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Acetaminophen 325 MG / dextromethorphan hydrobromide 10 MG / guaifenesin 200 MG Oral Capsu... — RxCUI 2377385

Name: Acetaminophen 325 MG / dextromethorphan hydrobromide 10 MG / guaifenesin 200 MG Oral… (RxCUI 2377385)
Creator: Brian Staiger, PharmD

RxNorm drug concept · Semantic clinical drug

RxCUI 2377385 Semantic clinical drug · SCD ● Current RxNorm concept 2 FDA products 4 package NDCs Snapshot Jul 14, 2026

This page is curated, coded, and maintained by Dr. Brian Staiger, PharmD

Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI2377385

Official nameAcetaminophen 325 MG / dextromethorphan hydrobromide 10 MG / guaifenesin 200 MG Oral Capsule

Concept typeSemantic clinical drug (SCD)

RxNorm statusCurrent RxNorm concept

Also known asAPAP 325 MG / dextromethorphan hydrobromide 10 MG / guaifenesin 200 MG Oral Capsule; acetaminophen 325 MG / dextromethorphan HBr 10 MG / guaiFENesin 200 MG Oral Capsule

FDA products mapped2

Package NDCs mapped4

RxNorm release07/06/2026

Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Acetaminophen Injection: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist

Great question. The IV form is used when you can't take medication by mouth — for example, after surgery, if you're nauseated, or if you need faster, more reliable absorption. It d...
Why am I getting acetaminophen through an IV instead of just taking a pill?
Yes, Acetaminophen Injection is approved for children — for pain relief in kids 2 years and older, and for fever reduction in patients of all ages, including premature newborns bor...
The most important things to watch for are signs of a serious allergic reaction — swelling of your face, mouth, or throat, trouble breathing, or hives — and any new skin rash. Eith...

📖 Read our full Acetaminophen Injection guide →

🕸️ Concept Web — How Acetaminophen 325 MG / dextromethorphan hydrobro... Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.

This page's concept Acetaminophen 325 MG / dextromethorphan hydrobromide 10 MG / guaifenesin 200 MG Oral Capsule RxCUI 2377385 Semantic clinical drug · SCD

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

Ingredients 5

The active substance itself — no strength, form, or brand attached yet.
- Acetaminophen 161 IN
- Dextromethorphan 3289 IN
- Guaifenesin 5032 IN
- Acetaminophen / dextromethorphan / guaifenesin 689775 MIN
- Dextromethorphan hydrobromide 102490 PIN
Dose forms 9

The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.
- Acetaminophen / dextromethorphan / guaifenesin Oral Capsule 2377384 SCDF
- Acetaminophen / dextromethorphan hydrobromide / guaifenesin Oral Capsule 2648508 SCDFP
- Acetaminophen / dextromethorphan / guaifenesin Oral Product 1155913 SCDG
- Acetaminophen / dextromethorphan / guaifenesin Pill 1155914 SCDG
- Acetaminophen / dextromethorphan hydrobromide / guaifenesin Oral Product 2662330 SCDGP
- Acetaminophen / dextromethorphan hydrobromide / guaifenesin Pill 2662448 SCDGP
- Oral Capsule 316965 DF
- Oral Product 1151131 DFG
- +1 more in this family
Clinical & branded drugs 3

Ingredient + strength + dose form. These are the concepts real FDA products actually carry.
- Acetaminophen 325 MG 315263 SCDC
- Dextromethorphan hydrobromide 10 MG 1014455 SCDC
- Guaifenesin 200 MG 317384 SCDC

Showing up to 8 concepts per family — 16 of 17 stored related concepts drawn.

These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

Acetaminophen 325 MG SCDC · 315263
Dextromethorphan hydrobromide 10 MG SCDC · 1014455
Guaifenesin 200 MG SCDC · 317384
Acetaminophen / dextromethorphan / guaifenesin Oral Capsule SCDF · 2377384
Acetaminophen / dextromethorphan hydrobromide / guaifenesin Oral Capsule SCDFP · 2648508
Acetaminophen / dextromethorphan / guaifenesin Oral Product SCDG · 1155913
Acetaminophen / dextromethorphan / guaifenesin Pill SCDG · 1155914
Acetaminophen / dextromethorphan hydrobromide / guaifenesin Oral Product SCDGP · 2662330
Acetaminophen / dextromethorphan hydrobromide / guaifenesin Pill SCDGP · 2662448

📦 FDA Products & Package NDCs

2 products · 4 package NDCs

4 package NDCs map to RxCUI 2377385 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.

Package NDC	Package	Brand / generic name	Labeler	Marketing start
11673-0844-24	24 BLISTER PACK in 1 CARTON (11673-844-24) / 1 KIT in 1 BLI...	Daytime Nighttime Severe Cold and Flu	TARGET CORP	2024-07-01
35916-0184-02	3000 CAPSULE, LIQUID FILLED in 1 POUCH (35916-0184-2)	Acetaminophen, Dextromethorphan HBr ,Guaifenesin	Softgel Healthcare Pvt Ltd	2025-05-17
35916-0184-03	2 POUCH in 1 BOX (35916-0184-3) / 2000 CAPSULE, LIQUID FILL...	Acetaminophen, Dextromethorphan HBr ,Guaifenesin	Softgel Healthcare Pvt Ltd	2025-09-25
35916-0184-04	2 BAG in 1 BOX (35916-0184-4) / 1500 CAPSULE, LIQUID FILLED...	Acetaminophen, Dextromethorphan HBr ,Guaifenesin	Softgel Healthcare Pvt Ltd	2026-01-16

Observed labelers: Softgel Healthcare Pvt Ltd (3) · TARGET CORP (1) — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7

openFDA export observedJul 14, 2026

RxNorm release07/06/2026

Methodology2026-07-full-catalog-v1

A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.

This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.