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Naproxen 375 MG Delayed Release Oral Tablet — RxCUI 603103

RxNorm drug concept · Semantic clinical drug
RxCUI 603103 Semantic clinical drug · SCD ● Current RxNorm concept 14 FDA products 23 package NDCs Snapshot Jul 14, 2026

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Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI603103
Official nameNaproxen 375 MG Delayed Release Oral Tablet
Concept typeSemantic clinical drug (SCD)
RxNorm statusCurrent RxNorm concept
Also known asnaproxen 375 MG (as naproxen sodium 413 MG) Delayed Release Oral Tablet
FDA products mapped14
Package NDCs mapped23
Reported Medicaid activity (SDUD)39,777 prescriptions · 45 state & territory Medicaid programs · latest period Q4 2025
RxNorm release07/06/2026
Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Naproxen: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist
  • They're very similar — naproxen sodium is just the salt form of naproxen, and it dissolves in water more quickly. That means your body absorbs naproxen sodium a bit faster, so it t...
  • What's the difference between naproxen and naproxen sodium — are they the same thing?
  • You can take it either way, but taking it with food, milk, or a full glass of water is a good idea because it helps protect your stomach. Naproxen can irritate the lining of your s...
  • Can I take naproxen on an empty stomach, or do I need to eat first?
📖 Read our full Naproxen guide →

🕸️ Concept Web — How Naproxen 375 MG Delayed Release Oral Tablet Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.
This page's concept Naproxen 375 MG Delayed Release Oral Tablet RxCUI 603103

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

  1. Ingredients 1

    The active substance itself — no strength, form, or brand attached yet.

    • Naproxen 7258
  2. Brand names 1

    The same medicine's trade names. A brand name alone says nothing about strength or form.

    • Naprosyn 203012
  3. Dose forms 9

    The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.

    • Naproxen Delayed Release Oral Tablet 373009
    • Naproxen Oral Product 1157517
    • Naproxen Pill 1157518
    • Naproxen Delayed Release Oral Tablet [Naprosyn] 608792
    • Naprosyn Oral Product 1179304
    • Naprosyn Pill 1179305
    • Delayed Release Oral Tablet 10312
    • Oral Product 1151131
    • +1 more in this family
  4. Clinical & branded drugs 3

    Ingredient + strength + dose form. These are the concepts real FDA products actually carry.

    • Naproxen 375 MG 316327
    • Naproxen 375 MG Delayed Release Oral Tablet [Naprosyn] 608793
    • Naproxen 375 MG [Naprosyn] 564251

Showing up to 8 concepts per family — 13 of 14 stored related concepts drawn.
These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

  • Naproxen 375 MG SCDC · 316327
  • Naproxen Delayed Release Oral Tablet SCDF · 373009
  • Naproxen Oral Product SCDG · 1157517
  • Naproxen Pill SCDG · 1157518

Brand-Name Concepts

  • Naproxen 375 MG Delayed Release Oral Tablet [Naprosyn] SBD · 608793
  • Naproxen 375 MG [Naprosyn] SBDC · 564251
  • Naproxen Delayed Release Oral Tablet [Naprosyn] SBDF · 608792
  • Naprosyn Oral Product SBDG · 1179304
  • Naprosyn Pill SBDG · 1179305
  • Naprosyn BN · 203012

📦 FDA Products & Package NDCs

14 products · 23 package NDCs
23 package NDCs map to RxCUI 603103 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.
Package NDC Package Brand / generic name Labeler Marketing start
11534-0211-01 100 TABLET, DELAYED RELEASE in 1 BOTTLE, PLASTIC (11534-211-... Naproxen Sunrise Pharmaceutical, Inc. 2025-12-09
11534-0212-01 100 TABLET, DELAYED RELEASE in 1 BOTTLE, PLASTIC (11534-212-... Naproxen Sunrise Pharmaceutical, Inc. 2025-12-09
42494-0453-10 100 TABLET in 1 BOTTLE, PLASTIC (42494-453-10) Naproxen Cameron Pharmaceuticals 2023-10-06
42494-0454-10 100 TABLET in 1 BOTTLE, PLASTIC (42494-454-10) Naproxen Cameron Pharmaceuticals 2023-09-26
52817-0380-10 100 TABLET, DELAYED RELEASE in 1 BOTTLE, PLASTIC (52817-380-... Naproxen TruPharma LLC 2023-08-01
52817-0381-10 100 TABLET, DELAYED RELEASE in 1 BOTTLE, PLASTIC (52817-381-... Naproxen TruPharma LLC 2023-08-01
59651-0986-01 100 TABLET, DELAYED RELEASE in 1 BOTTLE (59651-986-01) Naproxen Aurobindo Pharma Limited 2025-05-08
59651-0986-05 500 TABLET, DELAYED RELEASE in 1 BOTTLE (59651-986-05) Naproxen Aurobindo Pharma Limited 2025-05-08
59651-0987-01 100 TABLET, DELAYED RELEASE in 1 BOTTLE (59651-987-01) Naproxen Aurobindo Pharma Limited 2025-05-08
69097-0851-07 100 TABLET, DELAYED RELEASE in 1 BOTTLE (69097-851-07) Naproxen Cipla USA Inc. 2016-07-05
69097-0852-07 100 TABLET, DELAYED RELEASE in 1 BOTTLE (69097-852-07) Naproxen Cipla USA Inc. 2016-07-05
69097-0852-12 500 TABLET, DELAYED RELEASE in 1 BOTTLE (69097-852-12) Naproxen Cipla USA Inc. 2016-07-05
70954-0925-10 100 TABLET, DELAYED RELEASE in 1 BOTTLE (70954-925-10) Naproxen ANI Pharmaceuticals, Inc. 2024-06-13
70954-0928-10 100 TABLET, DELAYED RELEASE in 1 BOTTLE (70954-928-10) Naproxen ANI Pharmaceuticals, Inc. 2024-06-13
71205-0060-14 14 TABLET, DELAYED RELEASE in 1 BOTTLE (71205-060-14) Naproxen Proficient Rx LP 2018-06-01
71205-0060-15 15 TABLET, DELAYED RELEASE in 1 BOTTLE (71205-060-15) Naproxen Proficient Rx LP 2018-06-01
71205-0060-20 20 TABLET, DELAYED RELEASE in 1 BOTTLE (71205-060-20) Naproxen Proficient Rx LP 2018-06-01
71205-0060-30 30 TABLET, DELAYED RELEASE in 1 BOTTLE (71205-060-30) Naproxen Proficient Rx LP 2018-06-01
71205-0060-40 40 TABLET, DELAYED RELEASE in 1 BOTTLE (71205-060-40) Naproxen Proficient Rx LP 2018-06-01
71205-0060-45 45 TABLET, DELAYED RELEASE in 1 BOTTLE (71205-060-45) Naproxen Proficient Rx LP 2018-06-01
71205-0060-60 60 TABLET, DELAYED RELEASE in 1 BOTTLE (71205-060-60) Naproxen Proficient Rx LP 2018-06-01
71205-0060-90 90 TABLET, DELAYED RELEASE in 1 BOTTLE (71205-060-90) Naproxen Proficient Rx LP 2018-06-01
72162-2275-01 100 TABLET in 1 BOTTLE (72162-2275-1) Naproxen Bryant Ranch Prepack 2024-04-30
Observed labelers: Proficient Rx LP (8) · Aurobindo Pharma Limited (3) · Cipla USA Inc. (3) · ANI Pharmaceuticals, Inc. (2) · Cameron Pharmaceuticals (2) · Sunrise Pharmaceutical, Inc. (2) · +2 more — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7
openFDA export observedJul 14, 2026
RxNorm release07/06/2026
Methodology2026-07-full-catalog-v1
  • A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
  • Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
  • Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
  • Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.
This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.