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Promethazine hydrochloride 1.25 MG/ML Oral Solution — RxCUI 992432

Name: Promethazine hydrochloride 1.25 MG/ML Oral Solution (RxCUI 992432)
Creator: Brian Staiger, PharmD

RxNorm drug concept · Semantic clinical drug

RxCUI 992432 Semantic clinical drug · SCD ● Current RxNorm concept 13 FDA products 18 package NDCs Snapshot Jul 14, 2026

This page is curated, coded, and maintained by Dr. Brian Staiger, PharmD

Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI992432

Official namePromethazine hydrochloride 1.25 MG/ML Oral Solution

Concept typeSemantic clinical drug (SCD)

RxNorm statusCurrent RxNorm concept

Also known aspromethazine HCl 6.25 MG per 5 ML Oral Syrup; promethazine HCl 6.25 MG in 5 mL Oral Solution

FDA products mapped13

Package NDCs mapped18

Reported Medicaid activity (SDUD)236,130 prescriptions · 47 state & territory Medicaid programs · latest period Q4 2025

RxNorm release07/06/2026

Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Promethazine: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist

It treats allergy symptoms like allergic rhinitis and hives, motion sickness, and nausea and vomiting around surgery. It is also used for sedation. Which uses apply depends on the...
Very likely. Drowsiness is its most common effect. Don't drive or use machinery until you know how it affects you, and avoid alcohol and other sedating medicines.
Not if the child is under 2. It can cause fatal slowed breathing in that age group. For children 2 and older, it needs real caution and the lowest effective dose, so only use it as...
Use an accurate measuring device, not a kitchen teaspoon, which can lead to overdose. I can give you an oral syringe or dosing cup and show you how to measure.

📖 Read our full Promethazine guide →

🕸️ Concept Web — How Promethazine hydrochloride 1.25 MG/ML Oral Solut... Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.

This page's concept Promethazine hydrochloride 1.25 MG/ML Oral Solution RxCUI 992432 Semantic clinical drug · SCD

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

Ingredients 2

The active substance itself — no strength, form, or brand attached yet.
- Promethazine 8745 IN
- Promethazine hydrochloride 142445 PIN
Dose forms 9

The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.
- Promethazine Oral Solution 450999 SCDF
- Promethazine hydrochloride Oral Solution 2648816 SCDFP
- Promethazine Oral Liquid Product 1162311 SCDG
- Promethazine Oral Product 1162312 SCDG
- Promethazine hydrochloride Oral Liquid Product 2661709 SCDGP
- Promethazine hydrochloride Oral Product 2660458 SCDGP
- Oral Solution 316968 DF
- Oral Liquid Product 1151137 DFG
- +1 more in this family
Clinical & branded drugs 1

Ingredient + strength + dose form. These are the concepts real FDA products actually carry.
- Promethazine hydrochloride 1.25 MG/ML 991457 SCDC

Showing up to 8 concepts per family — 11 of 12 stored related concepts drawn.

These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

Promethazine hydrochloride 1.25 MG/ML SCDC · 991457
Promethazine Oral Solution SCDF · 450999
Promethazine hydrochloride Oral Solution SCDFP · 2648816
Promethazine Oral Liquid Product SCDG · 1162311
Promethazine Oral Product SCDG · 1162312
Promethazine hydrochloride Oral Liquid Product SCDGP · 2661709
Promethazine hydrochloride Oral Product SCDGP · 2660458

📦 FDA Products & Package NDCs

13 products · 18 package NDCs

18 package NDCs map to RxCUI 992432 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.

Package NDC	Package	Brand / generic name	Labeler	Marketing start
00116-4023-16	473 mL in 1 BOTTLE, PLASTIC (0116-4023-16)	PROMETHAZINE HYDROCHLORIDE	Xttrium Laboratories, Inc.	2025-04-07
00121-1854-16	473 mL in 1 BOTTLE (0121-1854-16)	Promethazine Hydrochloride	PAI Holdings, LLC dba PAI Pharma	2025-08-07
17856-0059-01	72 CUP, UNIT-DOSE in 1 BOX, UNIT-DOSE (17856-0059-1) / 5 mL...	promethazine hydrochloride	ATLANTIC BIOLOGICALS CORP	2023-11-13
17856-4023-01	72 CUP, UNIT-DOSE in 1 CASE (17856-4023-1) / 5 mL in 1 CUP,...	PROMETHAZINE HYDROCHLORIDE	Atlantic Biologicals Corp.	2026-04-20
27808-0051-02	473 mL in 1 BOTTLE (27808-051-02)	promethazine hydrochloride	Cranbury Pharmaceuticals, LLC	2021-09-30
29033-0500-34	473 mL in 1 BOTTLE (29033-500-34)	PROMETHAZINE HYDROCHLORIDE	Nostrum Laboratories, Inc.	2024-07-18
50090-6431-00	473 mL in 1 BOTTLE (50090-6431-0)	promethazine hydrochloride	A-S Medication Solutions	2023-04-10
62135-0774-23	2 TRAY in 1 BOX (62135-774-23) / 10 CUP in 1 TRAY / 10 mL i...	PROMETHAZINE HYDROCHLORIDE	Chartwell RX, LLC	2025-02-10
62135-0774-24	2 TRAY in 1 BOX (62135-774-24) / 10 CUP in 1 TRAY / 5 mL in...	PROMETHAZINE HYDROCHLORIDE	Chartwell RX, LLC	2025-02-10
62135-0774-41	120 mL in 1 BOTTLE (62135-774-41)	PROMETHAZINE HYDROCHLORIDE	Chartwell RX, LLC	2023-11-27
62135-0774-47	473 mL in 1 BOTTLE (62135-774-47)	PROMETHAZINE HYDROCHLORIDE	Chartwell RX, LLC	2023-11-27
68999-0774-23	2 TRAY in 1 BOX (68999-774-23) / 10 CUP in 1 TRAY / 10 mL i...	PROMETHAZINE HYDROCHLORIDE	Chartwell Governmental & Specialty RX, LLC.	2025-11-20
68999-0774-24	2 TRAY in 1 BOX (68999-774-24) / 10 CUP in 1 TRAY / 5 mL in...	PROMETHAZINE HYDROCHLORIDE	Chartwell Governmental & Specialty RX, LLC.	2025-11-20
70752-0138-06	118 mL in 1 BOTTLE, PLASTIC (70752-138-06)	Promethazine Hydrochloride	QUAGEN PHARMACEUTICALS LLC	2021-07-12
70752-0138-12	473 mL in 1 BOTTLE, PLASTIC (70752-138-12)	Promethazine Hydrochloride	QUAGEN PHARMACEUTICALS LLC	2021-07-12
72162-2071-02	473 mL in 1 BOTTLE (72162-2071-2)	Promethazine Hydrochloride	Bryant Ranch Prepack	2023-08-15
72162-2377-02	473 mL in 1 BOTTLE (72162-2377-2)	PROMETHAZINE HYDROCHLORIDE	Bryant Ranch Prepack	2024-07-30
81033-0016-50	50 CUP, UNIT-DOSE in 1 CARTON (81033-016-50) / 5 mL in 1 CU...	PROMETHAZINE HYDROCHLORIDE	Kesin Pharma Corporation	2024-12-31

Observed labelers: Chartwell RX, LLC (4) · Bryant Ranch Prepack (2) · Chartwell Governmental & Specialty RX, LLC. (2) · QUAGEN PHARMACEUTICALS LLC (2) · A-S Medication Solutions (1) · ATLANTIC BIOLOGICALS CORP (1) · +6 more — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7

openFDA export observedJul 14, 2026

RxNorm release07/06/2026

Methodology2026-07-full-catalog-v1

A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.

This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.