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Acetaminophen 43.3 MG/ML / dextromethorphan hydrobromide 1.33 MG/ML / doxylamine succinate... — RxCUI 2733907

Name: Acetaminophen 43.3 MG/ML / dextromethorphan hydrobromide 1.33 MG/ML / doxylamine succ… (RxCUI 2733907)
Creator: Brian Staiger, PharmD

RxNorm drug concept · Semantic clinical drug

RxCUI 2733907 Semantic clinical drug · SCD ● Current RxNorm concept 1 FDA product 1 package NDC Snapshot Jul 14, 2026

This page is curated, coded, and maintained by Dr. Brian Staiger, PharmD

Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI2733907

Official nameAcetaminophen 43.3 MG/ML / dextromethorphan hydrobromide 1.33 MG/ML / doxylamine succinate 0.833 MG/ML / phenylephrine hydrochloride 0.667 MG/ML Oral Solution

Concept typeSemantic clinical drug (SCD)

RxNorm statusCurrent RxNorm concept

Also known asacetaminophen 650 MG / dextromethorphan HBr 20 MG / doxylamine succinate 12.5 MG / phenylephrine hydrochloride 10 MG per 15 ML Oral Solution; acetaminophen 650 MG / dextromethorphan HBr 20 MG / doxylamine succinate 12.5 MG / phenylephrine HCl 10 MG in 15 mL Oral Solution; APAP 43.3 MG/ML / dextromethorphan hydrobromide 1.33 MG/ML / doxylamine succinate 0.833 MG/ML / phenylephrine hydrochloride 0.667 MG/ML Oral Solution

FDA products mapped1

Package NDCs mapped1

RxNorm release07/06/2026

Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Phenylephrine: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist

Yes, it's the same active ingredient, but used in very different ways depending on the form. The nasal spray delivers a tiny amount directly to the nasal lining to temporarily shri...
I see phenylephrine in nasal sprays at the pharmacy AND as an IV drug in the hospital — is it really the same medication?
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Can I use the nasal spray if I have high blood pressure or heart disease?

📖 Read our full Phenylephrine guide →

🕸️ Concept Web — How Acetaminophen 43.3 MG/ML / dextromethorphan hydr... Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.

This page's concept Acetaminophen 43.3 MG/ML / dextromethorphan hydrobromide 1.33 MG/ML / doxylamine succinate 0.833 MG/ML / phenylephrine hydrochloride 0.667 MG/ML Oral Solution RxCUI 2733907 Semantic clinical drug · SCD

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

Ingredients 8

The active substance itself — no strength, form, or brand attached yet.
- Acetaminophen 161 IN
- Dextromethorphan 3289 IN
- Doxylamine 3642 IN
- Phenylephrine 8163 IN
- Acetaminophen / dextromethorphan / doxylamine / phenylephrine 1008701 MIN
- Dextromethorphan hydrobromide 102490 PIN
- Doxylamine succinate 23665 PIN
- Phenylephrine hydrochloride 8164 PIN
Dose forms 9

The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.
- Acetaminophen / dextromethorphan / doxylamine / phenylephrine Oral Solution 647202 SCDF
- Acetaminophen / dextromethorphan hydrobromide / doxylamine succinate / phenylephrine hydrochloride Oral Solution 2649073 SCDFP
- Acetaminophen / dextromethorphan / doxylamine / phenylephrine Oral Liquid Product 1155607 SCDG
- Acetaminophen / dextromethorphan / doxylamine / phenylephrine Oral Product 1155896 SCDG
- Acetaminophen / dextromethorphan hydrobromide / doxylamine succinate / phenylephrine hydrochloride Oral Liquid Product 2663084 SCDGP
- Acetaminophen / dextromethorphan hydrobromide / doxylamine succinate / phenylephrine hydrochloride Oral Product 2660518 SCDGP
- Oral Solution 316968 DF
- Oral Liquid Product 1151137 DFG
- +1 more in this family
Clinical & branded drugs 4

Ingredient + strength + dose form. These are the concepts real FDA products actually carry.
- Acetaminophen 43.3 MG/ML 332345 SCDC
- Dextromethorphan hydrobromide 1.33 MG/ML 1246337 SCDC
- Doxylamine succinate 0.833 MG/ML 2733906 SCDC
- Phenylephrine hydrochloride 0.667 MG/ML 1303844 SCDC

Showing up to 8 concepts per family — 20 of 21 stored related concepts drawn.

These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

Acetaminophen 43.3 MG/ML SCDC · 332345
Dextromethorphan hydrobromide 1.33 MG/ML SCDC · 1246337
Doxylamine succinate 0.833 MG/ML SCDC · 2733906
Phenylephrine hydrochloride 0.667 MG/ML SCDC · 1303844
Acetaminophen / dextromethorphan / doxylamine / phenylephrine Oral Solution SCDF · 647202
Acetaminophen / dextromethorphan hydrobromide / doxylamine succinate / phenylephrine hydrochloride Oral Solution SCDFP · 2649073
Acetaminophen / dextromethorphan / doxylamine / phenylephrine Oral Liquid Product SCDG · 1155607
Acetaminophen / dextromethorphan / doxylamine / phenylephrine Oral Product SCDG · 1155896
Acetaminophen / dextromethorphan hydrobromide / doxylamine succinate / phenylephrine hydrochloride Oral Liquid Product SCDGP · 2663084
Acetaminophen / dextromethorphan hydrobromide / doxylamine succinate / phenylephrine hydrochloride Oral Product SCDGP · 2660518

📦 FDA Products & Package NDCs

1 product · 1 package NDC

1 package NDC map to RxCUI 2733907 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.

Package NDC	Package	Brand / generic name	Labeler	Marketing start
87078-0872-32	12 POUCH in 1 CARTON (87078-872-32) / 15 mL in 1 POUCH (870...	ONESSIP ADULT NIGHTTIME SEVERE COLD AND FLU	MEDWISE LIFESCIENCES INC.	2026-01-28

Observed labelers: MEDWISE LIFESCIENCES INC. (1) — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7

openFDA export observedJul 14, 2026

RxNorm release07/06/2026

Methodology2026-07-full-catalog-v1

A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.

This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.