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0.5 ML etanercept 50 MG/ML Injection [Enbrel] — RxCUI 2392142

RxNorm drug concept · Semantic branded drug
RxCUI 2392142 Semantic branded drug · SBD ● Current RxNorm concept 5 FDA products 14 package NDCs Snapshot Jul 14, 2026

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Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI2392142
Official name0.5 ML etanercept 50 MG/ML Injection [Enbrel]
Concept typeSemantic branded drug (SBD)
RxNorm statusCurrent RxNorm concept
Also known as0.5 ML Enbrel 50 MG/ML Injection; Enbrel 25 MG in 0.5 mL Injection; Enbrel 25 MG per 0.5 mL Injection
FDA products mapped5
Package NDCs mapped14
Reported Medicaid activity (SDUD)136,826 prescriptions · 52 state & territory Medicaid programs · latest period Q4 2025
RxNorm release07/06/2026
Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Etanercept Injection: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist
  • Enbrel works by blocking a protein called TNF, which is overproduced in conditions like rheumatoid arthritis and psoriasis and drives inflammation and tissue damage. It needs to be...
  • What exactly does Enbrel do, and why do I need an injection instead of a pill?
  • The most common side effects are injection site reactions — redness, itching, or mild swelling where you give the shot — and upper respiratory infections like colds or sinusitis. T...
  • What side effects are most likely, and which ones should make me call my doctor right away?
📖 Read our full Etanercept Injection guide →

🕸️ Concept Web — How 0.5 ML etanercept 50 MG/ML Injection [Enbrel] Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.
This page's concept 0.5 ML etanercept 50 MG/ML Injection [Enbrel] RxCUI 2392142

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

  1. Ingredients 1

    The active substance itself — no strength, form, or brand attached yet.

    • Etanercept 214555
  2. Brand names 1

    The same medicine's trade names. A brand name alone says nothing about strength or form.

    • Enbrel 216891
  3. Dose forms 6

    The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.

    • Etanercept Injection 2392139
    • Etanercept Injectable Product 1156809
    • Etanercept Injection [Enbrel] 2392141
    • Enbrel Injectable Product 1175957
    • Injection 1649574
    • Injectable Product 1151126
  4. Clinical & branded drugs 3

    Ingredient + strength + dose form. These are the concepts real FDA products actually carry.

Showing up to 8 concepts per family — 11 of 11 stored related concepts drawn.
These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

Brand-Name Concepts

  • Etanercept 50 MG/ML [Enbrel] SBDC · 582672
  • Etanercept Injection [Enbrel] SBDF · 2392141
  • Enbrel Injectable Product SBDG · 1175957
  • Enbrel BN · 216891

📦 FDA Products & Package NDCs

5 products · 14 package NDCs
14 package NDCs map to RxCUI 2392142 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.
Package NDC Package Brand / generic name Labeler Marketing start
58406-0010-04 4 SYRINGE in 1 CARTON (58406-010-04) / .5 mL in 1 SYRINGE (... ENBREL Immunex Corporation 2019-06-07
58406-0010-96 1 SYRINGE in 1 CARTON (58406-010-96) / .5 mL in 1 SYRINGE ENBREL Immunex Corporation 2019-06-07
58406-0021-04 4 SYRINGE in 1 CARTON (58406-021-04) / 1 mL in 1 SYRINGE (5... ENBREL Immunex Corporation 2019-06-07
58406-0021-96 1 SYRINGE in 1 CARTON (58406-021-96) / 1 mL in 1 SYRINGE ENBREL Immunex Corporation 2019-06-07
58406-0032-04 4 SYRINGE in 1 CARTON (58406-032-04) / 1 mL in 1 SYRINGE (5... ENBREL Immunex Corporation 2019-06-07
58406-0032-90 1 SYRINGE in 1 CARTON (58406-032-90) / 1 mL in 1 SYRINGE ENBREL Immunex Corporation 2019-06-07
58406-0032-96 1 SYRINGE in 1 CARTON (58406-032-96) / 1 mL in 1 SYRINGE ENBREL Immunex Corporation 2019-06-07
58406-0044-04 4 CARTRIDGE in 1 CARTON (58406-044-04) / 1 mL in 1 CARTRIDG... ENBREL Immunex Corporation 2019-06-07
58406-0044-24 4 CARTRIDGE in 1 CARTON (58406-044-24) / 1 mL in 1 CARTRIDG... ENBREL Immunex Corporation 2019-06-07
58406-0044-90 1 CARTRIDGE in 1 CARTON (58406-044-90) / 1 mL in 1 CARTRIDG... ENBREL Immunex Corporation 2019-06-07
58406-0044-96 1 CARTRIDGE in 1 CARTON (58406-044-96) / 1 mL in 1 CARTRIDG... ENBREL Immunex Corporation 2019-06-07
58406-0055-04 4 VIAL, SINGLE-DOSE in 1 CARTON (58406-055-04) / .5 mL in 1... ENBREL Immunex Corporation 2020-03-05
58406-0055-90 1 VIAL, SINGLE-DOSE in 1 CARTON (58406-055-90) / .5 mL in 1... ENBREL Immunex Corporation 2020-03-05
58406-0055-96 1 VIAL, SINGLE-DOSE in 1 CARTON (58406-055-96) / .5 mL in 1... ENBREL Immunex Corporation 2020-03-05
Observed labelers: Immunex Corporation (14) — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7
openFDA export observedJul 14, 2026
RxNorm release07/06/2026
Methodology2026-07-full-catalog-v1
  • A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
  • Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
  • Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
  • Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.
This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

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Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.