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Lactulose 667 MG/ML Oral Solution — RxCUI 391937

Name: Lactulose 667 MG/ML Oral Solution (RxCUI 391937)
Creator: Brian Staiger, PharmD

RxNorm drug concept · Semantic clinical drug

RxCUI 391937 Semantic clinical drug · SCD ● Current RxNorm concept 25 FDA products 63 package NDCs Snapshot Jul 14, 2026

This page is curated, coded, and maintained by Dr. Brian Staiger, PharmD

Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI391937

Official nameLactulose 667 MG/ML Oral Solution

Concept typeSemantic clinical drug (SCD)

RxNorm statusCurrent RxNorm concept

Also known aslactulose 10 GM per 15 ML Oral Solution; lactulose 10 GM in 15 mL Oral Solution; lactulose 20 GM per 30 ML Oral Solution

FDA products mapped25

Package NDCs mapped63

Reported Medicaid activity (SDUD)800,305 prescriptions · 52 state & territory Medicaid programs · latest period Q4 2025

RxNorm release07/06/2026

Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Lactulose: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist

Lactulose has two main uses. Some products — like Constulose and Kristalose — are prescribed specifically for constipation. Other products, like Enulose and Generlac, are used for...
For constipation, it usually takes 24 to 48 hours to produce a bowel movement, so don't be worried if nothing happens right away. For portal-systemic encephalopathy, improvement ma...
How long does it take lactulose to work?
The most common side effects are digestive — gas, bloating, belching, and mild stomach cramping. These are pretty typical, especially when you first start. The one to watch for is...

📖 Read our full Lactulose guide →

🕸️ Concept Web — How Lactulose 667 MG/ML Oral Solution Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.

This page's concept Lactulose 667 MG/ML Oral Solution RxCUI 391937 Semantic clinical drug · SCD

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

Ingredients 1

The active substance itself — no strength, form, or brand attached yet.
- Lactulose 6218 IN
Brand names 3

The same medicine's trade names. A brand name alone says nothing about strength or form.
- Constulose 216201 BN
- Enulose 216928 BN
- Generlac 217314 BN
Dose forms 15

The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.
- Lactulose Oral Solution 378092 SCDF
- Lactulose Oral Liquid Product 1162200 SCDG
- Lactulose Oral Product 1162201 SCDG
- Lactulose Oral Solution [Constulose] 544451 SBDF
- Lactulose Oral Solution [Enulose] 756967 SBDF
- Lactulose Oral Solution [Generlac] 544454 SBDF
- Constulose Oral Liquid Product 1168758 SBDG
- Constulose Oral Product 1168759 SBDG
- +7 more in this family
Clinical & branded drugs 7

Ingredient + strength + dose form. These are the concepts real FDA products actually carry.
- Lactulose 667 MG/ML 336731 SCDC
- Lactulose 667 MG/ML Oral Solution [Constulose] 544452 SBD
- Lactulose 667 MG/ML Oral Solution [Enulose] 755470 SBD
- Lactulose 667 MG/ML Oral Solution [Generlac] 544455 SBD
- Lactulose 667 MG/ML [Constulose] 544450 SBDC
- Lactulose 667 MG/ML [Enulose] 567837 SBDC
- Lactulose 667 MG/ML [Generlac] 544453 SBDC

Showing up to 8 concepts per family — 19 of 26 stored related concepts drawn.

These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

Lactulose 667 MG/ML SCDC · 336731
Lactulose Oral Solution SCDF · 378092
Lactulose Oral Liquid Product SCDG · 1162200
Lactulose Oral Product SCDG · 1162201

Brand-Name Concepts

Lactulose 667 MG/ML Oral Solution [Constulose] SBD · 544452
Lactulose 667 MG/ML Oral Solution [Enulose] SBD · 755470
Lactulose 667 MG/ML Oral Solution [Generlac] SBD · 544455
Lactulose 667 MG/ML [Constulose] SBDC · 544450
Lactulose 667 MG/ML [Enulose] SBDC · 567837
Lactulose 667 MG/ML [Generlac] SBDC · 544453
Lactulose Oral Solution [Constulose] SBDF · 544451
Lactulose Oral Solution [Enulose] SBDF · 756967
Lactulose Oral Solution [Generlac] SBDF · 544454
Constulose Oral Liquid Product SBDG · 1168758

📦 FDA Products & Package NDCs

25 products · 63 package NDCs

63 package NDCs map to RxCUI 391937 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.

Package NDC	Package	Brand / generic name	Labeler	Marketing start
64980-0592-24	236 mL in 1 BOTTLE (64980-592-24)	Lactulose Solution	Rising Pharma Holdings, Inc.	2023-05-25
64980-0592-48	473 mL in 1 BOTTLE (64980-592-48)	Lactulose Solution	Rising Pharma Holdings, Inc.	2023-05-25
64980-0592-95	946 mL in 1 BOTTLE (64980-592-95)	Lactulose Solution	Rising Pharma Holdings, Inc.	2023-05-25
68999-0002-24	2 TRAY in 1 BOX (68999-002-24) / 10 CUP, UNIT-DOSE in 1 TRA...	Lactulose	Chartwell Governmental & Specialty RX, LLC.	2025-10-29
68999-0004-24	2 TRAY in 1 BOX (68999-004-24) / 10 CUP, UNIT-DOSE in 1 TRA...	Lactulose	Chartwell Governmental & Specialty RX, LLC.	2025-10-29
81033-0241-32	15 mL in 1 BOTTLE, PLASTIC (81033-241-32)	Lactulose Solution	Kesin Pharma Corporation	2025-02-02
82804-0107-47	473 mL in 1 BOTTLE (82804-107-47)	LACTULOSE	Proficient Rx LP	2024-06-14
83745-0249-08	237 mL in 1 BOTTLE (83745-249-08)	Lactulose	APOZEAL PHARMACEUTICALS INC	2024-12-20
83745-0249-16	473 mL in 1 BOTTLE (83745-249-16)	Lactulose	APOZEAL PHARMACEUTICALS INC	2024-12-20
83745-0249-32	946 mL in 1 BOTTLE (83745-249-32)	Lactulose	APOZEAL PHARMACEUTICALS INC	2024-12-20
83745-0405-08	237 mL in 1 BOTTLE (83745-405-08)	Lactulose	APOZEAL PHARMACEUTICALS INC	2024-12-20
83745-0405-16	473 mL in 1 BOTTLE (83745-405-16)	Lactulose	APOZEAL PHARMACEUTICALS INC	2024-12-20
83745-0405-32	946 mL in 1 BOTTLE (83745-405-32)	Lactulose	APOZEAL PHARMACEUTICALS INC	2024-12-20

Observed labelers: PAI Holdings, LLC dba PAI Pharma (10) · Bajaj Medical, LLC (8) · Chartwell RX, LLC (8) · Xttrium Laboratories, Inc. (7) · APOZEAL PHARMACEUTICALS INC (6) · Chartwell RX, LLC. (4) · +11 more — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7

openFDA export observedJul 14, 2026

RxNorm release07/06/2026

Methodology2026-07-full-catalog-v1

A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.

This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.