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Lactulose 667 MG/ML Oral Solution [Constulose] — RxCUI 544452

RxNorm drug concept · Semantic branded drug
RxCUI 544452 Semantic branded drug · SBD ● Current RxNorm concept 1 FDA product 2 package NDCs Snapshot Jul 14, 2026

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Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI544452
Official nameLactulose 667 MG/ML Oral Solution [Constulose]
Concept typeSemantic branded drug (SBD)
RxNorm statusCurrent RxNorm concept
Also known asConstulose 10 GM per 15 ML Syrup; Constulose 10 GM in 15 mL Oral Solution; Constulose 667 MG/ML Oral Solution
FDA products mapped1
Package NDCs mapped2
Reported Medicaid activity (SDUD)115,377 prescriptions · 50 state & territory Medicaid programs · latest period Q4 2025
RxNorm release07/06/2026
Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Lactulose: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist
  • Lactulose has two main uses. Some products — like Constulose and Kristalose — are prescribed specifically for constipation. Other products, like Enulose and Generlac, are used for...
  • For constipation, it usually takes 24 to 48 hours to produce a bowel movement, so don't be worried if nothing happens right away. For portal-systemic encephalopathy, improvement ma...
  • How long does it take lactulose to work?
  • The most common side effects are digestive — gas, bloating, belching, and mild stomach cramping. These are pretty typical, especially when you first start. The one to watch for is...
📖 Read our full Lactulose guide →

🕸️ Concept Web — How Lactulose 667 MG/ML Oral Solution [Constulose] Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.
This page's concept Lactulose 667 MG/ML Oral Solution [Constulose] RxCUI 544452

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

  1. Ingredients 1

    The active substance itself — no strength, form, or brand attached yet.

    • Lactulose 6218
  2. Brand names 1

    The same medicine's trade names. A brand name alone says nothing about strength or form.

    • Constulose 216201
  3. Dose forms 9

    The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.

    • Lactulose Oral Solution 378092
    • Lactulose Oral Liquid Product 1162200
    • Lactulose Oral Product 1162201
    • Lactulose Oral Solution [Constulose] 544451
    • Constulose Oral Liquid Product 1168758
    • Constulose Oral Product 1168759
    • Oral Solution 316968
    • Oral Liquid Product 1151137
    • +1 more in this family
  4. Clinical & branded drugs 3

    Ingredient + strength + dose form. These are the concepts real FDA products actually carry.

Showing up to 8 concepts per family — 13 of 14 stored related concepts drawn.
These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

  • Lactulose 667 MG/ML Oral Solution SCD · 391937
  • Lactulose 667 MG/ML SCDC · 336731
  • Lactulose Oral Solution SCDF · 378092
  • Lactulose Oral Liquid Product SCDG · 1162200
  • Lactulose Oral Product SCDG · 1162201

Brand-Name Concepts

  • Lactulose 667 MG/ML [Constulose] SBDC · 544450
  • Lactulose Oral Solution [Constulose] SBDF · 544451
  • Constulose Oral Liquid Product SBDG · 1168758
  • Constulose Oral Product SBDG · 1168759
  • Constulose BN · 216201

📦 FDA Products & Package NDCs

1 product · 2 package NDCs
2 package NDCs map to RxCUI 544452 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.
Package NDC Package Brand / generic name Labeler Marketing start
45963-0439-63 237 mL in 1 BOTTLE (45963-439-63) Constulose Actavis Pharma, Inc. 2011-02-28
45963-0439-65 946 mL in 1 BOTTLE (45963-439-65) Constulose Actavis Pharma, Inc. 2011-02-28
Observed labelers: Actavis Pharma, Inc. (2) — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

💲 Pricing (NADAC)

NADAC is CMS's National Average Drug Acquisition Cost — roughly what pharmacies pay to buy the drug. It is an acquisition benchmark, not your copay.
Per ml · median
$0.0205
Range $0.0195–$0.0214 · middle 50% $0.0200–$0.0209 · 2 NDCs
Latest compatible distributions from the CMS NADAC file · dataset watermark 2026-07-10. Prices vary by package and pharmacy; a distribution is shown instead of one misleading number. Rows the dataset is silent on carry no price. No zero-cost conclusion should be drawn.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7
openFDA export observedJul 14, 2026
RxNorm release07/06/2026
Methodology2026-07-full-catalog-v1
  • A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
  • Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
  • Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
  • Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.
This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.