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{1 (dextromethorphan hydrobromide 0.667 MG/ML / guaifenesin 13.3 MG/ML Oral Solution) / 1... — RxCUI 2685490

Name: {1 (dextromethorphan hydrobromide 0.667 MG/ML / guaifenesin 13.3 MG/ML Oral Solution)… (RxCUI 2685490)
Creator: Brian Staiger, PharmD

RxNorm drug concept · Generic pack

RxCUI 2685490 Generic pack · GPCK ● Current RxNorm concept 1 FDA product 1 package NDC Snapshot Jul 14, 2026

This page is curated, coded, and maintained by Dr. Brian Staiger, PharmD

Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI2685490

Official name{1 (dextromethorphan hydrobromide 0.667 MG/ML / guaifenesin 13.3 MG/ML Oral Solution) / 1 (diphenhydramine hydrochloride 0.833 MG/ML Oral Solution) } Pack

Concept typeGeneric pack (GPCK)

RxNorm statusCurrent RxNorm concept

Also known as1 daytime (dextromethorphan HBr 10 MG / guaifenesin 200 MG per 15 mL Oral Solution) / 1 nighttime (diphenhydramine hydrochloride 12.5 MG per 15 mL Oral Solution) Pack; 1 daytime (dextromethorphan HBr 10 MG / guaiFENesin 200 MG in 15 mL Oral Solution) / 1 nighttime (diphenhydrAMINE hydrochloride 12.5 MG in 15 mL Oral Solution) Pack

FDA products mapped1

Package NDCs mapped1

RxNorm release07/06/2026

Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Diphenhydramine Topical: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist

You can use it for temporary relief of pain and itching from everyday skin problems — things like insect bites, minor burns, minor cuts and scrapes, and general skin irritations. I...
What can I actually use this cream or spray for?
You can apply it up to 3 to 4 times a day, but no more than that. More frequent use isn't going to help more — and the label is clear that you shouldn't exceed that limit. For kids...
This is really important — do not use this topical product at the same time as any other product that contains diphenhydramine, even a pill or capsule. That includes allergy medici...

📖 Read our full Diphenhydramine Topical guide →

🕸️ Concept Web — How {1 (dextromethorphan hydrobromide 0.667 MG/ML /... Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.

This page's concept {1 (dextromethorphan hydrobromide 0.667 MG/ML / guaifenesin 13.3 MG/ML Oral Solution) / 1 (diphenhydramine hydrochloride 0.833 MG/ML Oral Solution) } Pack RxCUI 2685490 Generic pack · GPCK

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

Ingredients 6

The active substance itself — no strength, form, or brand attached yet.
- Dextromethorphan 3289 IN
- Diphenhydramine 3498 IN
- Guaifenesin 5032 IN
- Dextromethorphan / guaifenesin 214488 MIN
- Dextromethorphan hydrobromide 102490 PIN
- Diphenhydramine hydrochloride 1362 PIN
Dose forms 15

The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.
- Dextromethorphan / guaifenesin Oral Solution 371766 SCDF
- Diphenhydramine Oral Solution 371889 SCDF
- Dextromethorphan hydrobromide / guaifenesin Oral Solution 2647597 SCDFP
- Diphenhydramine hydrochloride Oral Solution 2647041 SCDFP
- Dextromethorphan / guaifenesin Oral Liquid Product 1155190 SCDG
- Dextromethorphan / guaifenesin Oral Product 1155191 SCDG
- Diphenhydramine Oral Liquid Product 1158448 SCDG
- Diphenhydramine Oral Product 1158449 SCDG
- +7 more in this family
Clinical & branded drugs 5

Ingredient + strength + dose form. These are the concepts real FDA products actually carry.
- Dextromethorphan hydrobromide 0.667 MG/ML / guaifenesin 13.3 MG/ML Oral Solution 1014005 SCD
- Diphenhydramine hydrochloride 0.833 MG/ML Oral Solution 2685488 SCD
- Dextromethorphan hydrobromide 0.667 MG/ML 1014004 SCDC
- Diphenhydramine hydrochloride 0.833 MG/ML 1294606 SCDC
- Guaifenesin 13.3 MG/ML 331390 SCDC

Showing up to 8 concepts per family — 19 of 26 stored related concepts drawn.

These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

Dextromethorphan hydrobromide 0.667 MG/ML / guaifenesin 13.3 MG/ML Oral Solution SCD · 1014005
Diphenhydramine hydrochloride 0.833 MG/ML Oral Solution SCD · 2685488
Dextromethorphan hydrobromide 0.667 MG/ML SCDC · 1014004
Diphenhydramine hydrochloride 0.833 MG/ML SCDC · 1294606
Guaifenesin 13.3 MG/ML SCDC · 331390
Dextromethorphan / guaifenesin Oral Solution SCDF · 371766
Diphenhydramine Oral Solution SCDF · 371889
Dextromethorphan hydrobromide / guaifenesin Oral Solution SCDFP · 2647597
Diphenhydramine hydrochloride Oral Solution SCDFP · 2647041
Dextromethorphan / guaifenesin Oral Liquid Product SCDG · 1155190

📦 FDA Products & Package NDCs

1 product · 1 package NDC

1 package NDC map to RxCUI 2685490 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.

Package NDC	Package	Brand / generic name	Labeler	Marketing start
84126-0312-12	1 KIT in 1 PACKAGE (84126-312-12) * 177 mL in 1 BOTTLE, PL...	Vicks DayQuil Kids and Vicks NyQuil Kids FREE OF ARTIFICIAL DYES and SUGAR COLD and COUGH plus	The Procter & Gamble Manufacturing Company	2024-06-25

Observed labelers: The Procter & Gamble Manufacturing Company (1) — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7

openFDA export observedJul 14, 2026

RxNorm release07/06/2026

Methodology2026-07-full-catalog-v1

A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.

This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.