Phenylephrine

Generic name: Pronounced as (fen il ef' rin)
Brand names
  • Children's Sudafed PE Nasal Decongestant®
  • Lusonal®
  • PediaCare Children's Decongestant®
  • Sudafed PE Congestion®
  • Suphedrin PE®
Click on drug name to hear pronunciation

Medical Content Reviewed By HelloPharmacist Staff

Last Revised - 08/15/2018

Phenylephrine is used to relieve nasal discomfort caused by colds, allergies, and hay fever. It is also used to relieve sinus congestion and pressure. Phenylephrine will relieve symptoms but will not treat the cause of the symptoms or speed recovery. Phenylephrine is in a class of medications called nasal decongestants. It works by reducing swelling of the blood vessels in the nasal passages.

Phenylephrine comes as a tablet, a liquid, or a dissolving strip to take by mouth. It is usually taken every 4 hours as needed. Follow the directions on your prescription label or the package label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take phenylephrine exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor or directed on the label.

Phenylephrine comes alone and in combination with other medications. Ask your doctor or pharmacist for advice on which product is best for your symptoms. Check nonprescription cough and cold product labels carefully before using two or more products at the same time. These products may contain the same active ingredient(s) and taking them together could cause you to receive an overdose. This is especially important if you will be giving cough and cold medications to a child.

Nonprescription cough and cold combination products, including products that contain phenylephrine, can cause serious side effects or death in young children. Do not give these products to children younger than 4 years of age. If you give these products to children 4 to 11 years of age, use caution and follow the package directions carefully.

If you are giving phenylephrine or a combination product that contains phenylephrine to a child, read the package label carefully to be sure that it is the right product for a child of that age. Do not give phenylephrine products that are made for adults to children.

Before you give a phenylephrine product to a child, check the package label to find out how much medication the child should receive. Give the dose that matches the child's age on the chart. Ask the child's doctor if you don't know how much medication to give the child.

If you are taking the liquid, do not use a household spoon to measure your dose. Use the measuring spoon or cup that came with the medication or use a spoon made especially for measuring medication.

If your symptoms do not get better within 7 days or if you have a fever, stop taking phenylephrine and call your doctor.

If you are taking the dissolving strips, place one strip on your tongue and allow it to dissolve.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Before taking phenylephrine,

  • tell your doctor and pharmacist if you are allergic to phenylephrine, any other medications, or any of the ingredients in phenylephrine preparations.

  • do not take phenylephrine if you are taking a monoamine oxidase (MAO) inhibitor, such as isocarboxazid (Marplan), phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), and tranylcypromine (Parnate), or if you have stopped taking one of these medications within the past 2 weeks.

  • tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take.

  • tell your doctor if you have or have ever had high blood pressure, diabetes, trouble urinating because of an enlarged prostate gland, or thyroid or heart disease.

  • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking phenylephrine, call your doctor.

  • if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking phenylephrine.

  • if you have phenylketonuria (PKU, an inherited condition in which a special diet must be followed to prevent mental retardation), you should know that some phenylephrine products may be sweetened with aspartame, a source of phenylalanine.

Unless your doctor tells you otherwise, continue your normal diet.

This medication is usually taken as needed. If your doctor has told you to take phenylephrine regularly, take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

  • Phenylephrine may cause side effects. Some side effects can be serious. If you experience any of these symptoms, stop using phenylephrine and call your doctor:

    • nervousness

    • dizziness

    • sleeplessness

  • Phenylephrine may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

  • If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Ask your pharmacist any questions you have about phenylephrine.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

  • A Tan 12x Suspension® (containing Phenylephrine, Pyrilamine)
  • AccuHist PDX® (containing Brompheniramine, Dextromethorphan, Phenylephrine)
  • AccuHist® (containing Chlorpheniramine, Phenylephrine)
  • Actifed Cold and Allergy® (containing Chlorpheniramine, Phenylephrine)
  • Advil Congestion Relief® (containing Ibuprofen, Phenylephrine)
  • Aerohist Plus® (containing Chlorpheniramine, Methscopolamine, Phenylephrine)
  • Aerokid® (containing Chlorpheniramine, Methscopolamine, Phenylephrine)
  • Ah Chew Ultra® (containing Chlorpheniramine, Phenylephrine, Methscopolamine)
  • Ah Chew® (containing Chlorpheniramine, Phenylephrine)
  • Alahist DM® (containing Brompheniramine, Dextromethorphan, Phenylephrine)
  • Alahist LQ® (containing Diphenhydramine, Phenylephrine)
  • Albatussin NN® (containing Dextromethorphan, Phenylephrine, Potassium Guaiacolsulfonate, Pyrilamine)
  • Aldex CT® (containing Diphenhydramine, Phenylephrine)
  • Aldex D® (containing Phenylephrine, Pyrilamine)
  • Alka-Seltzer Plus Cold and Cough Formula® (containing Aspirin, Chlorpheniramine, Dextromethorphan, Phenylephrine)
  • Alka-Seltzer Plus Day and Night Cold Formulas® (containing Aspirin, Dextromethorphan, Phenylephrine)
  • Alka-Seltzer Plus Day Non-Drowsy Cold Formula® (containing Acetaminophen, Dextromethorphan, Phenylephrine)
  • Alka-Seltzer Plus Fast Powder Packs® (containing Acetaminophen, Chlorpheniramine, Phenylephrine)
  • Alka-Seltzer Plus Flu Formula® (containing Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylephrine)
  • Alka-Seltzer Plus Night Cold Formula® (containing Aspirin, Dextromethorphan, Doxylamine, Phenylephrine)
  • Alka-Seltzer Plus Sinus Formula® (containing Aspirin, Phenylephrine)
  • Alka-Seltzer Plus Sparkling Original Cold Formula® (containing Aspirin, Chlorpheniramine, Phenylephrine)
  • Allerest PE® (containing Chlorpheniramine, Phenylephrine)
  • Allergy DN PE® (containing Chlorpheniramine, Methscopolamine, Phenylephrine)
  • AlleRx® (containing Chlorpheniramine, Phenylephrine)
  • Amerituss AD® (containing Chlorpheniramine, Dextromethorphan, Phenylephrine)
  • Aquatab C® (containing Carbetapentane, Dextromethorphan, Guaifenesin, Phenylephrine)
  • Aridex® (containing Carbetapentane, Carbinoxamine, Phenylephrine)
  • B Vex D® (containing Brompheniramine, Phenylephrine)
  • Balacall DM® (containing Brompheniramine, Dextromethorphan, Phenylephrine)
  • Baltussin HC® (containing Chlorpheniramine, Hydrocodone, Phenylephrine)
  • Benadryl-D Allergy Plus Sinus® (containing Diphenhydramine, Phenylephrine)
  • Betatan® (containing Brompheniramine, Carbetapentane, Phenylephrine)
  • Biotuss® (containing Dextromethorphan, Guaifenesin, Phenylephrine)
  • BPM PE DM® (containing Brompheniramine, Dextromethorphan, Phenylephrine)
  • Bromaphedrine D® (containing Brompheniramine, Phenylephrine)
  • Bromhist PDX® (containing Brompheniramine, Dextromethorphan, Guaifenesin, Phenylephrine)
  • Bromtuss DM® (containing Brompheniramine, Dextromethorphan, Phenylephrine)
  • Broncopectol® (containing Chlorpheniramine, Dextromethorphan, Guaifenesin, Phenylephrine)
  • Bronkids® (containing Chlorpheniramine, Dextromethorphan, Phenylephrine)
  • Brontuss DX® (containing Dextromethorphan, Guaifenesin, Phenylephrine)
  • Brontuss SF® (containing Dextromethorphan, Guaifenesin, Phenylephrine)
  • Brotapp PE-DM Cough and Cold® (containing Brompheniramine, Dextromethorphan, Phenylephrine)
  • Brovex D® (containing Brompheniramine, Phenylephrine)
  • Brovex PEB DM® (containing Brompheniramine, Dextromethorphan, Phenylephrine)
  • Brovex PEB® (containing Brompheniramine, Phenylephrine)
  • C Phen DM® (containing Chlorpheniramine, Dextromethorphan, Phenylephrine)
  • C Phen® (containing Chlorpheniramine, Phenylephrine)
  • Cardec DM® (containing Chlorpheniramine, Dextromethorphan, Phenylephrine)
  • Centergy DM® (containing Chlorpheniramine, Dextromethorphan, Phenylephrine)
  • Centergy® (containing Chlorpheniramine, Phenylephrine)
  • Centussin DHC® (containing Brompheniramine, Dihydrocodeine, Phenylephrine)
  • Ceron DM® (containing Chlorpheniramine, Dextromethorphan, Phenylephrine)
  • Ceron® (containing Chlorpheniramine, Phenylephrine)
  • Cerose DM® (containing Chlorpheniramine, Dextromethorphan, Phenylephrine)
  • Children's Dimetapp Cold and Allergy® (containing Brompheniramine, Phenylephrine)
  • Children's Dimetapp Cold and Cough® (containing Brompheniramine, Dextromethorphan, Phenylephrine)
  • Children's Dimetapp Multisymptom Cold and Flu® (containing Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylephrine)
  • Children's Dimetapp Nighttime Cold and Congestion® (containing Diphenhydramine, Phenylephrine)
  • Children's Mucinex Multi-Symptom Cold® (containing Dextromethorphan, Guaifenesin, Phenylephrine)
  • Children's Mucinex Stuffy Nose and Cold® (containing Guaifenesin, Phenylephrine)
  • Children's Robitussin Cough and Cold CF® (containing Dextromethorphan, Guaifenesin, Phenylephrine)
  • Children's Sudafed PE Cold and Cough® (containing Dextromethorphan, Phenylephrine)
  • Chlordex GP® (containing Chlorpheniramine, Dextromethorphan, Guaifenesin, Phenylephrine)
  • Codal-DM® (containing Dextromethorphan, Phenylephrine, Pyrilamine)
  • Codimal DM® (containing Dextromethorphan, Phenylephrine, Pyrilamine)
  • Comtrex Cold and Cough Day/Night® (containing Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylephrine)
  • Comtrex Cold and Cough Non-Drowsy® (containing Acetaminophen, Dextromethorphan, Phenylephrine)
  • Contac Cold and Flu® (containing Acetaminophen, Phenylephrine)
  • Corfen DM® (containing Chlorpheniramine, Dextromethorphan, Phenylephrine)
  • Coryza DM® (containing Dexchlorpheniramine, Dextromethorphan, Phenylephrine, Pyrilamine)
  • Dallergy Drops® (containing Chlorpheniramine, Phenylephrine)
  • Dallergy PE® (containing Chlorpheniramine, Methscopolamine, Phenylephrine)
  • Decon E® (containing Guaifenesin, Phenylephrine)
  • Decon G® (containing Brompheniramine, Guaifenesin, Phenylephrine)
  • Deconex® (containing Guaifenesin, Phenylephrine)
  • Dehistine® (containing Chlorpheniramine, Methscopolamine, Phenylephrine)
  • Despec NR® (containing Dextromethorphan, Guaifenesin, Phenylephrine)
  • Despec® (containing Guaifenesin, Phenylephrine)
  • Donatuss DC® (containing Dihydrocodeine, Guaifenesin, Phenylephrine)
  • Donatussin DM® (containing Chlorpheniramine, Dextromethorphan, Phenylephrine)
  • Donatussin MAX® (containing Carbinoxamine, Hydrocodone, Phenylephrine)
  • Donatussin® (containing Guaifenesin, Phenylephrine)
  • Dristan Cold Multi-Symptom Formula® (containing Acetaminophen, Chlorpheniramine, Phenylephrine)
  • Dryphen® (containing Acetaminophen, Chlorpheniramine, Phenylephrine)
  • Duravent-DPB® (containing Brompheniramine, Dextromethorphan, Phenylephrine)
  • Dynatuss EX® (containing Dextromethorphan, Guaifenesin, Phenylephrine)
  • EndaCof-DH® (containing Brompheniramine, Dihydrocodeine, Phenylephrine)
  • EndaCof-Plus® (containing Dexchlorpheniramine, Hydrocodone, Phenylephrine)
  • Endacon DM® (containing Dextromethorphan, Guaifenesin, Phenylephrine)
  • Endal CD® (containing Chlorpheniramine, Codeine, Phenylephrine)
  • Endal HD® (containing Diphenhydramine, Phenylephrine)
  • Entex LA® (containing Guaifenesin, Phenylephrine)
  • Entex LQ® (containing Guaifenesin, Phenylephrine)
  • Excedrin Sinus Headache® (containing Acetaminophen, Phenylephrine)
  • Execof® (containing Dextromethorphan, Guaifenesin, Phenylephrine)
  • Extendryl® (containing Chlorpheniramine, Methscopolamine, Phenylephrine)
  • Genetuss 2® (containing Dextromethorphan, Guaifenesin, Phenylephrine)
  • Gentex LQ® (containing Carbetapentane, Guaifenesin, Phenylephrine)
  • Giltuss® (containing Dextromethorphan, Guaifenesin, Phenylephrine)
  • Guiatex PE® (containing Guaifenesin, Phenylephrine)
  • Histadec® (containing Chlorpheniramine, Phenylephrine)
  • Histinex HC® (containing Chlorpheniramine, Hydrocodone, Phenylephrine)
  • Hycomine Compound® (containing Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine)
  • J-Max® (containing Guaifenesin, Phenylephrine)
  • J-Tan D PD® (containing Brompheniramine, Phenylephrine)
  • Lartus® (containing Dextromethorphan, Guaifenesin, Phelyephrine)
  • Levall® (containing Carbetapentane, Guaifenesin, Phenylephrine)
  • Liquibid D-R® (containing Guaifenesin, Phenylephrine)
  • Liquibid PD-R® (containing Guaifenesin, Phenylephrine)
  • Lohist-DM® (containing Brompheniramine, Dextromethorphan, Phenylephrine)
  • LoHist-PEB-DM® (containing Brompheniramine, Dextromethorphan, Phenylephrine)
  • LoHist-PEB® (containing Brompheniramine, Phenylephrine)
  • Lortuss HC® (containing Hydrocodone, Phenylephrine)
  • Lusair® (containing Guaifenesin, Phenylephrine)
  • Lusonex® (containing Guaifenesin, Phenylephrine)
  • Maxiphen ADT® (containing Chlorpheniramine, Dextromethorphan, Phenylephrine)
  • Maxiphen® (containing Guaifenesin, Phenylephrine)
  • Mintuss DR® (containing Chlorpheniramine, Dextromethorphan, Phenylephrine)
  • Montephen® (containing Guaifenesin, Phenylephrine)
  • MyHist DM® (containing Dextromethorphan, Phenylephrine, Pyrilamine)
  • Naldex® (containing Dexchlorpheniramine, Phenylephrine)
  • Nariz® (containing Guaifenesin, Phenylephrine)
  • Nasohist DM® (containing Chlorpheniramine, Dextromethorphan, Phenylephrine)
  • Nasohist® (containing Chlorpheniramine, Phenylephrine)
  • Neo DM® (containing Chlorpheniramine, Dextromethorphan, Phenylephrine)
  • NoHist-DM® (containing Chlorpheniramine, Dextromethorphan, Phenylephrine)
  • NoHist-LQ® (containing Chlorpheniramine, Phenylephrine)
  • NoHist® (containing Chlorpheniramine, Phenylephrine)
  • Norel DM® (containing Chlorpheniramine, Dextromethorphan, Phenylephrine)
  • Norel SR® (containing Acetaminophen, Chlorpheniramine, Phenylephrine, Phenyltoloxamine)
  • Notuss-PE® (containing Codeine, Phenylephrine)
  • Novahistine® (containing Chlorpheniramine, Phenylephrine)
  • Omnihist II LA® (containing Chlorpheniramine, Methscopolamine, Phenylephrine)
  • Oratuss® (containing Carbetapentane, Guaifenesin, Phenylephrine)
  • PediaCare Children's Allergy and Cold® (containing Diphenhydramine, Phenylephrine)
  • PediaCare Children's Fever Reducer Plus Flu® (containing Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylephrine)
  • PediaCare Children's Fever Reducer Plus Multi-Symptom Cold® (containing Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylephrine)
  • PediaCare Children's Multi-Symptom Cold® (containing Dextromethorphan, Phenylephrine)
  • Phenabid® (containing Chlorpheniramine, Phenylephrine)
  • Phencarb GG® (containing Carbetapentane, Guaifenesin, Phenylephrine)
  • Phenergan VC® (containing Phenylephrine, Promethazine)
  • Poly Hist DHC® (containing Dihydrocodeine, Phenylephrine, Pyrilamine)
  • Poly Hist DM® (containing Dextromethorphan, Phenylephrine, Pyrilamine)
  • Poly Hist PD® (containing Chlorpheniramine, Phenylephrine, Pyrilamine)
  • Poly-Tussin AC® (containing Brompheniramine, Codeine, Phenylephrine)
  • Poly-Tussin DM® (containing Chlorpheniramine, Dextromethorphan, Phenylephrine)
  • Poly-Tussin EX® (containing Dihydrocodeine, Guaifenesin, Phenylephrine)
  • Polytan D® (containing Dexbrompheniramine, Phenylephrine)
  • Polytan DM® (containing Dexbrompheniramine, Dextromethorphan, Phenylephrine, Pyrilamine)
  • Prolex PD® (containing Guaifenesin, Phenylephrine)
  • Prometh VC® (containing Phenylephrine, Promethazine)
  • Promethazine VC® (containing Phenylephrine, Promethazine)
  • Protid® (containing Acetaminophen, Chlorpheniramine, Phenylephrine)
  • Pyrlex PD® (containing Phenylephrine, Pyrilamine)
  • Quartuss DM® (containing Chlorpheniramine, Dextromethorphan, Phenylephrine)
  • Quartuss® (containing Chlorpheniramine, Dextromethorphan, Guaifenesin, Phenylephrine)
  • Quintex® (containing Guaifenesin, Phenylephrine)
  • R-Tanna® (containing Chlorpheniramine, Phenylephrine)
  • Re Allergy AM/PM® (containing Chlorpheniramine, Methscopolamine, Phenylephrine)
  • Re Drylex® (containing Dexchlorpheniramine, Methscopolamine, Phenylephrine)
  • Redur PCM® (containing Chlorpheniramine, Phenylephrine)
  • Relcof PE® (containing Chlorpheniramine, Methscopolamine, Phenylephrine)
  • RemeHist DM® (containing Dextromethorphan, Phenylephrine, Pyrilamine)
  • RemeTussin DM® (containing Chlorpheniramine, Dextromethorphan, Phenylephrine)
  • Rescon® (containing Chlorpheniramine, Methscopolamine, Phenylephrine)
  • Respa PE® (containing Guaifenesin, Phenylephrine)
  • RespaHist II® (containing Brompheniramine, Phenylephrine)
  • Resperal® (containing Dexchlorpheniramine, Dextromethorphan, Phenylephrine, Pyrilamine)
  • Rhinabid® (containing Brompheniramine, Phenylephrine)
  • RhinaHist® (containing Dexchlorpheniramine, Phenylephrine)
  • Rinate® (containing Chlorpheniramine, Phenylephrine)
  • Robitussin Cough and Cold CF® (containing Dextromethorphan, Guaifenesin, Phenylephrine)
  • Robitussin Night Time Cough and Cold® (containing Diphenhydramine, Phenylephrine)
  • Robitussin Night Time Cough, Cold, and Flu® (containing Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylephrine)
  • Rondex® (containing Chlorpheniramine, Phenylephrine)
  • Ry-Tuss® (containing Carbetapentane, Chlorpheniramine, Ephedrine, Phenylephrine)
  • Ryna® (containing Phenylephrine, Pyrilamine)
  • Rynatan® (containing Chlorpheniramine, Phenylephrine)
  • Rynatuss® (containing Carbetapentane, Chlorpheniramine, Ephedrine, Phenylephrine)
  • ScopoHist® (containing Chlorpheniramine, Methscopolamine, Phenylephrine)
  • Seradex® (containing Brompheniramine, Phenylephrine)
  • Sildec PE DM® (containing Chlorpheniramine, Dextromethorphan, Phenylephrine)
  • Sine-Off Cough/Cold® (containing Acetaminophen, Dextromethorphan, Guaifenesin, Phenylephrine)
  • Sine-Off Non-Drowsy® (containing Acetaminophen, Phenylephrine)
  • Sine-Off Severe Cold® (containing Acetaminophen, Guaifenesin, Phenylephrine)
  • Sine-Off Sinus/Cold® (containing Acetaminophen, Chlorpheniramine, Phenylephrine)
  • Sinutuss DM® (containing Dextromethorphan, Guaifenesin, Phenylephrine)
  • Sinuvent PE® (containing Guaifenesin, Phenylephrine)
  • Sitrex® (containing Guaifenesin, Phenylephrine)
  • Sonahist DM® (containing Chlorpheniramine, Dextromethorphan, Phenylephrine)
  • Sonahist® (containing Chlorpheniramine, Phenylephrine)
  • Statuss DM® (containing Chlorpheniramine, Dextromethorphan, Phenylephrine)
  • Sudafed PE Cold/Cough® (containing Acetaminophen, Dextromethorphan, Guaifenesin, Phenylephrine)
  • Sudafed PE Day/Night Cold® (containing Acetaminophen, Dextromethorphan, Diphenhydramine, Guaifenesin, Phenylephrine)
  • Sudafed PE Day/Night Congestion® (containing Diphenhydramine, Phenylephrine)
  • Sudafed PE Non-Drying Sinus® (containing Guaifenesin, Phenylephrine)
  • Sudafed PE Pressure/Pain® (containing Acetaminophen, Phenylephrine)
  • Sudafed PE Severe Cold® (containing Acetaminophen, Diphenhydramine, Phenylephrine)
  • Sudafed PE Sinus/Allergy® (containing Chlorpheniramine, Phenylephrine)
  • Sudafed PE Triple Action® (containing Acetaminophen, Guaifenesin, Phenylephrine)
  • Sympak PDX® (containing Chlorpheniramine, Methscopolamine, Phenylephrine)
  • Tanabid® (containing Brompheniramine, Phenylephrine)
  • Tannate® (containing Carbetapentane, Phenylephrine, Pyrilamine)
  • Theraflu Cold and Cough® (containing Dextromethorphan, Pheniramine, Phenylephrine)
  • Theraflu Cold and Sore Throat® (containing Acetaminophen, Pheniramine, Phenylephrine)
  • Theraflu Daytime Severe Cold and Cough® (containing Acetaminophen, Dextromethorphan, Phenylephrine)
  • Theraflu Flu and Sore Throat® (containing Acetaminophen, Pheniramine, Phenylephrine)
  • Theraflu Nighttime Severe Cold and Cough® (containing Acetaminophen, Diphenhydramine, Phenylephrine)
  • Theraflu Sinus and Cold® (containing Acetaminophen, Pheniramine, Phenylephrine)
  • Trexbrom® (containing Brompheniramine, Carbetapentane, Phenylephrine)
  • Triall® (containing Chlorpheniramine, Methscopolamine, Phenylephrine)
  • Triaminic Chest and Nasal Congestion® (containing Guaifenesin, Phenylephrine)
  • Triaminic Cold and Allergy® (containing Chlorpheniramine, Phenylephrine)
  • Triaminic Day Time Cold and Cough® (containing Dextromethorphan, Phenylephrine)
  • Triaminic Night Time Cold and Cough® (containing Diphenhydramine, Phenylephrine)
  • Triplex DM® (containing Dextromethorphan, Phenylephrine, Pyrilamine)
  • Trital DM® (containing Chlorpheniramine, Dextromethorphan, Phenylephrine)
  • Tritan® (containing Chlorpheniramine, Phenylephrine, Pyrilamine)
  • Trituss® (containing Dextromethorphan, Guaifenesin, Phenylephrine)
  • Tusdec DM® (containing Brompheniramine, Dextromethorphan, Phenylephrine)
  • Tussafed EX® (containing Dextromethorphan, Guaifenesin, Phenylephrine)
  • Tussbid® (containing Guaifenesin, Phenylephrine)
  • Tussi 12D® (containing Carbetapentane, Phenylephrine, Pyrilamine)
  • Tussi Pres® (containing Dextromethorphan, Guaifenesin, Phenylephrine)
  • Tussidex® (containing Dextromethorphan, Guaifenesin, Phenylephrine)
  • Tussin CF® (containing Dextromethorphan, Guaifenesin, Phenylephrine)
  • Tylenol Allergy Multi-Symptom Nighttime® (containing Acetaminophen, Diphenhydramine, Phenylephrine)
  • Tylenol Allergy Multi-Symptom® (containing Acetaminophen, Chlorpheniramine, Phenylephrine)
  • Tylenol Cold and Flu Severe® (containing Acetaminophen, Dextromethorphan, Guaifenesin, Phenylephrine)
  • Tylenol Cold Multi-Symptom Nighttime® (containing Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylephrine)
  • Tylenol Cold Multi-Symptom Severe® (containing Acetaminophen, Dextromethorphan, Guaifenesin, Phenylephrine)
  • Tylenol Sinus Congestion and Pain Daytime® (containing Acetaminophen, Phenylephrine)
  • Tylenol Sinus Congestion and Pain Nighttime® (containing Acetaminophen, Chlorpheniramine, Phenylephrine)
  • Tylenol Sinus Congestion and Pain Severe® (containing Acetaminophen, Guaifenesin, Phenylephrine)
  • V Tann® (containing Phenylephrine, Pyrilamine)
  • V-Cof® (containing Brompheniramine, Carbetapentane, Phenylephrine)
  • V-Hist® (containing Brompheniramine, Phenylephrine)
  • Vanacof CD® (containing Dexchlorpheniramine, Phenylephrine)
  • Vazobid® (containing Brompheniramine, Phenylephrine)
  • Vazotan® (containing Brompheniramine, Carbetapentane, Phenylephrine)
  • Vicks DayQuil Cold and Flu Relief® (containing Acetaminophen, Dextromethorphan, Phenylephrine)
  • Vicks DayQuil Cold and Flu Symptom Relief Plus Vitamin C® (containing Acetaminophen, Dextromethorphan, Phenylephrine)
  • Vicks DayQuil Sinex Daytime Sinus Relief® (containing Acetaminophen, Phenylephrine)
  • Vicks Formula 44 Custom Care Congestion® (containing Dextromethorphan, Phenylephrine)
  • Vicks NyQuil Sinex Nighttime Sinus Relief® (containing Acetaminophen, Doxylamine, Phenylephrine)
  • Vicks VapoSyrup Severe Congestion® (containing Guaifenesin, Phenylephrine)
  • Viratan DM® (containing Dextromethorphan, Phenylephrine, Pyrilamine)
  • Viravan DM® (containing Dextromethorphan, Phenylephrine, Pyrilamine)
  • Viravan T® (containing Phenylephrine, Pyrilamine)
  • Visonex® (containing Guaifenesin, Phenylephrine)
  • Wellbid D® (containing Guaifenesin, Phenylephrine)
  • Y-Cof DMX® (containing Brompheniramine, Dextromethorphan, Phenylephrine)
  • Z-Dex® (containing Dextromethorphan, Guaifenesin, Phenylephrine)
  • Zotex® (containing Dextromethorphan, Guaifenesin, Phenylephrine)

Drug Interaction
Leflunomide Leflunomide The metabolism of Leflunomide can be increased when combined with Phenylephrine.
Aminophylline Aminophylline The metabolism of Aminophylline can be increased when combined with Phenylephrine.
Anagrelide Anagrelide The metabolism of Anagrelide can be increased when combined with Phenylephrine.
Candesartan Candesartan Phenylephrine may decrease the antihypertensive activities of Candesartan.
Cilostazol Cilostazol The metabolism of Cilostazol can be increased when combined with Phenylephrine.
Clopidogrel Clopidogrel The metabolism of Clopidogrel can be increased when combined with Phenylephrine.
Estrogen and Progestin (Oral Contraceptives) Estrogen and Progestin (Oral Contraceptives) The metabolism of Conjugated estrogens can be increased when combined with Phenylephrine.
Guanfacine Guanfacine The risk or severity of hypertension can be increased when Phenylephrine is combined with Guanfacine.
Methylergonovine Methylergonovine Methylergometrine may increase the hypertensive and vasoconstricting activities of Phenylephrine.
Naratriptan Naratriptan The risk or severity of hypertension can be increased when Phenylephrine is combined with Naratriptan.
Olsalazine Olsalazine The risk or severity of hypertension can be increased when Phenylephrine is combined with Olsalazine.
Penbutolol Penbutolol The therapeutic efficacy of Phenylephrine can be decreased when used in combination with Acebutolol.
Prednisone Prednisone The risk or severity of hypertension can be increased when Prednisone is combined with Phenylephrine.
Ranitidine Ranitidine The metabolism of Ranitidine can be increased when combined with Phenylephrine.
Reserpine Reserpine Phenylephrine may decrease the antihypertensive activities of Reserpine.
Rizatriptan Rizatriptan The risk or severity of hypertension can be increased when Phenylephrine is combined with Rizatriptan.
Sumatriptan Sumatriptan The risk or severity of hypertension can be increased when Phenylephrine is combined with Sumatriptan.
Tizanidine Tizanidine The metabolism of Tizanidine can be increased when combined with Phenylephrine.
Triamcinolone Triamcinolone The risk or severity of hypertension can be increased when Triamcinolone is combined with Phenylephrine.
Zolmitriptan Zolmitriptan The metabolism of Zolmitriptan can be increased when combined with Phenylephrine.
Methylprednisolone Injection Methylprednisolone Injection The risk or severity of hypertension can be increased when Methylprednisolone is combined with Phenylephrine.
Metoclopramide Injection Metoclopramide Injection The metabolism of Metoclopramide can be increased when combined with Phenylephrine.
Altretamine Altretamine Amphetamine may increase the hypertensive activities of Phenylephrine.
Cyclosporine Cyclosporine The risk or severity of hypertension can be increased when Cyclosporine is combined with Phenylephrine.
Torsemide Torsemide Phenylephrine may decrease the antihypertensive activities of Torasemide.
Olanzapine Olanzapine The therapeutic efficacy of Phenylephrine can be decreased when used in combination with Olanzapine.
Alosetron Alosetron The metabolism of Alosetron can be increased when combined with Phenylephrine.
Eprosartan Eprosartan Phenylephrine may decrease the antihypertensive activities of Eprosartan.
Meloxicam Meloxicam The risk or severity of hypertension can be increased when Phenylephrine is combined with Meloxicam.
Telmisartan Telmisartan Phenylephrine may decrease the antihypertensive activities of Telmisartan.
Linezolid Linezolid The risk or severity of hypertension can be increased when Linezolid is combined with Phenylephrine.
Trimipramine Trimipramine Trimipramine may increase the vasopressor activities of Phenylephrine.
Glycopyrrolate Glycopyrrolate The risk or severity of Tachycardia can be increased when Phenylephrine is combined with Glycopyrronium.
Perindopril Perindopril Phenylephrine may decrease the antihypertensive activities of Perindopril.
Choline Magnesium Trisalicylate Choline Magnesium Trisalicylate The risk or severity of hypertension can be increased when Phenylephrine is combined with Choline magnesium trisalicylate.
Dutasteride Dutasteride The risk or severity of hypertension can be increased when Phenylephrine is combined with Dutasteride.
Epinephrine Injection Epinephrine Injection The therapeutic efficacy of Phenylephrine can be increased when used in combination with Epinephrine.
Eplerenone Eplerenone Phenylephrine may decrease the antihypertensive activities of Eplerenone.
Olmesartan Olmesartan Phenylephrine may decrease the antihypertensive activities of Olmesartan.
Zonisamide Zonisamide The risk or severity of hypertension can be decreased when Zonisamide is combined with Phenylephrine.
Aripiprazole Aripiprazole The therapeutic efficacy of Phenylephrine can be decreased when used in combination with Aripiprazole.
Atomoxetine Atomoxetine The risk or severity of hypertension can be increased when Atomoxetine is combined with Phenylephrine.
Dexmethylphenidate Dexmethylphenidate The risk or severity of hypertension can be increased when Phenylephrine is combined with Dexmethylphenidate.
Teriparatide Injection Teriparatide Injection The risk or severity of adverse effects can be increased when Phenylephrine is combined with Teriparatide.
Almotriptan Almotriptan The risk or severity of hypertension can be increased when Phenylephrine is combined with Almotriptan.
Eletriptan Eletriptan The risk or severity of hypertension can be increased when Eletriptan is combined with Phenylephrine.
Vardenafil Vardenafil The risk or severity of hypertension can be decreased when Vardenafil is combined with Phenylephrine.
Alfuzosin Alfuzosin The therapeutic efficacy of Phenylephrine can be decreased when used in combination with Alfuzosin.
Tadalafil Tadalafil The risk or severity of hypertension can be decreased when Phenylephrine is combined with Tadalafil.
Frovatriptan Frovatriptan The metabolism of Frovatriptan can be increased when combined with Phenylephrine.
Protriptyline Protriptyline Protriptyline may increase the vasopressor activities of Phenylephrine.
Duloxetine Duloxetine Duloxetine may increase the tachycardic activities of Phenylephrine.
Trospium Trospium The risk or severity of Tachycardia can be increased when Trospium is combined with Phenylephrine.
Bosentan Bosentan Phenylephrine may decrease the antihypertensive activities of Bosentan.
Cinacalcet Cinacalcet The metabolism of Cinacalcet can be increased when combined with Phenylephrine.
Erlotinib Erlotinib The metabolism of Erlotinib can be increased when combined with Phenylephrine.
Solifenacin Solifenacin The risk or severity of hypertension can be increased when Phenylephrine is combined with Solifenacin.
Dextroamphetamine Dextroamphetamine Amphetamine may increase the hypertensive activities of Phenylephrine.
Entecavir Entecavir The metabolism of Entecavir can be increased when combined with Phenylephrine.
Isocarboxazid Isocarboxazid Isocarboxazid may increase the hypertensive activities of Phenylephrine.
Ramelteon Ramelteon The metabolism of Ramelteon can be increased when combined with Phenylephrine.
Darifenacin Darifenacin The risk or severity of Tachycardia can be increased when Phenylephrine is combined with Darifenacin.
Fentanyl Fentanyl The therapeutic efficacy of Fentanyl can be decreased when used in combination with Phenylephrine.
Rasagiline Rasagiline Rasagiline may increase the hypertensive activities of Phenylephrine.
Imatinib Imatinib The metabolism of Imatinib can be increased when combined with Phenylephrine.
Albuterol Albuterol The risk or severity of hypertension can be increased when Phenylephrine is combined with Salbutamol.
Paliperidone Paliperidone The therapeutic efficacy of Phenylephrine can be decreased when used in combination with Paliperidone.
Bortezomib Bortezomib The metabolism of Bortezomib can be increased when combined with Phenylephrine.
Primaquine Primaquine The metabolism of Primaquine can be increased when combined with Phenylephrine.
Aliskiren Aliskiren Phenylephrine may decrease the antihypertensive activities of Aliskiren.
Pemetrexed Injection Pemetrexed Injection The metabolism of Pemetrexed can be increased when combined with Phenylephrine.
Lisdexamfetamine Lisdexamfetamine The risk or severity of adverse effects can be increased when Phenylephrine is combined with Lisdexamfetamine.
Nabilone Nabilone The risk or severity of Tachycardia can be increased when Nabilone is combined with Phenylephrine.
Sorafenib Sorafenib The metabolism of Sorafenib can be increased when combined with Phenylephrine.
Dronabinol Dronabinol The risk or severity of Tachycardia can be increased when Dronabinol is combined with Phenylephrine.
Dasatinib Dasatinib The metabolism of Dasatinib can be increased when combined with Phenylephrine.
Mexiletine Mexiletine The metabolism of Mexiletine can be increased when combined with Phenylephrine.
Budesonide Budesonide The risk or severity of hypertension can be increased when Budesonide is combined with Phenylephrine.
Desmopressin Desmopressin The risk or severity of hypertension can be increased when Desmopressin is combined with Phenylephrine.
Desvenlafaxine Desvenlafaxine Desvenlafaxine may increase the tachycardic activities of Phenylephrine.
Nebivolol Nebivolol The therapeutic efficacy of Phenylephrine can be decreased when used in combination with Nebivolol.
Bendamustine Injection Bendamustine Injection The metabolism of Bendamustine can be increased when combined with Phenylephrine.
Flecainide Flecainide The metabolism of Flecainide can be increased when combined with Phenylephrine.
Praziquantel Praziquantel The metabolism of Praziquantel can be increased when combined with Phenylephrine.
Silodosin Silodosin The therapeutic efficacy of Phenylephrine can be decreased when used in combination with Silodosin.
Midazolam Midazolam The risk or severity of hypertension can be decreased when Midazolam is combined with Phenylephrine.
Eltrombopag Eltrombopag The metabolism of Eltrombopag can be increased when combined with Phenylephrine.
Milnacipran Milnacipran Milnacipran may increase the tachycardic activities of Phenylephrine.
Fesoterodine Fesoterodine The risk or severity of Tachycardia can be increased when Phenylephrine is combined with Fesoterodine.
Betaxolol Betaxolol The therapeutic efficacy of Phenylephrine can be decreased when used in combination with Betaxolol.
Iloperidone Iloperidone The therapeutic efficacy of Phenylephrine can be decreased when used in combination with Iloperidone.
Dronedarone Dronedarone The therapeutic efficacy of Phenylephrine can be decreased when used in combination with Dronedarone.
Pazopanib Pazopanib The metabolism of Pazopanib can be increased when combined with Phenylephrine.
Asenapine Asenapine The therapeutic efficacy of Phenylephrine can be decreased when used in combination with Asenapine.
Albendazole Albendazole The metabolism of Albendazole can be increased when combined with Phenylephrine.
Lurasidone Lurasidone The risk or severity of hypertension can be increased when Phenylephrine is combined with Lurasidone.
Vilazodone Vilazodone The risk or severity of hypertension can be increased when Phenylephrine is combined with Vilazodone.
Terbutaline Injection Terbutaline Injection The risk or severity of adverse effects can be increased when Phenylephrine is combined with Terbutaline.
Potassium Iodide Potassium Iodide The risk or severity of adverse effects can be increased when Phenylephrine is combined with Potassium Iodide.
Clobazam Clobazam The risk or severity of hypertension can be decreased when Clobazam is combined with Phenylephrine.
Axitinib Axitinib The metabolism of Axitinib can be increased when combined with Phenylephrine.
Cabergoline Cabergoline Cabergoline may increase the hypertensive and vasoconstricting activities of Phenylephrine.
Ambrisentan Ambrisentan Phenylephrine may decrease the antihypertensive activities of Ambrisentan.
Mirabegron Mirabegron The risk or severity of hypertension can be increased when Phenylephrine is combined with Mirabegron.
Corticotropin, Repository Injection Corticotropin, Repository Injection The risk or severity of hypertension can be increased when Corticotropin is combined with Phenylephrine.
Pomalidomide Pomalidomide The metabolism of Pomalidomide can be increased when combined with Phenylephrine.
Levomilnacipran Levomilnacipran Levomilnacipran may increase the tachycardic activities of Phenylephrine.
Vortioxetine Vortioxetine The risk or severity of hypertension can be increased when Phenylephrine is combined with Vortioxetine.
Perampanel Perampanel The metabolism of Perampanel can be increased when combined with Phenylephrine.
Avanafil Avanafil The risk or severity of hypertension can be decreased when Avanafil is combined with Phenylephrine.
Dapagliflozin Dapagliflozin The metabolism of Dapagliflozin can be increased when combined with Phenylephrine.
Apremilast Apremilast The metabolism of Apremilast can be increased when combined with Phenylephrine.
Droxidopa Droxidopa The therapeutic efficacy of Phenylephrine can be increased when used in combination with Droxidopa.
Methamphetamine Methamphetamine The metabolism of Phenylephrine can be decreased when combined with Metamfetamine.
Tasimelteon Tasimelteon The metabolism of Tasimelteon can be increased when combined with Phenylephrine.
Riociguat Riociguat Phenylephrine may decrease the antihypertensive activities of Riociguat.
Pirfenidone Pirfenidone The metabolism of Pirfenidone can be increased when combined with Phenylephrine.
Risperidone Injection Risperidone Injection The therapeutic efficacy of Phenylephrine can be decreased when used in combination with Risperidone.
Haloperidol Injection Haloperidol Injection The metabolism of Haloperidol can be increased when combined with Phenylephrine.
Macitentan Macitentan Phenylephrine may decrease the antihypertensive activities of Macitentan.
Flibanserin Flibanserin The risk or severity of hypertension can be increased when Phenylephrine is combined with Flibanserin.
Prednisolone Prednisolone The risk or severity of hypertension can be increased when Prednisolone is combined with Phenylephrine.
Brexpiprazole Brexpiprazole The therapeutic efficacy of Phenylephrine can be decreased when used in combination with Brexpiprazole.
Ziprasidone Injection Ziprasidone Injection The therapeutic efficacy of Phenylephrine can be decreased when used in combination with Ziprasidone.
Cariprazine Cariprazine The risk or severity of hypertension can be increased when Phenylephrine is combined with Cariprazine.
Dexamethasone Injection Dexamethasone Injection The risk or severity of hypertension can be increased when Dexamethasone is combined with Phenylephrine.
Midodrine Midodrine The risk or severity of adverse effects can be increased when Midodrine is combined with Phenylephrine.
Selexipag Selexipag Phenylephrine may decrease the antihypertensive activities of Selexipag.
Furosemide Injection Furosemide Injection Phenylephrine may decrease the antihypertensive activities of Furosemide.
Rucaparib Rucaparib The metabolism of Rucaparib can be increased when combined with Phenylephrine.
Parathyroid Hormone Injection Parathyroid Hormone Injection The risk or severity of adverse effects can be increased when Phenylephrine is combined with Parathyroid hormone.
Doxepin (Insomnia) Doxepin (Insomnia) Doxepin may increase the vasopressor activities of Phenylephrine.
Deflazacort Deflazacort The risk or severity of hypertension can be increased when Deflazacort is combined with Phenylephrine.
Safinamide Safinamide Safinamide may increase the hypertensive activities of Phenylephrine.
Abaloparatide Injection Abaloparatide Injection The risk or severity of adverse effects can be increased when Phenylephrine is combined with Abaloparatide.
Enasidenib Enasidenib The metabolism of Enasidenib can be increased when combined with Phenylephrine.
Fostamatinib Fostamatinib The risk or severity of hypertension can be decreased when Fostamatinib is combined with Phenylephrine.
Lofexidine Lofexidine The metabolism of Lofexidine can be increased when combined with Phenylephrine.
Binimetinib Binimetinib The metabolism of Binimetinib can be increased when combined with Phenylephrine.
Cannabidiol Cannabidiol The risk or severity of Tachycardia can be increased when Cannabidiol is combined with Phenylephrine.
Stiripentol Stiripentol The metabolism of Stiripentol can be increased when combined with Phenylephrine.
Siponimod Siponimod The risk or severity of hypertension can be increased when Phenylephrine is combined with Siponimod.
Acyclovir Ophthalmic Acyclovir Ophthalmic The metabolism of Acyclovir can be increased when combined with Phenylephrine.
Solriamfetol Solriamfetol The risk or severity of hypertension can be increased when Solriamfetol is combined with Phenylephrine.
Triclabendazole Triclabendazole The metabolism of Triclabendazole can be increased when combined with Phenylephrine.
Istradefylline Istradefylline The metabolism of Istradefylline can be increased when combined with Phenylephrine.
Selumetinib Selumetinib The metabolism of Selumetinib can be increased when combined with Phenylephrine.
Selpercatinib Selpercatinib The risk or severity of hypertension can be increased when Phenylephrine is combined with Selpercatinib.
Daratumumab and Hyaluronidase-fihj Injection Daratumumab and Hyaluronidase-fihj Injection The risk or severity of adverse effects can be increased when Hyaluronidase is combined with Phenylephrine.
Pertuzumab, Trastuzumab, and Hyaluronidase-zzxf Injection Pertuzumab, Trastuzumab, and Hyaluronidase-zzxf Injection The risk or severity of adverse effects can be increased when Hyaluronidase is combined with Phenylephrine.
Naxitamab-gqgk Injection Naxitamab-gqgk Injection The risk or severity of hypertension can be increased when Phenylephrine is combined with Naxitamab.
Theophylline Theophylline The metabolism of Theophylline can be increased when combined with Phenylephrine.
Fenoprofen Fenoprofen The risk or severity of hypertension can be increased when Phenylephrine is combined with Fenoprofen.
Indomethacin Indomethacin The risk or severity of hypertension can be increased when Indomethacin is combined with Phenylephrine.
Mefenamic Acid Mefenamic Acid The risk or severity of hypertension can be increased when Phenylephrine is combined with Mefenamic acid.
Naproxen Naproxen The metabolism of Naproxen can be increased when combined with Phenylephrine.
Tolmetin Tolmetin The risk or severity of hypertension can be increased when Phenylephrine is combined with Tolmetin.
Sulindac Sulindac The risk or severity of hypertension can be increased when Phenylephrine is combined with Sulindac.
Trazodone Trazodone The therapeutic efficacy of Phenylephrine can be decreased when used in combination with Trazodone.
Methsuximide Methsuximide The risk or severity of hypertension can be decreased when Methsuximide is combined with Phenylephrine.
Diethylpropion Diethylpropion The risk or severity of adverse effects can be increased when Phenylephrine is combined with Diethylpropion.
Chlorpromazine Chlorpromazine The therapeutic efficacy of Phenylephrine can be decreased when used in combination with Chlorpromazine.
Diazepam Diazepam The risk or severity of hypertension can be decreased when Diazepam is combined with Phenylephrine.
Oxazepam Oxazepam The risk or severity of hypertension can be decreased when Oxazepam is combined with Phenylephrine.
Flurazepam Flurazepam The risk or severity of hypertension can be decreased when Flurazepam is combined with Phenylephrine.
Clorazepate Clorazepate The risk or severity of hypertension can be decreased when Clorazepic acid is combined with Phenylephrine.
Lorazepam Lorazepam The risk or severity of hypertension can be decreased when Lorazepam is combined with Phenylephrine.
Phenoxybenzamine Phenoxybenzamine The therapeutic efficacy of Phenylephrine can be decreased when used in combination with Phenoxybenzamine.
Carmustine Carmustine The metabolism of Carmustine can be increased when combined with Phenylephrine.
Chlordiazepoxide Chlordiazepoxide The risk or severity of hypertension can be decreased when Chlordiazepoxide is combined with Phenylephrine.
Bromocriptine Bromocriptine Bromocriptine may increase the hypertensive and vasoconstricting activities of Phenylephrine.
Metaproterenol Metaproterenol The risk or severity of adverse effects can be increased when Phenylephrine is combined with Orciprenaline.
Tranylcypromine Tranylcypromine Tranylcypromine may increase the hypertensive activities of Phenylephrine.
Phenelzine Phenelzine Phenelzine may increase the hypertensive activities of Phenylephrine.
Procarbazine Procarbazine Procarbazine may increase the hypertensive activities of Phenylephrine.
Ergoloid Mesylates Ergoloid Mesylates Ergoloid mesylate may increase the hypertensive and vasoconstricting activities of Phenylephrine.
Thioridazine Thioridazine The therapeutic efficacy of Phenylephrine can be decreased when used in combination with Thioridazine.
Trifluoperazine Trifluoperazine The therapeutic efficacy of Phenylephrine can be decreased when used in combination with Trifluoperazine.
Oxybutynin Oxybutynin The risk or severity of Tachycardia can be increased when Phenylephrine is combined with Oxybutynin.
Benztropine Benztropine The risk or severity of Tachycardia can be increased when Benzatropine is combined with Phenylephrine.
Maprotiline Maprotiline The metabolism of Maprotiline can be increased when combined with Phenylephrine.
Trihexyphenidyl Trihexyphenidyl The risk or severity of Tachycardia can be increased when Trihexyphenidyl is combined with Phenylephrine.
Orphenadrine Orphenadrine The risk or severity of Tachycardia can be increased when Phenylephrine is combined with Orphenadrine.
Perphenazine Perphenazine The metabolism of Perphenazine can be increased when combined with Phenylephrine.
Azathioprine Azathioprine The metabolism of Azathioprine can be increased when combined with Phenylephrine.
Phentermine Phentermine The metabolism of Phenylephrine can be decreased when combined with Phentermine.
Methylphenidate Methylphenidate The risk or severity of hypertension can be increased when Phenylephrine is combined with Methylphenidate.
Amoxapine Amoxapine Amoxapine may increase the vasopressor activities of Phenylephrine.
Sulfasalazine Sulfasalazine The risk or severity of hypertension can be increased when Phenylephrine is combined with Sulfasalazine.
Hydrocortisone Hydrocortisone The risk or severity of hypertension can be increased when Hydrocortisone is combined with Phenylephrine.
Methyldopa Methyldopa Phenylephrine may decrease the antihypertensive activities of Methyldopa.
Clonidine Clonidine The metabolism of Clonidine can be increased when combined with Phenylephrine.
Prazosin Prazosin The therapeutic efficacy of Phenylephrine can be decreased when used in combination with Prazosin.
Hydralazine Hydralazine Phenylephrine may decrease the antihypertensive activities of Hydralazine.
Warfarin Warfarin The metabolism of Warfarin can be increased when combined with Phenylephrine.
Clonazepam Clonazepam The risk or severity of hypertension can be decreased when Clonazepam is combined with Phenylephrine.
Loperamide Loperamide The risk or severity of hypertension can be decreased when Loperamide is combined with Phenylephrine.
Meclofenamate Meclofenamate The risk or severity of hypertension can be increased when Phenylephrine is combined with Meclofenamic acid.
Quinine Quinine The metabolism of Quinine can be increased when combined with Phenylephrine.
Ethosuximide Ethosuximide The risk or severity of hypertension can be decreased when Ethosuximide is combined with Phenylephrine.
Triamterene Triamterene The metabolism of Triamterene can be increased when combined with Phenylephrine.
Chlorothiazide Chlorothiazide Phenylephrine may decrease the antihypertensive activities of Chlorothiazide.
Chlorthalidone Chlorthalidone Phenylephrine may decrease the antihypertensive activities of Chlorthalidone.
Metolazone Metolazone Phenylephrine may decrease the antihypertensive activities of Metolazone.
Desipramine Desipramine Desipramine may increase the vasopressor activities of Phenylephrine.
Amitriptyline Amitriptyline Amitriptyline may increase the vasopressor activities of Phenylephrine.
Imipramine Imipramine Imipramine may increase the vasopressor activities of Phenylephrine.
Quinidine Quinidine The therapeutic efficacy of Phenylephrine can be decreased when used in combination with Quinidine.
Disopyramide Disopyramide The metabolism of Disopyramide can be increased when combined with Phenylephrine.
Tamoxifen Tamoxifen The metabolism of Tamoxifen can be increased when combined with Phenylephrine.
Levothyroxine Levothyroxine The risk or severity of adverse effects can be increased when Phenylephrine is combined with Levothyroxine.
Liothyronine Liothyronine The risk or severity of adverse effects can be increased when Phenylephrine is combined with Liothyronine.
Methimazole Methimazole The risk or severity of adverse effects can be increased when Phenylephrine is combined with Methimazole.
Propylthiouracil Propylthiouracil The risk or severity of adverse effects can be increased when Phenylephrine is combined with Propylthiouracil.
Cyclobenzaprine Cyclobenzaprine The metabolism of Cyclobenzaprine can be increased when combined with Phenylephrine.
Cyproheptadine Cyproheptadine The risk or severity of Tachycardia can be increased when Phenylephrine is combined with Cyproheptadine.
Hydrochlorothiazide Hydrochlorothiazide Phenylephrine may decrease the antihypertensive activities of Hydrochlorothiazide.
Chlorzoxazone Chlorzoxazone The metabolism of Chlorzoxazone can be increased when combined with Phenylephrine.
Propranolol (Cardiovascular) Propranolol (Cardiovascular) The therapeutic efficacy of Phenylephrine can be decreased when used in combination with Propranolol.
Minoxidil Minoxidil Phenylephrine may decrease the antihypertensive activities of Minoxidil.
Pseudoephedrine Pseudoephedrine The metabolism of Phenylephrine can be decreased when combined with Pseudoephedrine.
Nortriptyline Nortriptyline Nortriptyline may increase the vasopressor activities of Phenylephrine.
Spironolactone Spironolactone The therapeutic efficacy of Phenylephrine can be decreased when used in combination with Spironolactone.
Mercaptopurine Mercaptopurine The risk or severity of adverse effects can be increased when Phenylephrine is combined with Mercaptopurine.
Nadolol Nadolol The therapeutic efficacy of Phenylephrine can be decreased when used in combination with Nadolol.
Oxytocin Injection Oxytocin Injection The risk or severity of hypertension can be increased when Oxytocin is combined with Phenylephrine.
Flavoxate Flavoxate The risk or severity of Tachycardia can be increased when Phenylephrine is combined with Flavoxate.
Fluorouracil Injection Fluorouracil Injection The metabolism of Fluorouracil can be increased when combined with Phenylephrine.
Dacarbazine Dacarbazine The metabolism of Dacarbazine can be increased when combined with Phenylephrine.
Calcitonin Salmon Injection Calcitonin Salmon Injection The risk or severity of adverse effects can be increased when Phenylephrine is combined with Salmon calcitonin.
Captopril Captopril Phenylephrine may decrease the antihypertensive activities of Captopril.
Dipyridamole Dipyridamole The risk or severity of hypertension can be decreased when Dipyridamole is combined with Phenylephrine.
Isoxsuprine Isoxsuprine The risk or severity of adverse effects can be increased when Phenylephrine is combined with Isoxsuprine.
Metoprolol Metoprolol The therapeutic efficacy of Phenylephrine can be decreased when used in combination with Metoprolol.
Thiothixene Thiothixene The metabolism of Thiothixene can be increased when combined with Phenylephrine.
Salsalate Salsalate The risk or severity of hypertension can be increased when Phenylephrine is combined with Salsalate.
Alprazolam Alprazolam The risk or severity of hypertension can be decreased when Alprazolam is combined with Phenylephrine.
Temazepam Temazepam The risk or severity of hypertension can be decreased when Temazepam is combined with Phenylephrine.
Triazolam Triazolam The risk or severity of hypertension can be decreased when Triazolam is combined with Phenylephrine.
Dicyclomine Dicyclomine The risk or severity of Tachycardia can be increased when Phenylephrine is combined with Dicyclomine.
Hyoscyamine Hyoscyamine The risk or severity of Tachycardia can be increased when Phenylephrine is combined with Hyoscyamine.
Propantheline Propantheline The risk or severity of Tachycardia can be increased when Phenylephrine is combined with Propantheline.
Diltiazem Diltiazem The risk or severity of hypertension can be decreased when Phenylephrine is combined with Diltiazem.
Nifedipine Nifedipine The risk or severity of hypertension can be decreased when Phenylephrine is combined with Nifedipine.
Timolol Timolol The therapeutic efficacy of Phenylephrine can be decreased when used in combination with Timolol.
Verapamil Verapamil The risk or severity of hypertension can be decreased when Verapamil is combined with Phenylephrine.
Atenolol Atenolol The therapeutic efficacy of Phenylephrine can be decreased when used in combination with Atenolol.
Pindolol Pindolol The therapeutic efficacy of Phenylephrine can be decreased when used in combination with Pindolol.
Diflunisal Diflunisal The risk or severity of hypertension can be increased when Phenylephrine is combined with Diflunisal.
Piroxicam Piroxicam The risk or severity of hypertension can be increased when Phenylephrine is combined with Piroxicam.
Etoposide Etoposide The metabolism of Etoposide can be increased when combined with Phenylephrine.
Glyburide Glyburide The therapeutic efficacy of Glyburide can be decreased when used in combination with Phenylephrine.
Indapamide Indapamide Phenylephrine may decrease the antihypertensive activities of Indapamide.
Pentoxifylline Pentoxifylline The risk or severity of hypertension can be decreased when Phenylephrine is combined with Pentoxifylline.
Labetalol Labetalol The therapeutic efficacy of Phenylephrine can be decreased when used in combination with Labetalol.
Guanabenz Guanabenz The metabolism of Guanabenz can be increased when combined with Phenylephrine.
Ketoprofen Ketoprofen The risk or severity of hypertension can be increased when Phenylephrine is combined with Ketoprofen.
Pimozide Pimozide The metabolism of Pimozide can be increased when combined with Phenylephrine.
Enalapril Enalapril Phenylephrine may decrease the antihypertensive activities of Enalapril.
Flurbiprofen Flurbiprofen The risk or severity of hypertension can be increased when Phenylephrine is combined with Flurbiprofen.
Amiodarone Amiodarone The risk or severity of hypertension can be decreased when Phenylephrine is combined with Amiodarone.
Buspirone Buspirone The risk or severity of hypertension can be increased when Phenylephrine is combined with Buspirone.
Mesalamine Mesalamine The risk or severity of hypertension can be increased when Mesalazine is combined with Phenylephrine.
Diclofenac Diclofenac The metabolism of Diclofenac can be increased when combined with Phenylephrine.
Fluoxetine Fluoxetine The metabolism of Fluoxetine can be increased when combined with Phenylephrine.
Nimodipine Nimodipine The risk or severity of hypertension can be decreased when Phenylephrine is combined with Nimodipine.
Clozapine Clozapine The therapeutic efficacy of Phenylephrine can be decreased when used in combination with Clozapine.
Estazolam Estazolam The risk or severity of hypertension can be decreased when Estazolam is combined with Phenylephrine.
Benazepril Benazepril Phenylephrine may decrease the antihypertensive activities of Benazepril.
Etodolac Etodolac The risk or severity of hypertension can be increased when Phenylephrine is combined with Etodolac.
Felodipine Felodipine The risk or severity of hypertension can be decreased when Felodipine is combined with Phenylephrine.
Fosinopril Fosinopril Phenylephrine may decrease the antihypertensive activities of Fosinopril.
Nabumetone Nabumetone The metabolism of Nabumetone can be increased when combined with Phenylephrine.
Quinapril Quinapril Phenylephrine may decrease the antihypertensive activities of Quinapril.
Ramipril Ramipril Phenylephrine may decrease the antihypertensive activities of Ramipril.
Amlodipine Amlodipine The risk or severity of hypertension can be decreased when Phenylephrine is combined with Amlodipine.
Lisinopril Lisinopril Phenylephrine may decrease the antihypertensive activities of Lisinopril.
Oxaprozin Oxaprozin The risk or severity of hypertension can be increased when Phenylephrine is combined with Oxaprozin.
Sotalol Sotalol The therapeutic efficacy of Phenylephrine can be decreased when used in combination with Sotalol.
Bisoprolol Bisoprolol The therapeutic efficacy of Phenylephrine can be decreased when used in combination with Bisoprolol.
Zolpidem Zolpidem The metabolism of Zolpidem can be increased when combined with Phenylephrine.
Doxazosin Doxazosin The therapeutic efficacy of Phenylephrine can be decreased when used in combination with Doxazosin.
Terazosin Terazosin The therapeutic efficacy of Phenylephrine can be decreased when used in combination with Terazosin.
Isradipine Isradipine The risk or severity of hypertension can be decreased when Phenylephrine is combined with Isradipine.
Venlafaxine Venlafaxine Venlafaxine may increase the tachycardic activities of Phenylephrine.
Fluvoxamine Fluvoxamine The metabolism of Fluvoxamine can be increased when combined with Phenylephrine.
Nefazodone Nefazodone The therapeutic efficacy of Phenylephrine can be decreased when used in combination with Nefazodone.
Lamotrigine Lamotrigine The risk or severity of hypertension can be decreased when Phenylephrine is combined with Lamotrigine.
Losartan Losartan Phenylephrine may decrease the antihypertensive activities of Losartan.
Tramadol Tramadol The risk or severity of Tachycardia can be increased when Tramadol is combined with Phenylephrine.
Moexipril Moexipril Phenylephrine may decrease the antihypertensive activities of Moexipril.
Nicardipine Nicardipine The risk or severity of hypertension can be decreased when Nicardipine is combined with Phenylephrine.
Nisoldipine Nisoldipine The risk or severity of hypertension can be decreased when Phenylephrine is combined with Nisoldipine.
Riluzole Riluzole The metabolism of Riluzole can be increased when combined with Phenylephrine.
Clomipramine Clomipramine Clomipramine may increase the vasopressor activities of Phenylephrine.
Mirtazapine Mirtazapine The metabolism of Mirtazapine can be increased when combined with Phenylephrine.
Trandolapril Trandolapril Phenylephrine may decrease the antihypertensive activities of Trandolapril.
Zileuton Zileuton The metabolism of Zileuton can be increased when combined with Phenylephrine.
Valsartan Valsartan Phenylephrine may decrease the antihypertensive activities of Valsartan.
Carvedilol Carvedilol The risk or severity of hypertension can be decreased when Carvedilol is combined with Phenylephrine.
Flutamide Flutamide The metabolism of Flutamide can be increased when combined with Phenylephrine.
Selegiline Selegiline Selegiline may increase the hypertensive activities of Phenylephrine.
Propafenone Propafenone The therapeutic efficacy of Phenylephrine can be decreased when used in combination with Propafenone.
Irbesartan Irbesartan Phenylephrine may decrease the antihypertensive activities of Irbesartan.
Tamsulosin Tamsulosin The therapeutic efficacy of Phenylephrine can be decreased when used in combination with Tamsulosin.
Ropinirole Ropinirole The metabolism of Ropinirole can be increased when combined with Phenylephrine.
Finasteride Finasteride The risk or severity of hypertension can be increased when Phenylephrine is combined with Finasteride.
Quetiapine Quetiapine The therapeutic efficacy of Phenylephrine can be decreased when used in combination with Quetiapine.
Paroxetine Paroxetine The metabolism of Paroxetine can be increased when combined with Phenylephrine.
Efavirenz Efavirenz The metabolism of Efavirenz can be increased when combined with Phenylephrine.
Sildenafil Sildenafil The risk or severity of hypertension can be decreased when Sildenafil is combined with Phenylephrine.
Celecoxib Celecoxib The risk or severity of hypertension can be increased when Phenylephrine is combined with Celecoxib.
Tolterodine Tolterodine The risk or severity of Tachycardia can be increased when Phenylephrine is combined with Tolterodine.
Balsalazide Balsalazide The risk or severity of hypertension can be increased when Phenylephrine is combined with Balsalazide.
Terbinafine Terbinafine The metabolism of Terbinafine can be increased when combined with Phenylephrine.

* This branded product is no longer on the market. Generic alternatives may be available.

** These products are not currently approved by the FDA for safety, effectiveness, and quality. Federal law generally requires that prescription drugs in the U.S. be shown to be both safe and effective prior to marketing. Please see the FDA website for more information on unapproved drugs (http://www.fda.gov/AboutFDA/Transparency/Basics/ucm213030.htm ) and the approval process (http://www.fda.gov/Drugs/ResourcesForYou/Consumers/ucm054420.htm ).

Content provided by: AHFS® Patient Medication Information™. © Copyright, 2021. The American Society of Health-System Pharmacists