Home › NDC Lookup › RxCUI directory › RxCUI 313096

Spironolactone 25 MG Oral Tablet — RxCUI 313096

RxNorm drug concept · Semantic clinical drug
RxCUI 313096 Semantic clinical drug · SCD ● Current RxNorm concept 114 FDA products 355 package NDCs Snapshot Jul 14, 2026

This page is curated, coded, and maintained by

Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI313096
Official nameSpironolactone 25 MG Oral Tablet
Concept typeSemantic clinical drug (SCD)
RxNorm statusCurrent RxNorm concept
FDA products mapped114
Package NDCs mapped355
Reported Medicaid activity (SDUD)2,512,131 prescriptions · 52 state & territory Medicaid programs · latest period Q4 2025
RxNorm release07/06/2026
Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Spironolactone: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist
  • Spironolactone is used for a few different conditions depending on the form you're prescribed. Most commonly, it treats heart failure, high blood pressure, and fluid buildup (swell...
  • What is spironolactone actually used for?
  • Either is fine — but pick one and stick with it. Food can nearly double how much spironolactone your body absorbs, so if you take it with food some days and without food others, yo...
  • Should I take spironolactone with food or on an empty stomach?
📖 Read our full Spironolactone guide →

🕸️ Concept Web — How Spironolactone 25 MG Oral Tablet Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.
This page's concept Spironolactone 25 MG Oral Tablet RxCUI 313096

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

  1. Ingredients 1

    The active substance itself — no strength, form, or brand attached yet.

    • Spironolactone 9997
  2. Brand names 1

    The same medicine's trade names. A brand name alone says nothing about strength or form.

    • Aldactone 151317
  3. Dose forms 9

    The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.

    • Spironolactone Oral Tablet 373946
    • Spironolactone Oral Product 1161122
    • Spironolactone Pill 1161123
    • Spironolactone Oral Tablet [Aldactone] 368071
    • Aldactone Oral Product 1174848
    • Aldactone Pill 1174849
    • Oral Tablet 317541
    • Oral Product 1151131
    • +1 more in this family
  4. Clinical & branded drugs 3

    Ingredient + strength + dose form. These are the concepts real FDA products actually carry.

Showing up to 8 concepts per family — 13 of 14 stored related concepts drawn.
These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

  • Spironolactone 25 MG SCDC · 316728
  • Spironolactone Oral Tablet SCDF · 373946
  • Spironolactone Oral Product SCDG · 1161122
  • Spironolactone Pill SCDG · 1161123

Brand-Name Concepts

  • Spironolactone 25 MG Oral Tablet [Aldactone] SBD · 200820
  • Spironolactone 25 MG [Aldactone] SBDC · 565468
  • Spironolactone Oral Tablet [Aldactone] SBDF · 368071
  • Aldactone Oral Product SBDG · 1174848
  • Aldactone Pill SBDG · 1174849
  • Aldactone BN · 151317

📦 FDA Products & Package NDCs

114 products · 355 package NDCs
355 package NDCs map to RxCUI 313096 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.
Package NDC Package Brand / generic name Labeler Marketing start
00025-1001-31 100 TABLET, FILM COATED in 1 BOTTLE (0025-1001-31) Aldactone Pfizer Laboratories Div Pfizer Inc 1960-01-21
00025-1031-31 100 TABLET, FILM COATED in 1 BOTTLE (0025-1031-31) Aldactone Pfizer Laboratories Div Pfizer Inc 1960-01-21
00025-1041-31 100 TABLET, FILM COATED in 1 BOTTLE (0025-1041-31) Aldactone Pfizer Laboratories Div Pfizer Inc 1960-01-21
00378-0243-01 100 TABLET, FILM COATED in 1 BOTTLE, PLASTIC (0378-0243-01) Spironolactone Mylan Pharmaceuticals Inc. 2002-01-22
00378-0243-05 500 TABLET, FILM COATED in 1 BOTTLE, PLASTIC (0378-0243-05) Spironolactone Mylan Pharmaceuticals Inc. 2009-06-26
00378-0437-01 100 TABLET, FILM COATED in 1 BOTTLE, PLASTIC (0378-0437-01) Spironolactone Mylan Pharmaceuticals Inc. 2002-01-22
00378-2146-01 100 TABLET, FILM COATED in 1 BOTTLE, PLASTIC (0378-2146-01) Spironolactone Mylan Pharmaceuticals Inc. 1981-02-03
00378-2146-05 500 TABLET, FILM COATED in 1 BOTTLE, PLASTIC (0378-2146-05) Spironolactone Mylan Pharmaceuticals Inc. 1981-02-03
00615-8451-05 15 TABLET in 1 BLISTER PACK (0615-8451-05) SPIRONOLACTONE NCS HealthCare of KY, LLC dba Vangard Labs 2023-04-13
00615-8451-39 30 TABLET in 1 BLISTER PACK (0615-8451-39) SPIRONOLACTONE NCS HealthCare of KY, LLC dba Vangard Labs 2023-04-13
00615-8452-39 30 TABLET in 1 BLISTER PACK (0615-8452-39) SPIRONOLACTONE NCS HealthCare of KY, LLC dba Vangard Labs 2023-03-01
00904-6927-61 100 BLISTER PACK in 1 CARTON (0904-6927-61) / 1 TABLET, FIL... spironolactone Major Pharmaceuticals 2018-08-15
16729-0225-01 100 TABLET, FILM COATED in 1 BOTTLE (16729-225-01) Spironolactone Accord Healthcare, Inc. 2017-06-02
16729-0225-16 500 TABLET, FILM COATED in 1 BOTTLE (16729-225-16) Spironolactone Accord Healthcare, Inc. 2017-06-02
16729-0225-17 1000 TABLET, FILM COATED in 1 BOTTLE (16729-225-17) Spironolactone Accord Healthcare, Inc. 2017-06-15
16729-0226-01 100 TABLET, FILM COATED in 1 BOTTLE (16729-226-01) Spironolactone Accord Healthcare, Inc. 2017-06-02
16729-0226-16 500 TABLET, FILM COATED in 1 BOTTLE (16729-226-16) Spironolactone Accord Healthcare, Inc. 2017-06-02
16729-0227-01 100 TABLET, FILM COATED in 1 BOTTLE (16729-227-01) Spironolactone Accord Healthcare, Inc. 2017-06-02
16729-0227-16 500 TABLET, FILM COATED in 1 BOTTLE (16729-227-16) Spironolactone Accord Healthcare, Inc. 2017-06-02
31722-0094-01 100 TABLET, FILM COATED in 1 BOTTLE (31722-094-01) spironolactone Camber Pharmaceuticals, Inc. 2025-07-25
31722-0094-05 500 TABLET, FILM COATED in 1 BOTTLE (31722-094-05) spironolactone Camber Pharmaceuticals, Inc. 2025-07-25
31722-0094-10 1000 TABLET, FILM COATED in 1 BOTTLE (31722-094-10) spironolactone Camber Pharmaceuticals, Inc. 2025-07-25
31722-0094-30 30 TABLET, FILM COATED in 1 BOTTLE (31722-094-30) spironolactone Camber Pharmaceuticals, Inc. 2025-07-25
31722-0095-01 100 TABLET, FILM COATED in 1 BOTTLE (31722-095-01) spironolactone Camber Pharmaceuticals, Inc. 2025-07-25
31722-0095-05 500 TABLET, FILM COATED in 1 BOTTLE (31722-095-05) spironolactone Camber Pharmaceuticals, Inc. 2025-07-25
31722-0095-10 1000 TABLET, FILM COATED in 1 BOTTLE (31722-095-10) spironolactone Camber Pharmaceuticals, Inc. 2025-07-25
31722-0095-30 30 TABLET, FILM COATED in 1 BOTTLE (31722-095-30) spironolactone Camber Pharmaceuticals, Inc. 2025-07-25
31722-0096-01 100 TABLET, FILM COATED in 1 BOTTLE (31722-096-01) spironolactone Camber Pharmaceuticals, Inc. 2025-07-25
31722-0096-05 500 TABLET, FILM COATED in 1 BOTTLE (31722-096-05) spironolactone Camber Pharmaceuticals, Inc. 2025-07-25
31722-0096-10 1000 TABLET, FILM COATED in 1 BOTTLE (31722-096-10) spironolactone Camber Pharmaceuticals, Inc. 2025-07-25
31722-0096-30 30 TABLET, FILM COATED in 1 BOTTLE (31722-096-30) spironolactone Camber Pharmaceuticals, Inc. 2025-07-25
42708-0101-30 30 TABLET, FILM COATED in 1 BOTTLE (42708-101-30) Spironolactone QPharma, Inc. 2019-10-18
42708-0126-30 30 TABLET in 1 BOTTLE (42708-126-30) Spironolactone QPharma, Inc 2018-05-23
43063-0832-01 100 TABLET, FILM COATED in 1 BOTTLE, PLASTIC (43063-832-01) Spironolactone PD-Rx Pharmaceuticals, Inc. 2018-01-31
43063-0832-30 30 TABLET, FILM COATED in 1 BOTTLE, PLASTIC (43063-832-30) Spironolactone PD-Rx Pharmaceuticals, Inc. 2018-01-31
43063-0832-60 60 TABLET, FILM COATED in 1 BOTTLE, PLASTIC (43063-832-60) Spironolactone PD-Rx Pharmaceuticals, Inc. 2018-06-12
43063-0832-90 90 TABLET, FILM COATED in 1 BOTTLE, PLASTIC (43063-832-90) Spironolactone PD-Rx Pharmaceuticals, Inc. 2018-01-31
48433-0087-20 100 BLISTER PACK in 1 CARTON (48433-087-20) / 1 TABLET, FIL... Spironolactone Safecor Health LLC 2026-05-05
48433-0088-20 100 BLISTER PACK in 1 CARTON (48433-088-20) / 1 TABLET, FIL... Spironolactone Safecor Health LLC 2026-05-05
48433-0089-08 80 BLISTER PACK in 1 CARTON (48433-089-08) / 1 TABLET, FILM... Spironolactone Safecor Health LLC 2026-05-05
50090-0136-00 100 TABLET in 1 BOTTLE, PLASTIC (50090-0136-0) SPIRONOLACTONE A-S Medication Solutions 2014-11-28
50090-0136-01 30 TABLET in 1 BOTTLE, PLASTIC (50090-0136-1) SPIRONOLACTONE A-S Medication Solutions 2014-11-28
50090-0136-06 90 TABLET in 1 BOTTLE, PLASTIC (50090-0136-6) SPIRONOLACTONE A-S Medication Solutions 2014-11-28
50090-3747-00 100 TABLET, FILM COATED in 1 BOTTLE, PLASTIC (50090-3747-0) Spironolactone A-S Medication Solutions 2017-06-02
50090-3747-01 30 TABLET, FILM COATED in 1 BOTTLE (50090-3747-1) Spironolactone A-S Medication Solutions 2018-10-30
50090-3747-06 90 TABLET, FILM COATED in 1 BOTTLE, PLASTIC (50090-3747-6) Spironolactone A-S Medication Solutions 2017-06-02
50090-6369-00 100 TABLET, COATED in 1 BOTTLE (50090-6369-0) Spironolactone A-S Medication Solutions 2023-02-10
50090-6369-01 30 TABLET, COATED in 1 BOTTLE (50090-6369-1) Spironolactone A-S Medication Solutions 2023-02-16
50090-6369-06 90 TABLET, COATED in 1 BOTTLE (50090-6369-6) Spironolactone A-S Medication Solutions 2023-02-16
50090-6908-00 100 TABLET in 1 BOTTLE (50090-6908-0) SPIRONOLACTONE A-S Medication Solutions 2023-12-12
Observed labelers: Bryant Ranch Prepack (48) · Proficient Rx LP (39) · Asclemed USA, Inc. (36) · Amneal Pharmaceuticals LLC (21) · Amneal Pharmaceuticals of New York LLC (18) · Zydus Lifesciences Limited (18) · +28 more — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7
openFDA export observedJul 14, 2026
RxNorm release07/06/2026
Methodology2026-07-full-catalog-v1
  • A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
  • Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
  • Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
  • Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.
This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.