. These are the concepts real FDA products actually carry.
- Acetaminophen 33.3 MG/ML 328877 SCDC
- Chlorpheniramine maleate 0.133 MG/ML 1046383 SCDC
- Dextromethorphan hydrobromide 1 MG/ML 1020137 SCDC
- Pseudoephedrine hydrochloride 2 MG/ML 996999 SCDC

Showing up to 8 concepts per family — 20 of 21 stored related concepts drawn.

These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

Acetaminophen 33.3 MG/ML SCDC · 328877
Chlorpheniramine maleate 0.133 MG/ML SCDC · 1046383
Dextromethorphan hydrobromide 1 MG/ML SCDC · 1020137
Pseudoephedrine hydrochloride 2 MG/ML SCDC · 996999
Acetaminophen / chlorpheniramine / dextromethorphan / pseudoephedrine Oral Solution SCDF · 374770
Acetaminophen / chlorpheniramine maleate / dextromethorphan hydrobromide / pseudoephedrine hydrochloride Oral Solution SCDFP · 2647468
Acetaminophen / chlorpheniramine / dextromethorphan / pseudoephedrine Oral Liquid Product SCDG · 1154909
Acetaminophen / chlorpheniramine / dextromethorphan / pseudoephedrine Oral Product SCDG · 1155230
Acetaminophen / chlorpheniramine maleate / dextromethorphan hydrobromide / pseudoephedrine hydrochloride Oral Liquid Product SCDGP · 2659786
Acetaminophen / chlorpheniramine maleate / dextromethorphan hydrobromide / pseudoephedrine hydrochloride Oral Product SCDGP · 2663114

📦 FDA Products & Package NDCs

1 product · 1 package NDC

1 package NDC map to RxCUI 2049283 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.

Package NDC	Package	Brand / generic name	Labeler	Marketing start
00067-0114-01	1 BOTTLE in 1 CARTON (0067-0114-01) / 237 mL in 1 BOTTLE	Theraflu-D Flu Relief Max Strength plus Nasal Decongestant Nighttime	Haleon US Holdings LLC	2024-06-19

Observed labelers: Haleon US Holdings LLC (1) — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7

openFDA export observedJul 14, 2026

RxNorm release07/06/2026

Methodology2026-07-full-catalog-v1

A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.

This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.