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Acetaminophen 300 MG / butalbital 50 MG / caffeine 40 MG Oral Capsule — RxCUI 889520

RxNorm drug concept · Semantic clinical drug
RxCUI 889520 Semantic clinical drug · SCD ● Current RxNorm concept 16 FDA products 20 package NDCs Snapshot Jul 14, 2026

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Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI889520
Official nameAcetaminophen 300 MG / butalbital 50 MG / caffeine 40 MG Oral Capsule
Concept typeSemantic clinical drug (SCD)
RxNorm statusCurrent RxNorm concept
Also known asAPAP 300 MG / butalbital 50 MG / caffeine 40 MG Oral Capsule
FDA products mapped16
Package NDCs mapped20
Reported Medicaid activity (SDUD)50,211 prescriptions · 41 state & territory Medicaid programs · latest period Q4 2025
RxNorm release07/06/2026
Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Acetaminophen, Butalbital, and Caffeine: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist
  • Yes, that's exactly what it's intended for. This combination of butalbital, acetaminophen, and caffeine is prescribed specifically to relieve tension headaches — the kind caused by...
  • What exactly is this medication for? My doctor prescribed it for headaches — is that normal?
  • This is actually something to be careful about. Butalbital, one of the ingredients, is habit-forming — meaning your body can become physically dependent on it if you take it freque...
  • Can I take this regularly if I get headaches a lot?
📖 Read our full Acetaminophen, Butalbital, and Caffeine guide →

🕸️ Concept Web — How Acetaminophen 300 MG / butalbital 50 MG / caffei... Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.
This page's concept Acetaminophen 300 MG / butalbital 50 MG / caffeine 40 MG Oral Capsule RxCUI 889520

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

  1. Ingredients 4

    The active substance itself — no strength, form, or brand attached yet.

    • Acetaminophen 161
    • Butalbital 19860
    • Caffeine 1886
    • Acetaminophen / butalbital / caffeine 214130
  2. Brand names 1

    The same medicine's trade names. A brand name alone says nothing about strength or form.

    • Fioricet 175184
  3. Dose forms 9

    The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.

    • Acetaminophen / butalbital / caffeine Oral Capsule 374750
    • Acetaminophen / butalbital / caffeine Oral Product 1152255
    • Acetaminophen / butalbital / caffeine Pill 1152256
    • Acetaminophen / butalbital / caffeine Oral Capsule [Fioricet] 1432260
    • Fioricet Oral Product 1168322
    • Fioricet Pill 1168323
    • Oral Capsule 316965
    • Oral Product 1151131
    • +1 more in this family
  4. Clinical & branded drugs 5

    Ingredient + strength + dose form. These are the concepts real FDA products actually carry.

Showing up to 8 concepts per family — 18 of 19 stored related concepts drawn.
These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

  • Acetaminophen 300 MG SCDC · 315261
  • Butalbital 50 MG SCDC · 317309
  • Caffeine 40 MG SCDC · 317310
  • Acetaminophen / butalbital / caffeine Oral Capsule SCDF · 374750
  • Acetaminophen / butalbital / caffeine Oral Product SCDG · 1152255
  • Acetaminophen / butalbital / caffeine Pill SCDG · 1152256

Brand-Name Concepts

📦 FDA Products & Package NDCs

16 products · 20 package NDCs
20 package NDCs map to RxCUI 889520 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.
Package NDC Package Brand / generic name Labeler Marketing start
00527-4095-37 100 CAPSULE in 1 BOTTLE (0527-4095-37) Butalbital, Acetaminophen, and Caffeine Lannett Company, Inc. 2019-12-17
00591-2640-01 100 CAPSULE in 1 BOTTLE (0591-2640-01) Butalbital, Acetaminophen, and Caffeine Actavis Pharma, Inc. 2013-07-29
00591-2640-05 500 CAPSULE in 1 BOTTLE (0591-2640-05) Butalbital, Acetaminophen, and Caffeine Actavis Pharma, Inc. 2013-07-29
11534-0187-01 100 CAPSULE in 1 BOTTLE (11534-187-01) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE SUNRISE PHARMACEUTICAL, INC 2017-01-10
11534-0187-04 500 CAPSULE in 1 BOTTLE (11534-187-04) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE SUNRISE PHARMACEUTICAL, INC 2017-01-10
13925-0535-01 100 CAPSULE in 1 BOTTLE (13925-535-01) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE Seton Pharmaceuticals LLC 2022-03-02
13925-0536-01 100 CAPSULE in 1 BOTTLE (13925-536-01) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE Seton Pharmaceuticals LLC 2022-03-02
16714-0170-01 100 CAPSULE in 1 BOTTLE (16714-170-01) Butalbital, Acetaminophen, and Caffeine NORTHSTAR RX LLC 2020-09-23
42291-0181-01 100 CAPSULE in 1 BOTTLE (42291-181-01) Butalbital, Acetaminophen, and Caffeine AvKARE 2014-11-24
43547-0686-10 100 CAPSULE in 1 BOTTLE (43547-686-10) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE SOLCO HEALTHCARE US, LLC 2023-12-05
51672-4222-01 100 CAPSULE in 1 BOTTLE (51672-4222-1) Butalbital, Acetaminophen and Caffeine Taro Pharmaceuticals U.S.A., Inc. 2020-07-01
52544-0080-01 100 CAPSULE in 1 BOTTLE (52544-080-01) Fioricet Actavis Pharma, Inc. 2013-07-29
63629-2372-01 100 CAPSULE in 1 BOTTLE (63629-2372-1) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE Bryant Ranch Prepack 2021-02-22
70010-0044-01 100 CAPSULE in 1 BOTTLE (70010-044-01) Butalbital, Acetaminophen and Caffeine Granules Pharmaceuticals Inc. 2020-05-05
70010-0044-05 500 CAPSULE in 1 BOTTLE (70010-044-05) Butalbital, Acetaminophen and Caffeine Granules Pharmaceuticals Inc. 2020-05-05
70752-0144-10 100 CAPSULE in 1 BOTTLE, PLASTIC (70752-144-10) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE QUAGEN PHARMACEUTICALS LLC 2024-05-01
70752-0144-14 500 CAPSULE in 1 BOTTLE, PLASTIC (70752-144-14) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE QUAGEN PHARMACEUTICALS LLC 2024-05-01
72162-1232-01 100 CAPSULE in 1 BOTTLE (72162-1232-1) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE Bryant Ranch Prepack 2023-10-02
80425-0215-01 30 CAPSULE in 1 BOTTLE (80425-0215-1) Butalbital/Acetaminophen/Caffeine Advanced Rx Pharmacy of Tennessee, LLC 2023-01-03
80425-0497-01 30 CAPSULE in 1 BOTTLE (80425-0497-1) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE Advanced Rx of Tennessee, LLC 2025-02-14
Observed labelers: Actavis Pharma, Inc. (3) · Bryant Ranch Prepack (2) · Granules Pharmaceuticals Inc. (2) · QUAGEN PHARMACEUTICALS LLC (2) · Seton Pharmaceuticals LLC (2) · SUNRISE PHARMACEUTICAL, INC (2) · +7 more — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7
openFDA export observedJul 14, 2026
RxNorm release07/06/2026
Methodology2026-07-full-catalog-v1
  • A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
  • Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
  • Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
  • Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.
This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.