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Acetaminophen 162.5 MG / chlorpheniramine maleate 2 MG / dextromethorphan hydrobromide 5 M... — RxCUI 2678231

RxNorm drug concept · Semantic clinical drug
RxCUI 2678231 Semantic clinical drug · SCD ● Current RxNorm concept 2 FDA products 3 package NDCs Snapshot Jul 14, 2026

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Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI2678231
Official nameAcetaminophen 162.5 MG / chlorpheniramine maleate 2 MG / dextromethorphan hydrobromide 5 MG Chewable Tablet
Concept typeSemantic clinical drug (SCD)
RxNorm statusCurrent RxNorm concept
Also known asAPAP 162.5 MG / chlorpheniramine maleate 2 MG / dextromethorphan hydrobromide 5 MG Chewable Tablet
FDA products mapped2
Package NDCs mapped3
RxNorm release07/06/2026
Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Acetaminophen Injection: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist
  • It treats mild to moderate pain, and moderate to severe pain when used with opioid medicines. It also lowers fever. It is given through a vein in a healthcare setting.
  • What is Acetaminophen Injection used for?
  • It is given as an IV infusion over 15 minutes by a healthcare professional. Your dose depends on your age and weight. Your care team follows the label and your prescriber's orders.
  • The most common are nausea and vomiting. Adults may also get headache or trouble sleeping. Children may have constipation or itching.
📖 Read our full Acetaminophen Injection guide →

🕸️ Concept Web — How Acetaminophen 162.5 MG / chlorpheniramine maleat... Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.
This page's concept Acetaminophen 162.5 MG / chlorpheniramine maleate 2 MG / dextromethorphan hydrobromide 5 MG Chewable Tablet RxCUI 2678231

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

  1. Ingredients 6

    The active substance itself — no strength, form, or brand attached yet.

    • Acetaminophen 161
    • Chlorpheniramine 2400
    • Dextromethorphan 3289
    • Acetaminophen / chlorpheniramine / dextromethorphan 1007587
    • Chlorpheniramine maleate 142429
    • Dextromethorphan hydrobromide 102490
  2. Dose forms 12

    The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.

    • Acetaminophen / chlorpheniramine / dextromethorphan Chewable Tablet 2678227
    • Acetaminophen / chlorpheniramine maleate / dextromethorphan hydrobromide Chewable Tablet 2678229
    • Acetaminophen / chlorpheniramine / dextromethorphan Chewable Product 2678226
    • Acetaminophen / chlorpheniramine / dextromethorphan Oral Product 1155233
    • Acetaminophen / chlorpheniramine / dextromethorphan Pill 1155234
    • Acetaminophen / chlorpheniramine maleate / dextromethorphan hydrobromide Chewable Product 2678228
    • Acetaminophen / chlorpheniramine maleate / dextromethorphan hydrobromide Oral Product 2659663
    • Acetaminophen / chlorpheniramine maleate / dextromethorphan hydrobromide Pill 2663603
    • +4 more in this family
  3. Clinical & branded drugs 3

    Ingredient + strength + dose form. These are the concepts real FDA products actually carry.

    • Acetaminophen 162.5 MG 1242746
    • Chlorpheniramine maleate 2 MG 999433
    • Dextromethorphan hydrobromide 5 MG 998603

Showing up to 8 concepts per family — 17 of 21 stored related concepts drawn.
These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

  • Acetaminophen 162.5 MG SCDC · 1242746
  • Chlorpheniramine maleate 2 MG SCDC · 999433
  • Dextromethorphan hydrobromide 5 MG SCDC · 998603
  • Acetaminophen / chlorpheniramine / dextromethorphan Chewable Tablet SCDF · 2678227
  • Acetaminophen / chlorpheniramine maleate / dextromethorphan hydrobromide Chewable Tablet SCDFP · 2678229
  • Acetaminophen / chlorpheniramine / dextromethorphan Chewable Product SCDG · 2678226
  • Acetaminophen / chlorpheniramine / dextromethorphan Oral Product SCDG · 1155233
  • Acetaminophen / chlorpheniramine / dextromethorphan Pill SCDG · 1155234
  • Acetaminophen / chlorpheniramine maleate / dextromethorphan hydrobromide Chewable Product SCDGP · 2678228
  • Acetaminophen / chlorpheniramine maleate / dextromethorphan hydrobromide Oral Product SCDGP · 2659663

📦 FDA Products & Package NDCs

2 products · 3 package NDCs
3 package NDCs map to RxCUI 2678231 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.
Package NDC Package Brand / generic name Labeler Marketing start
00280-0151-01 3 BLISTER PACK in 1 CARTON (0280-0151-01) / 8 TABLET, CHEWA... Alka-Seltzer Plus Cold and Flu FizzyChews Bayer HealthCare LLC. 2024-04-01
00280-0151-02 2 BLISTER PACK in 1 CARTON (0280-0151-02) / 8 TABLET, CHEWA... Alka-Seltzer Plus Cold and Flu FizzyChews Bayer HealthCare LLC. 2024-04-01
00280-8269-24 3 BLISTER PACK in 1 CARTON (0280-8269-24) / 8 TABLET, CHEWA... ALKA SELTZER COLD Cold and Flu Severe Fast Chewables Bayer HealthCare LLC. 2026-06-01
Observed labelers: Bayer HealthCare LLC. (3) — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7
openFDA export observedJul 14, 2026
RxNorm release07/06/2026
Methodology2026-07-full-catalog-v1
  • A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
  • Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
  • Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
  • Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.
This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.