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Latanoprost 0.05 MG/ML Ophthalmic Solution [Xalatan] — RxCUI 542527

RxNorm drug concept · Semantic branded drug
RxCUI 542527 Semantic branded drug · SBD ● Current RxNorm concept 1 FDA product 1 package NDC Snapshot Jul 14, 2026

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Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI542527
Official nameLatanoprost 0.05 MG/ML Ophthalmic Solution [Xalatan]
Concept typeSemantic branded drug (SBD)
RxNorm statusCurrent RxNorm concept
Also known asXalatan 0.005 % Ophthalmic Solution; Xalatan 125 MCG per 2.5 ML Ophthalmic Solution; Xalatan 50 MCG/ML Ophthalmic Solution
FDA products mapped1
Package NDCs mapped1
Reported Medicaid activity (SDUD)97 prescriptions · 2 state & territory Medicaid programs · latest period Q4 2025
RxNorm release07/06/2026
Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Latanoprost Ophthalmic: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist
  • The timing matters because latanoprost reaches its maximum pressure-lowering effect about 8 to 12 hours after you put in the drop. Using it in the evening means peak effectiveness...
  • Why does my doctor want me to use these drops in the evening?
  • Yes, this is a known and important effect of latanoprost. It can gradually make the iris — the colored part of your eye — more brown over time, especially if your eyes are a mixed...
  • I noticed my eye color looks different — is that from this medication?
📖 Read our full Latanoprost Ophthalmic guide →

🕸️ Concept Web — How Latanoprost 0.05 MG/ML Ophthalmic Solution [Xala... Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.
This page's concept Latanoprost 0.05 MG/ML Ophthalmic Solution [Xalatan] RxCUI 542527

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

  1. Ingredients 1

    The active substance itself — no strength, form, or brand attached yet.

    • Latanoprost 43611
  2. Brand names 1

    The same medicine's trade names. A brand name alone says nothing about strength or form.

    • Xalatan 153159
  3. Dose forms 6

    The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.

    • Latanoprost Ophthalmic Solution 377441
    • Latanoprost Ophthalmic Product 1162555
    • Latanoprost Ophthalmic Solution [Xalatan] 542526
    • Xalatan Ophthalmic Product 1186297
    • Ophthalmic Solution 7670
    • Ophthalmic Product 1151135
  4. Clinical & branded drugs 3

    Ingredient + strength + dose form. These are the concepts real FDA products actually carry.

Showing up to 8 concepts per family — 11 of 11 stored related concepts drawn.
These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

Brand-Name Concepts

  • Latanoprost 0.05 MG/ML [Xalatan] SBDC · 542525
  • Latanoprost Ophthalmic Solution [Xalatan] SBDF · 542526
  • Xalatan Ophthalmic Product SBDG · 1186297
  • Xalatan BN · 153159

📦 FDA Products & Package NDCs

1 product · 1 package NDC
1 package NDC map to RxCUI 542527 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.
Package NDC Package Brand / generic name Labeler Marketing start
58151-0419-35 1 BOTTLE, DROPPER in 1 CARTON (58151-419-35) / 2.5 mL in 1... XALATAN Viatris Specialty LLC 2024-10-22
Observed labelers: Viatris Specialty LLC (1) — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

💲 Pricing (NADAC)

NADAC is CMS's National Average Drug Acquisition Cost — roughly what pharmacies pay to buy the drug. It is an acquisition benchmark, not your copay.
Per ml · median
$108.3270
Range $108.3270–$108.3270 · middle 50% $108.3270–$108.3270 · 1 NDCs
Latest compatible distributions from the CMS NADAC file · dataset watermark 2026-07-10. Prices vary by package and pharmacy; a distribution is shown instead of one misleading number. Rows the dataset is silent on carry no price. No zero-cost conclusion should be drawn.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7
openFDA export observedJul 14, 2026
RxNorm release07/06/2026
Methodology2026-07-full-catalog-v1
  • A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
  • Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
  • Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
  • Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.
This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.