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Guaifenesin 20 MG/ML Oral Solution — RxCUI 310604

RxNorm drug concept · Semantic clinical drug
RxCUI 310604 Semantic clinical drug · SCD ● Current RxNorm concept 50 FDA products 67 package NDCs Snapshot Jul 14, 2026

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI310604
Official nameGuaifenesin 20 MG/ML Oral Solution
Concept typeSemantic clinical drug (SCD)
RxNorm statusCurrent RxNorm concept
Also known asguaifenesin 100 MG per 5 ML Oral Syrup; guaiFENesin 100 MG in 5 mL Oral Solution; guaifenesin 100 MG per 5 ML Oral Solution; guaifenesin 200 MG per 10 ML Oral Solution; guaifenesin 300 MG per 15 ML Oral Solution +1 more
FDA products mapped50
Package NDCs mapped67
Reported Medicaid activity (SDUD)244,208 prescriptions · 38 state & territory Medicaid programs · latest period Q4 2025
RxNorm release07/06/2026
Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Guaifenesin: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist
  • Guaifenesin is what's called an expectorant — it works to thin and loosen the mucus sitting in your chest and airways. That makes it easier to cough the mucus up and out, so instea...
  • What exactly does guaifenesin do for my cough?
  • Guaifenesin is meant for short-term use. If your cough isn't getting better after 7 days, keeps coming back, or shows up alongside a fever, rash, or a headache that won't go away,...
  • How long can I take it before I should call my doctor?
📖 Read our full Guaifenesin guide →

🕸️ Concept Web — How Guaifenesin 20 MG/ML Oral Solution Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.
This page's concept Guaifenesin 20 MG/ML Oral Solution RxCUI 310604

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

  1. Ingredients 1

    The active substance itself — no strength, form, or brand attached yet.

    • Guaifenesin 5032
  2. Brand names 7

    The same medicine's trade names. A brand name alone says nothing about strength or form.

    • Cough Out 1099021
    • Diabetic Tussin EX 992209
    • Mucinex 352777
    • Robafen 219688
    • Rompe Pecho 1112202
    • Scot-Tussin 219820
    • Siltussin 219906
  3. Dose forms 27

    The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.

    • Guaifenesin Oral Solution 372358
    • Guaifenesin Oral Liquid Product 1159703
    • Guaifenesin Oral Product 1159704
    • Guaifenesin Oral Solution [Cough Out] 1099023
    • Guaifenesin Oral Solution [Diabetic Tussin EX] 992211
    • Guaifenesin Oral Solution [Mucinex] 669125
    • Guaifenesin Oral Solution [Robafen] 364627
    • Guaifenesin Oral Solution [Rompe Pecho] 1112204
    • +19 more in this family
  4. Clinical & branded drugs 15

    Ingredient + strength + dose form. These are the concepts real FDA products actually carry.

Showing up to 8 concepts per family — 24 of 50 stored related concepts drawn.
These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

  • Guaifenesin 20 MG/ML SCDC · 316011
  • Guaifenesin Oral Solution SCDF · 372358
  • Guaifenesin Oral Liquid Product SCDG · 1159703
  • Guaifenesin Oral Product SCDG · 1159704

Brand-Name Concepts

📦 FDA Products & Package NDCs

50 products · 67 package NDCs
67 package NDCs map to RxCUI 310604 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.
Package NDC Package Brand / generic name Labeler Marketing start
00121-0744-04 118 mL in 1 BOTTLE (0121-0744-04) GUAIFENESIN PAI Holdings, LLC dba PAI Pharma 2002-09-01
00121-0744-08 237 mL in 1 BOTTLE (0121-0744-08) GUAIFENESIN PAI Holdings, LLC dba PAI Pharma 2002-09-01
00121-0744-16 473 mL in 1 BOTTLE (0121-0744-16) GUAIFENESIN PAI Holdings, LLC dba PAI Pharma 2002-09-01
00121-1488-00 10 TRAY in 1 CASE (0121-1488-00) / 10 CUP, UNIT-DOSE in 1 T... GUAIFENESIN PAI Holdings, LLC dba PAI Pharma 2002-09-01
00121-1744-00 10 TRAY in 1 CASE (0121-1744-00) / 10 CUP, UNIT-DOSE in 1 T... GUAIFENESIN PAI Holdings, LLC dba PAI Pharma 2002-09-01
00121-2232-00 10 TRAY in 1 CASE (0121-2232-00) / 10 CUP, UNIT-DOSE in 1 T... GUAIFENESIN PAI Holdings, LLC dba PAI Pharma 2002-09-01
00363-7043-08 1 BOTTLE in 1 CARTON (0363-7043-08) / 237 mL in 1 BOTTLE Walgreen Cherry WALGREEN COMPANY 2022-11-01
00363-7504-04 1 BOTTLE in 1 CARTON (0363-7504-04) / 120 mL in 1 BOTTLE Childrens Chest Congestion Relief WALGREENS COMPANY 2020-01-29
00536-1314-85 473 mL in 1 BOTTLE (0536-1314-85) Chest Congestion Relief RUGBY LABORATORIES 2020-10-01
46122-0785-29 1 BOTTLE in 1 CARTON (46122-785-29) / 118 mL in 1 BOTTLE Good Neighbor Adult Tussin Mucus and chest congestion AMERISOURCE BERGEN 2024-06-24
46122-0785-34 1 BOTTLE in 1 CARTON (46122-785-34) / 237 mL in 1 BOTTLE Good Neighbor Adult Tussin Mucus and chest congestion AMERISOURCE BERGEN 2024-06-24
50090-6542-00 118 mL in 1 BOTTLE (50090-6542-0) Tusnel EX A-S Medication Solutions 2023-07-05
51316-0437-08 1 BOTTLE in 1 CARTON (51316-437-08) / 237 mL in 1 BOTTLE CVS Adult Mucus plus Chest Congestion CVS PHARMACY 2024-03-11
51316-0743-08 1 BOTTLE in 1 CARTON (51316-743-08) / 237 mL in 1 BOTTLE CVS Adult Mucus chest congestion CVS PHARMACY 2023-02-17
53943-0507-26 237 mL in 1 BOTTLE (53943-507-26) Tussin Discount Drug Mart 2014-11-19
53943-0511-24 118 mL in 1 BOTTLE (53943-511-24) Childrens Chest Congestion Relief Grape Discount Drug Mart 2015-02-04
54859-0507-04 118 mL in 1 BOTTLE (54859-507-04) Tusnel EX Llorens Pharmaceutical International Division, Inc. 2019-05-01
54859-0510-16 473 mL in 1 BOTTLE (54859-510-16) Llorens Care Tussin Llorens Pharmaceutical International Division, Inc. 2025-12-01
55154-5780-05 5 CUP, UNIT-DOSE in 1 BAG (55154-5780-5) / 10 mL in 1 CUP,... GUAIFENESIN Cardinal Health 107, LLC 2002-09-01
55154-9450-05 5 CUP, UNIT-DOSE in 1 BAG (55154-9450-5) / 5 mL in 1 CUP, U... GUAIFENESIN Cardinal Health 107, LLC 2002-09-01
57237-0359-12 118 mL in 1 BOTTLE (57237-359-12) Mucolyte Rising Pharma Holdings, Inc. 2025-12-22
57237-0359-16 473 mL in 1 BOTTLE (57237-359-16) Mucolyte Rising Pharma Holdings, Inc. 2025-12-22
57896-0293-16 473 mL in 1 BOTTLE (57896-293-16) Geri-Tussin Geri-Care Pharmaceuticals, Corp 2023-03-31
57896-0693-04 118 mL in 1 BOTTLE (57896-693-04) Geri-Tussin Geri-Care Pharmaceuticals, Corp 2025-06-05
57896-0693-08 237 mL in 1 BOTTLE (57896-693-08) Geri-Tussin Geri-Care Pharmaceuticals, Corp 2025-12-01
57896-0693-16 473 mL in 1 BOTTLE (57896-693-16) Geri-Tussin Geri-Care Pharmaceuticals, Corp 2019-05-01
58593-0255-06 178 mL in 1 BOTTLE (58593-255-06) Cough Out Efficient Laboratories Inc. 1997-07-01
58593-0265-06 178 mL in 1 BOTTLE (58593-265-06) Rompe Pecho SF Efficient Laboratories, Inc. 1999-03-01
58593-0829-04 118 mL in 1 BOTTLE (58593-829-04) Rompe Pecho EX Efficient Laboratories Inc 2019-04-01
58593-0829-06 178 mL in 1 BOTTLE (58593-829-06) Rompe Pecho EX Efficient Laboratories Inc 2015-01-01
58657-0508-16 473 mL in 1 BOTTLE (58657-508-16) Guaifenesin Method Pharmaceuticals, LLC 2024-04-01
58657-0509-16 473 mL in 1 BOTTLE (58657-509-16) Guaifenesin Method Pharmaceuticals, LLC 2016-02-09
60687-0852-17 10 TRAY in 1 CASE (60687-852-17) / 10 CUP, UNIT-DOSE in 1 T... Guaifenesin American Health Packaging 2024-10-20
60687-0863-56 10 TRAY in 1 CASE (60687-863-56) / 10 CUP, UNIT-DOSE in 1 T... Guaifenesin American Health Packaging 2024-10-20
60687-0874-16 10 TRAY in 1 CASE (60687-874-16) / 10 CUP, UNIT-DOSE in 1 T... Guaifenesin American Health Packaging 2024-10-20
63824-0537-66 180 mL in 1 BOTTLE (63824-537-66) Mucinex Fast-Max Chest Congestion Honey and Berry Flavor Reckitt Benckiser LLC 2020-06-01
63868-0770-04 1 BOTTLE in 1 CARTON (63868-770-04) / 118 mL in 1 BOTTLE Childrens Mucus Relief Chest Congestion Chain Drug Manufacturing Assn 2015-10-19
66424-0563-16 473 mL in 1 BOTTLE (66424-563-16) SDA Laboratories Tussin SDA Laboratories, Inc. 2024-12-01
68163-0743-04 1 BOTTLE in 1 CARTON (68163-743-04) / 118 mL in 1 BOTTLE DRx Choice Fruit Punch Raritan Pharmaceuticals Inc 2019-05-15
69230-0332-23 1 BOTTLE in 1 CARTON (69230-332-23) / 237 mL in 1 BOTTLE Adult Tussin Camber Consumer Care 2025-05-20
69618-0068-54 118 mL in 1 BOTTLE (69618-068-54) Reliable-1 Tussin RELIABLE 1 LABORATORIES LLC 2024-12-01
69822-0200-02 118 mL in 1 BOTTLE (69822-200-02) Akin Southern Sales & Service, Inc. 2015-01-04
70677-1186-01 1 BOTTLE in 1 CARTON (70677-1186-1) / 118 mL in 1 BOTTLE Tussin Strategic Sourcing Services 2023-08-09
70677-1186-02 1 BOTTLE in 1 CARTON (70677-1186-2) / 237 mL in 1 BOTTLE Tussin Strategic Sourcing Services 2023-08-09
71399-0024-04 1 BOTTLE, PLASTIC in 1 PACKAGE (71399-0024-4) / 118 mL in 1... MAX Tussin Mucus and Chest Congestion Sugar Free Akron Pharma Inc. 2023-05-15
71399-0024-06 473 mL in 1 BOTTLE, PLASTIC (71399-0024-6) MAX Tussin Mucus and Chest Congestion Sugar Free Akron Pharma Inc. 2023-05-15
71399-0024-08 1 BOTTLE, PLASTIC in 1 PACKAGE (71399-0024-8) / 236 mL in 1... MAX Tussin Mucus and Chest Congestion Sugar Free Akron Pharma Inc. 2023-05-15
71399-0054-04 1 BOTTLE in 1 PACKAGE (71399-0054-4) / 118 mL in 1 BOTTLE MAX Tussin Mucus and Chest Congestion Akron Pharma Inc. 2023-11-03
71399-0054-06 473 mL in 1 BOTTLE (71399-0054-6) MAX Tussin Mucus and Chest Congestion Akron Pharma Inc. 2023-11-03
71399-0054-08 1 BOTTLE in 1 PACKAGE (71399-0054-8) / 236 mL in 1 BOTTLE MAX Tussin Mucus and Chest Congestion Akron Pharma Inc. 2023-11-03
Observed labelers: Akron Pharma Inc. (6) · PAI Holdings, LLC dba PAI Pharma (6) · Geri-Care Pharmaceuticals, Corp (4) · AARNA USA, Inc. (3) · Aldama Pharmaceuticals, Inc (3) · American Health Packaging (3) · +31 more — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7
openFDA export observedJul 14, 2026
RxNorm release07/06/2026
Methodology2026-07-full-catalog-v1
  • A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
  • Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
  • Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
  • Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.
This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.