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Acetaminophen 250 MG / ibuprofen 125 MG Oral Tablet — RxCUI 2387532

RxNorm drug concept · Semantic clinical drug
RxCUI 2387532 Semantic clinical drug · SCD ● Current RxNorm concept 69 FDA products 200 package NDCs Snapshot Jul 14, 2026

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Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI2387532
Official nameAcetaminophen 250 MG / ibuprofen 125 MG Oral Tablet
Concept typeSemantic clinical drug (SCD)
RxNorm statusCurrent RxNorm concept
Also known asAPAP 250 MG / ibuprofen 125 MG Oral Tablet
FDA products mapped69
Package NDCs mapped200
Reported Medicaid activity (SDUD)15 prescriptions · 1 state & territory Medicaid programs · latest period Q4 2025
RxNorm release07/06/2026
Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Acetaminophen Injection: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist
  • It treats mild to moderate pain, and moderate to severe pain when used with opioid medicines. It also lowers fever. It is given through a vein in a healthcare setting.
  • What is Acetaminophen Injection used for?
  • It is given as an IV infusion over 15 minutes by a healthcare professional. Your dose depends on your age and weight. Your care team follows the label and your prescriber's orders.
  • The most common are nausea and vomiting. Adults may also get headache or trouble sleeping. Children may have constipation or itching.
📖 Read our full Acetaminophen Injection guide →

🕸️ Concept Web — How Acetaminophen 250 MG / ibuprofen 125 MG Oral Tab... Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.
This page's concept Acetaminophen 250 MG / ibuprofen 125 MG Oral Tablet RxCUI 2387532

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

  1. Ingredients 3

    The active substance itself — no strength, form, or brand attached yet.

    • Acetaminophen 161
    • Ibuprofen 5640
    • Acetaminophen / ibuprofen 818102
  2. Dose forms 6

    The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.

    • Acetaminophen / ibuprofen Oral Tablet 372452
    • Acetaminophen / ibuprofen Oral Product 1151552
    • Acetaminophen / ibuprofen Pill 1151553
    • Oral Tablet 317541
    • Oral Product 1151131
    • Pill 1151133
  3. Clinical & branded drugs 2

    Ingredient + strength + dose form. These are the concepts real FDA products actually carry.

    • Acetaminophen 250 MG 315259
    • Ibuprofen 125 MG 2387531

Showing up to 8 concepts per family — 11 of 11 stored related concepts drawn.
These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

  • Acetaminophen 250 MG SCDC · 315259
  • Ibuprofen 125 MG SCDC · 2387531
  • Acetaminophen / ibuprofen Oral Tablet SCDF · 372452
  • Acetaminophen / ibuprofen Oral Product SCDG · 1151552
  • Acetaminophen / ibuprofen Pill SCDG · 1151553

📦 FDA Products & Package NDCs

69 products · 200 package NDCs
200 package NDCs map to RxCUI 2387532 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.
Package NDC Package Brand / generic name Labeler Marketing start
00113-5299-16 1 BOTTLE in 1 CARTON (0113-5299-16) / 144 TABLET, FILM COAT... Good Sense Dual Action Back Pain L. Perrigo Company 2024-03-15
00113-5299-23 1 BOTTLE in 1 CARTON (0113-5299-23) / 72 TABLET, FILM COATE... Good Sense Dual Action Back Pain L. Perrigo Company 2024-03-07
00113-5299-68 1 BOTTLE in 1 CARTON (0113-5299-68) / 36 TABLET, FILM COATE... Good Sense Dual Action Back Pain L. Perrigo Company 2024-03-07
00113-5299-89 1 BOTTLE in 1 CARTON (0113-5299-89) / 18 TABLET, FILM COATE... Good Sense Dual Action Back Pain L. Perrigo Company 2024-03-15
00113-5300-16 1 BOTTLE in 1 CARTON (0113-5300-16) / 144 TABLET, FILM COAT... good sense dual action L Perrigo Company 2023-03-01
00113-5300-68 1 BOTTLE in 1 CARTON (0113-5300-68) / 36 TABLET, FILM COATE... good sense dual action L Perrigo Company 2023-03-01
00363-4081-78 1 BOTTLE in 1 CARTON (0363-4081-78) / 80 TABLET, FILM COATE... Acetaminophen and Ibuprofen WALGREEN COMPANY 2024-12-04
00363-5220-01 1 BOTTLE in 1 CARTON (0363-5220-01) / 216 TABLET, FILM COAT... dual pain reliever Walgreen Company 2023-12-11
00363-5220-16 1 BOTTLE in 1 CARTON (0363-5220-16) / 144 TABLET, FILM COAT... dual pain reliever Walgreen Company 2023-12-11
00363-5220-23 1 BOTTLE in 1 CARTON (0363-5220-23) / 72 TABLET, FILM COATE... dual pain reliever Walgreen Company 2023-03-10
00363-5220-68 1 BOTTLE in 1 CARTON (0363-5220-68) / 36 TABLET, FILM COATE... dual pain reliever Walgreen Company 2023-03-10
00363-6199-23 1 BOTTLE in 1 CARTON (0363-6199-23) / 72 TABLET, FILM COATE... Dual Back Pain Reliever Walgreen Company 2024-02-16
00363-9131-16 216 TABLET in 1 BOTTLE (0363-9131-16) Acetaminophen and Ibuprofen WALGREENS 2023-07-19
00363-9131-44 144 TABLET in 1 BOTTLE (0363-9131-44) Acetaminophen and Ibuprofen WALGREENS 2023-07-19
00536-1376-36 36 TABLET in 1 BOTTLE (0536-1376-36) Acetaminophen and Ibuprofen RUGBY LABORATORIES 2023-07-15
00573-0145-02 2 TABLET, FILM COATED in 1 POUCH (0573-0145-02) ADVIL DUAL ACTION WITH ACETAMINOPHEN Back Pain Haleon US Holdings LLC 2023-01-16
00573-0145-18 1 BOTTLE in 1 CARTON (0573-0145-18) / 18 TABLET, FILM COATE... ADVIL DUAL ACTION WITH ACETAMINOPHEN Back Pain Haleon US Holdings LLC 2023-01-16
00573-0145-72 1 BOTTLE in 1 CARTON (0573-0145-72) / 72 TABLET, FILM COATE... ADVIL DUAL ACTION WITH ACETAMINOPHEN Back Pain Haleon US Holdings LLC 2023-01-16
00573-0145-89 1 BOTTLE in 1 CARTON (0573-0145-89) / 144 TABLET, FILM COAT... ADVIL DUAL ACTION WITH ACETAMINOPHEN Back Pain Haleon US Holdings LLC 2023-01-16
00573-0145-99 3000 POUCH in 1 CASE (0573-0145-99) / 2 TABLET, FILM COATED... ADVIL DUAL ACTION WITH ACETAMINOPHEN Back Pain Haleon US Holdings LLC 2023-01-16
00573-0147-09 8 TABLET, FILM COATED in 1 BOTTLE (0573-0147-09) ADVIL DUAL ACTION WITH ACETAMINOPHEN Haleon US Holdings LLC 2023-05-15
00573-0147-18 1 BOTTLE in 1 CARTON (0573-0147-18) / 18 TABLET, FILM COATE... ADVIL DUAL ACTION WITH ACETAMINOPHEN Haleon US Holdings LLC 2020-07-27
00573-0147-24 1 BOTTLE in 1 CARTON (0573-0147-24) / 24 TABLET, FILM COATE... ADVIL DUAL ACTION WITH ACETAMINOPHEN Haleon US Holdings LLC 2021-09-06
00573-0147-36 1 BOTTLE in 1 CARTON (0573-0147-36) / 36 TABLET, FILM COATE... ADVIL DUAL ACTION WITH ACETAMINOPHEN Haleon US Holdings LLC 2020-07-27
00573-0147-72 1 BOTTLE in 1 CARTON (0573-0147-72) / 72 TABLET, FILM COATE... ADVIL DUAL ACTION WITH ACETAMINOPHEN Haleon US Holdings LLC 2020-07-27
00573-0147-86 1 BOTTLE in 1 CARTON (0573-0147-86) / 216 TABLET, FILM COAT... ADVIL DUAL ACTION WITH ACETAMINOPHEN Haleon US Holdings LLC 2020-07-27
00573-0147-90 1 BOTTLE in 1 CARTON (0573-0147-90) / 90 TABLET, FILM COATE... ADVIL DUAL ACTION WITH ACETAMINOPHEN Haleon US Holdings LLC 2024-04-08
00573-0147-91 3000 POUCH in 1 CASE (0573-0147-91) / 2 TABLET, FILM COATED... ADVIL DUAL ACTION WITH ACETAMINOPHEN Haleon US Holdings LLC 2023-05-15
00573-0147-93 1 BOTTLE in 1 CARTON (0573-0147-93) / 162 TABLET, FILM COAT... ADVIL DUAL ACTION WITH ACETAMINOPHEN Haleon US Holdings LLC 2024-04-09
00573-0147-94 1 BOTTLE in 1 CARTON (0573-0147-94) / 144 TABLET, FILM COAT... ADVIL DUAL ACTION WITH ACETAMINOPHEN Haleon US Holdings LLC 2020-07-27
00573-0147-95 50 POUCH in 1 CARTON (0573-0147-95) / 2 TABLET, FILM COATED... ADVIL DUAL ACTION WITH ACETAMINOPHEN Haleon US Holdings LLC 2020-07-27
00573-0147-97 240 TABLET, FILM COATED in 1 BOTTLE (0573-0147-97) ADVIL DUAL ACTION WITH ACETAMINOPHEN Haleon US Holdings LLC 2025-03-15
11673-0924-75 1 BOTTLE in 1 CARTON (11673-924-75) / 72 TABLET in 1 BOTTLE Dual Action Pain Relief TARGET CORPORATION 2023-07-11
11822-1131-04 144 TABLET in 1 BOTTLE (11822-1131-4) Acetaminophen and Ibuprofen (NSAID) RITE AID 2023-07-21
11822-1131-06 216 TABLET in 1 BOTTLE (11822-1131-6) Acetaminophen and Ibuprofen (NSAID) RITE AID 2023-07-21
11822-5777-00 1 BOTTLE in 1 CARTON (11822-5777-0) / 36 TABLET, FILM COATE... dual action Rite Aid Corporation 2023-05-24
11822-5777-01 1 BOTTLE in 1 CARTON (11822-5777-1) / 72 TABLET, FILM COATE... dual action Rite Aid Corporation 2023-05-24
11822-5777-02 1 BOTTLE in 1 CARTON (11822-5777-2) / 18 TABLET, FILM COATE... dual action Rite Aid Corporation 2023-05-24
21130-0716-08 1 BOTTLE in 1 CARTON (21130-716-08) / 18 TABLET in 1 BOTTLE Dual Action BETTER LIVING BRANDS, LLC 2023-08-30
21130-0716-75 1 BOTTLE in 1 CARTON (21130-716-75) / 72 TABLET in 1 BOTTLE Dual Action BETTER LIVING BRANDS, LLC 2023-08-30
25000-0080-07 1 BOTTLE in 1 CARTON (25000-080-07) / 90 TABLET, FILM COATE... Acetaminophen 250 mg and Ibuprofen 125 mg MARKSANS PHARMA LIMITED 2023-07-11
25000-0080-72 1 BOTTLE in 1 CARTON (25000-080-72) / 18 TABLET, FILM COATE... Acetaminophen 250 mg and Ibuprofen 125 mg MARKSANS PHARMA LIMITED 2023-07-11
25000-0080-74 288 TABLET, FILM COATED in 1 BOTTLE (25000-080-74) Acetaminophen 250 mg and Ibuprofen 125 mg MARKSANS PHARMA LIMITED 2023-07-11
30142-0720-23 1 BOTTLE in 1 CARTON (30142-720-23) / 72 TABLET, FILM COATE... acetaminophen and ibuprofen Kroger Company 2023-05-16
41163-0103-68 1 BOTTLE in 1 CARTON (41163-103-68) / 36 TABLET, FILM COATE... equaline dual action pain reliever United Natural Foods, Inc. dba UNFI 2024-03-21
41163-0103-89 1 BOTTLE in 1 CARTON (41163-103-89) / 18 TABLET, FILM COATE... equaline dual action pain reliever United Natural Foods, Inc. dba UNFI 2024-03-21
41226-0716-49 1 BOTTLE in 1 CARTON (41226-716-49) / 144 TABLET in 1 BOTTL... Dual Action KROGER COMPANY 2023-07-11
42507-0540-72 1 BOTTLE in 1 CARTON (42507-540-72) / 72 TABLET, FILM COATE... DUAL ACTION HyVee Inc 2026-03-18
43598-0052-05 500 TABLET, FILM COATED in 1 BOTTLE (43598-052-05) Acetaminophen 250 mg and Ibuprofen 125 mg Dr. Reddy's Labortories Inc 2025-02-19
43598-0052-14 144 TABLET, FILM COATED in 1 BOTTLE (43598-052-14) Acetaminophen 250 mg and Ibuprofen 125 mg Dr. Reddy's Labortories Inc 2025-02-19
Observed labelers: Aurohealth LLC (59) · Haleon US Holdings LLC (17) · Dolgencorp Inc (7) · GLENMARK THERAPEUTICS INC., USA (7) · Walgreen Company (6) · Bionpharma Inc. (5) · +43 more — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7
openFDA export observedJul 14, 2026
RxNorm release07/06/2026
Methodology2026-07-full-catalog-v1
  • A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
  • Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
  • Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
  • Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.
This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.