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Acetaminophen 32 MG/ML / diphenhydramine hydrochloride 1.25 MG/ML Oral Solution — RxCUI 2683420

Name: Acetaminophen 32 MG/ML / diphenhydramine hydrochloride 1.25 MG/ML Oral Solution (RxCUI 2683420)
Creator: Brian Staiger, PharmD

RxNorm drug concept · Semantic clinical drug

RxCUI 2683420 Semantic clinical drug · SCD ● Current RxNorm concept 1 FDA product 2 package NDCs Snapshot Jul 14, 2026

This page is curated, coded, and maintained by Dr. Brian Staiger, PharmD

Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI2683420

Official nameAcetaminophen 32 MG/ML / diphenhydramine hydrochloride 1.25 MG/ML Oral Solution

Concept typeSemantic clinical drug (SCD)

RxNorm statusCurrent RxNorm concept

Also known asAPAP 32 MG/ML / diphenhydramine hydrochloride 1.25 MG/ML Oral Solution; acetaminophen 320 MG / diphenhydrAMINE HCl 12.5 MG in 10 mL Oral Solution; acetaminophen 320 MG / diphenhydramine HCl 12.5 MG per 10 mL Oral Solution

FDA products mapped1

Package NDCs mapped2

RxNorm release07/06/2026

Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Diphenhydramine Topical: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist

It gives temporary relief of pain and itching on the skin. That includes minor burns, minor cuts or scrapes, insect bites, minor skin irritations, and rashes from poison ivy, oak o...
Adults and children 2 and older can apply it to the affected area no more than 3 to 4 times a day. Don't use it more often than directed. For a child under 2, check with a doctor f...
No. Don't use it on large areas of the body or on broken, blistered or oozing skin. Also avoid it on chicken pox or sunburn.
Can I put it on a large area or on blistered skin?

📖 Read our full Diphenhydramine Topical guide →

🕸️ Concept Web — How Acetaminophen 32 MG/ML / diphenhydramine hydroch... Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.

This page's concept Acetaminophen 32 MG/ML / diphenhydramine hydrochloride 1.25 MG/ML Oral Solution RxCUI 2683420 Semantic clinical drug · SCD

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

Ingredients 4

The active substance itself — no strength, form, or brand attached yet.
- Acetaminophen 161 IN
- Diphenhydramine 3498 IN
- Acetaminophen / diphenhydramine 214181 MIN
- Diphenhydramine hydrochloride 1362 PIN
Dose forms 9

The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.
- Acetaminophen / diphenhydramine Oral Solution 371897 SCDF
- Acetaminophen / diphenhydramine hydrochloride Oral Solution 2648062 SCDFP
- Acetaminophen / diphenhydramine Oral Liquid Product 1151203 SCDG
- Acetaminophen / diphenhydramine Oral Product 1151204 SCDG
- Acetaminophen / diphenhydramine hydrochloride Oral Liquid Product 2660960 SCDGP
- Acetaminophen / diphenhydramine hydrochloride Oral Product 2662609 SCDGP
- Oral Solution 316968 DF
- Oral Liquid Product 1151137 DFG
- +1 more in this family
Clinical & branded drugs 2

Ingredient + strength + dose form. These are the concepts real FDA products actually carry.
- Acetaminophen 32 MG/ML 315262 SCDC
- Diphenhydramine hydrochloride 1.25 MG/ML 1049883 SCDC

Showing up to 8 concepts per family — 14 of 15 stored related concepts drawn.

These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

Acetaminophen 32 MG/ML SCDC · 315262
Diphenhydramine hydrochloride 1.25 MG/ML SCDC · 1049883
Acetaminophen / diphenhydramine Oral Solution SCDF · 371897
Acetaminophen / diphenhydramine hydrochloride Oral Solution SCDFP · 2648062
Acetaminophen / diphenhydramine Oral Liquid Product SCDG · 1151203
Acetaminophen / diphenhydramine Oral Product SCDG · 1151204
Acetaminophen / diphenhydramine hydrochloride Oral Liquid Product SCDGP · 2660960
Acetaminophen / diphenhydramine hydrochloride Oral Product SCDGP · 2662609

📦 FDA Products & Package NDCs

1 product · 2 package NDCs

2 package NDCs map to RxCUI 2683420 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.

Package NDC	Package	Brand / generic name	Labeler	Marketing start
69536-0335-04	1 BOTTLE in 1 CARTON (69536-335-04) / 118 mL in 1 BOTTLE	Dimetapp Multi-Symptom Cold and Flu	Foundation Consumer Healthcare	2024-06-01
69536-0335-08	2 BOTTLE in 1 CARTON (69536-335-08) / 118 mL in 1 BOTTLE	Dimetapp Multi-Symptom Cold and Flu	Foundation Consumer Healthcare	2025-11-01

Observed labelers: Foundation Consumer Healthcare (2) — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7

openFDA export observedJul 14, 2026

RxNorm release07/06/2026

Methodology2026-07-full-catalog-v1

A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.

This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.