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Naproxen sodium 500 MG / sumatriptan 85 MG Oral Tablet — RxCUI 849450

Name: Naproxen sodium 500 MG / sumatriptan 85 MG Oral Tablet (RxCUI 849450)
Creator: Brian Staiger, PharmD

RxNorm drug concept · Semantic clinical drug

RxCUI 849450 Semantic clinical drug · SCD ● Current RxNorm concept 5 FDA products 7 package NDCs Snapshot Jul 14, 2026

This page is curated, coded, and maintained by Dr. Brian Staiger, PharmD

Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI849450

Official nameNaproxen sodium 500 MG / sumatriptan 85 MG Oral Tablet

Concept typeSemantic clinical drug (SCD)

RxNorm statusCurrent RxNorm concept

Also known asnaproxen sodium 500 MG / sumatriptan (as sumatriptan succinate) 85 MG Oral Tablet

FDA products mapped5

Package NDCs mapped7

Reported Medicaid activity (SDUD)467 prescriptions · 5 state & territory Medicaid programs · latest period Q4 2025

RxNorm release07/06/2026

Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Sumatriptan: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist

Sumatriptan is specifically for migraine headaches — it's not a general pain reliever like ibuprofen. It's designed to stop a migraine attack once it's already started, with or wit...
What exactly is sumatriptan for? Will it work on any headache?
You don't need to wait until it's unbearable. Taking sumatriptan at the first sign of a migraine is generally the right move — don't wait it out. That said, it is meant for confirm...
When should I take sumatriptan — do I have to wait until the headache is severe?

📖 Read our full Sumatriptan guide →

🕸️ Concept Web — How Naproxen sodium 500 MG / sumatriptan 85 MG Oral... Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.

This page's concept Naproxen sodium 500 MG / sumatriptan 85 MG Oral Tablet RxCUI 849450 Semantic clinical drug · SCD

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

Ingredients 4

The active substance itself — no strength, form, or brand attached yet.
- Naproxen 7258 IN
- Sumatriptan 37418 IN
- Naproxen / sumatriptan 797426 MIN
- Naproxen sodium 142442 PIN
Brand names 1

The same medicine's trade names. A brand name alone says nothing about strength or form.
- Treximet 794765 BN
Dose forms 13

The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.
- Naproxen / sumatriptan Oral Tablet 794763 SCDF
- Naproxen sodium / sumatriptan Oral Tablet 2647518 SCDFP
- Naproxen / sumatriptan Oral Product 1157005 SCDG
- Naproxen / sumatriptan Pill 1157512 SCDG
- Naproxen sodium / sumatriptan Oral Product 2661109 SCDGP
- Naproxen sodium / sumatriptan Pill 2661991 SCDGP
- Naproxen / sumatriptan Oral Tablet [Treximet] 794767 SBDF
- Naproxen sodium / sumatriptan Oral Tablet [Treximet] 2654512 SBDFP
- +5 more in this family
Clinical & branded drugs 4

Ingredient + strength + dose form. These are the concepts real FDA products actually carry.
- Naproxen sodium 500 MG 849449 SCDC
- Sumatriptan 85 MG 644919 SCDC
- Naproxen sodium 500 MG / sumatriptan 85 MG Oral Tablet [Treximet] 849452 SBD
- Naproxen sodium 500 MG / sumatriptan 85 MG [Treximet] 849451 SBDC

Showing up to 8 concepts per family — 17 of 22 stored related concepts drawn.

These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

Naproxen sodium 500 MG SCDC · 849449
Sumatriptan 85 MG SCDC · 644919
Naproxen / sumatriptan Oral Tablet SCDF · 794763
Naproxen sodium / sumatriptan Oral Tablet SCDFP · 2647518
Naproxen / sumatriptan Oral Product SCDG · 1157005
Naproxen / sumatriptan Pill SCDG · 1157512
Naproxen sodium / sumatriptan Oral Product SCDGP · 2661109
Naproxen sodium / sumatriptan Pill SCDGP · 2661991

Brand-Name Concepts

Naproxen sodium 500 MG / sumatriptan 85 MG Oral Tablet [Treximet] SBD · 849452
Naproxen sodium 500 MG / sumatriptan 85 MG [Treximet] SBDC · 849451
Naproxen / sumatriptan Oral Tablet [Treximet] SBDF · 794767
Naproxen sodium / sumatriptan Oral Tablet [Treximet] SBDFP · 2654512
Treximet Oral Product SBDG · 1179685
Treximet Pill SBDG · 1179686
Treximet BN · 794765

📦 FDA Products & Package NDCs

5 products · 7 package NDCs

7 package NDCs map to RxCUI 849450 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.

Package NDC	Package	Brand / generic name	Labeler	Marketing start
16714-0891-01	9 TABLET, FILM COATED in 1 BOTTLE (16714-891-01)	Sumatriptan and Naproxen Sodium	NorthStar RxLLC	2018-11-27
42847-0850-09	9 TABLET, FILM COATED in 1 BOTTLE (42847-850-09)	Treximet	Currax Pharmaceuticals LLC	2008-04-25
44183-0850-09	9 TABLET in 1 BOTTLE (44183-850-09)	Sumatriptan Succinate and Naproxen Sodium	Currax Pharmaceuticals LLC dba Cypress, Hawthorn, Macoven	2018-02-15
47335-0410-22	9 TABLET, FILM COATED in 1 BOTTLE (47335-410-22)	Sumatriptan and Naproxen Sodium	Sun Pharmaceutical Industries, Inc.	2018-07-20
47335-0410-83	30 TABLET, FILM COATED in 1 BOTTLE (47335-410-83)	Sumatriptan and Naproxen Sodium	Sun Pharmaceutical Industries, Inc.	2018-07-20
47335-0410-88	100 TABLET, FILM COATED in 1 BOTTLE (47335-410-88)	Sumatriptan and Naproxen Sodium	Sun Pharmaceutical Industries, Inc.	2018-07-20
65862-0928-36	9 TABLET, FILM COATED in 1 BOTTLE (65862-928-36)	Sumatriptan and Naproxen Sodium	Aurobindo Pharma Limited	2018-02-15

Observed labelers: Sun Pharmaceutical Industries, Inc. (3) · Aurobindo Pharma Limited (1) · Currax Pharmaceuticals LLC (1) · Currax Pharmaceuticals LLC dba Cypress, Hawthorn, Macoven (1) · NorthStar RxLLC (1) — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7

openFDA export observedJul 14, 2026

RxNorm release07/06/2026

Methodology2026-07-full-catalog-v1

A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.

This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.