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Insulin lispro 25 UNT/ML / insulin lispro protamine, human 75 UNT/ML Injectable Suspension — RxCUI 259111

RxNorm drug concept · Semantic clinical drug
RxCUI 259111 Semantic clinical drug · SCD ● Current RxNorm concept 2 FDA products 3 package NDCs Snapshot Jul 14, 2026

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Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI259111
Official nameInsulin lispro 25 UNT/ML / insulin lispro protamine, human 75 UNT/ML Injectable Suspension
Concept typeSemantic clinical drug (SCD)
RxNorm statusCurrent RxNorm concept
Also known asinsulin analog, lispro mixed 75/25 100 UNT/ML Injectable Suspension; insulin lispro protamine / insulin lispro 75/25 Injectable Suspension
FDA products mapped2
Package NDCs mapped3
Reported Medicaid activity (SDUD)21,046 prescriptions · 42 state & territory Medicaid programs · latest period Q4 2025
RxNorm release07/06/2026
Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Insulin Lispro Injection: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist
  • Insulin lispro is a fast-acting insulin that helps your body manage blood sugar around mealtimes. It works by helping your muscles and fat cells absorb glucose from your blood, whi...
  • What exactly does insulin lispro do, and why did my doctor prescribe it?
  • For subcutaneous injections, you should inject insulin lispro within 15 minutes before a meal or immediately after a meal. Because it acts quickly, timing really matters — injectin...
  • When exactly should I inject this insulin — before or after I eat?
📖 Read our full Insulin Lispro Injection guide →

🕸️ Concept Web — How Insulin lispro 25 UNT/ML / insulin lispro protam... Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.
This page's concept Insulin lispro 25 UNT/ML / insulin lispro protamine, human 75 UNT/ML Injectable Suspension RxCUI 259111

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

  1. Ingredients 3

    The active substance itself — no strength, form, or brand attached yet.

    • Insulin lispro 86009
    • Insulin lispro protamine, human 314684
    • Insulin lispro / insulin lispro protamine, human 816726
  2. Brand names 1

    The same medicine's trade names. A brand name alone says nothing about strength or form.

    • Humalog Mix 261542
  3. Dose forms 6

    The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.

    • Insulin lispro / insulin lispro protamine, human Injectable Suspension 378966
    • Insulin lispro / insulin lispro protamine, human Injectable Product 1157460
    • Insulin lispro / insulin lispro protamine, human Injectable Suspension [Humalog Mix] 731280
    • Humalog Mix Injectable Product 1171291
    • Injectable Suspension 316950
    • Injectable Product 1151126
  4. Clinical & branded drugs 4

    Ingredient + strength + dose form. These are the concepts real FDA products actually carry.

Showing up to 8 concepts per family — 14 of 14 stored related concepts drawn.
These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

  • Insulin lispro 25 UNT/ML SCDC · 343263
  • Insulin lispro protamine, human 75 UNT/ML SCDC · 343264
  • Insulin lispro / insulin lispro protamine, human Injectable Suspension SCDF · 378966
  • Insulin lispro / insulin lispro protamine, human Injectable Product SCDG · 1157460

Brand-Name Concepts

📦 FDA Products & Package NDCs

2 products · 3 package NDCs
3 package NDCs map to RxCUI 259111 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.
Package NDC Package Brand / generic name Labeler Marketing start
00002-7511-01 1 VIAL, MULTI-DOSE in 1 CARTON (0002-7511-01) / 10 mL in 1... Humalog Mix75/25 Eli Lilly and Company 2000-10-10
00002-8797-59 5 SYRINGE in 1 CARTON (0002-8797-59) / 3 mL in 1 SYRINGE (0... Humalog Mix75/25 KwikPen Eli Lilly and Company 2008-01-16
00002-8797-61 1 SYRINGE in 1 CARTON (0002-8797-61) / 3 mL in 1 SYRINGE Humalog Mix75/25 KwikPen Eli Lilly and Company 2017-10-01
Observed labelers: Eli Lilly and Company (3) — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

💲 Pricing (NADAC)

NADAC is CMS's National Average Drug Acquisition Cost — roughly what pharmacies pay to buy the drug. It is an acquisition benchmark, not your copay.
Per ml · median
$9.1628
Range $8.1540–$10.1715 · middle 50% $8.6584–$9.6671 · 2 NDCs
Latest compatible distributions from the CMS NADAC file · dataset watermark 2026-07-10. Prices vary by package and pharmacy; a distribution is shown instead of one misleading number. Rows the dataset is silent on carry no price. No zero-cost conclusion should be drawn.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7
openFDA export observedJul 14, 2026
RxNorm release07/06/2026
Methodology2026-07-full-catalog-v1
  • A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
  • Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
  • Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
  • Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.
This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.