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Promethazine hydrochloride 12.5 MG Rectal Suppository — RxCUI 992441

RxNorm drug concept · Semantic clinical drug
RxCUI 992441 Semantic clinical drug · SCD ● Current RxNorm concept 9 FDA products 12 package NDCs Snapshot Jul 14, 2026

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Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI992441
Official namePromethazine hydrochloride 12.5 MG Rectal Suppository
Concept typeSemantic clinical drug (SCD)
RxNorm statusCurrent RxNorm concept
Also known aspromethazine HCl 12.5 MG Rectal Suppository
FDA products mapped9
Package NDCs mapped12
Reported Medicaid activity (SDUD)64,981 prescriptions · 47 state & territory Medicaid programs · latest period Q4 2025
RxNorm release07/06/2026
Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Promethazine: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist
  • It treats allergy symptoms like allergic rhinitis and hives, motion sickness, and nausea and vomiting around surgery. It is also used for sedation. Which uses apply depends on the...
  • Very likely. Drowsiness is its most common effect. Don't drive or use machinery until you know how it affects you, and avoid alcohol and other sedating medicines.
  • Not if the child is under 2. It can cause fatal slowed breathing in that age group. For children 2 and older, it needs real caution and the lowest effective dose, so only use it as...
  • Use an accurate measuring device, not a kitchen teaspoon, which can lead to overdose. I can give you an oral syringe or dosing cup and show you how to measure.
📖 Read our full Promethazine guide →

🕸️ Concept Web — How Promethazine hydrochloride 12.5 MG Rectal Suppos... Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.
This page's concept Promethazine hydrochloride 12.5 MG Rectal Suppository RxCUI 992441

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

  1. Ingredients 2

    The active substance itself — no strength, form, or brand attached yet.

    • Promethazine 8745
    • Promethazine hydrochloride 142445
  2. Brand names 2

    The same medicine's trade names. A brand name alone says nothing about strength or form.

    • Phenergan 152218
    • Promethegan 219442
  3. Dose forms 12

    The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.

    • Promethazine Rectal Suppository 373632
    • Promethazine hydrochloride Rectal Suppository 2648801
    • Promethazine Rectal Product 1162314
    • Promethazine hydrochloride Rectal Product 2663469
    • Promethazine Rectal Suppository [Phenergan] 367532
    • Promethazine Rectal Suppository [Promethegan] 367515
    • Promethazine hydrochloride Rectal Suppository [Phenergan] 2656141
    • Promethazine hydrochloride Rectal Suppository [Promethegan] 2654892
    • +4 more in this family
  4. Clinical & branded drugs 5

    Ingredient + strength + dose form. These are the concepts real FDA products actually carry.

Showing up to 8 concepts per family — 17 of 21 stored related concepts drawn.
These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

  • Promethazine hydrochloride 12.5 MG SCDC · 992437
  • Promethazine Rectal Suppository SCDF · 373632
  • Promethazine hydrochloride Rectal Suppository SCDFP · 2648801
  • Promethazine Rectal Product SCDG · 1162314
  • Promethazine hydrochloride Rectal Product SCDGP · 2663469

Brand-Name Concepts

  • Promethazine hydrochloride 12.5 MG Rectal Suppository [Promethegan] SBD · 992445
  • Promethazine hydrochloride 12.5 MG Rectal Suppository [Phenergan] SBD · 992446
  • Promethazine hydrochloride 12.5 MG [Phenergan] SBDC · 992439
  • Promethazine hydrochloride 12.5 MG [Promethegan] SBDC · 992444
  • Promethazine Rectal Suppository [Phenergan] SBDF · 367532
  • Promethazine Rectal Suppository [Promethegan] SBDF · 367515
  • Promethazine hydrochloride Rectal Suppository [Phenergan] SBDFP · 2656141
  • Promethazine hydrochloride Rectal Suppository [Promethegan] SBDFP · 2654892
  • Phenergan Rectal Product SBDG · 1179489
  • Promethegan Rectal Product SBDG · 1181290

📦 FDA Products & Package NDCs

9 products · 12 package NDCs
12 package NDCs map to RxCUI 992441 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.
Package NDC Package Brand / generic name Labeler Marketing start
00713-0526-10 1000 SUPPOSITORY in 1 BOX (0713-0526-10) PROMETHEGAN Cosette Pharmaceuticals, Inc. 2002-02-28
00713-0526-12 12 SUPPOSITORY in 1 BOX (0713-0526-12) PROMETHEGAN Cosette Pharmaceuticals, Inc. 2002-02-28
00713-0536-10 1000 SUPPOSITORY in 1 BOX (0713-0536-10) PROMETHEGAN Cosette Pharmaceuticals, Inc. 2004-02-28
00713-0536-12 12 SUPPOSITORY in 1 BOX (0713-0536-12) PROMETHEGAN Cosette Pharmaceuticals, Inc. 2004-02-28
31722-0040-31 2 BLISTER PACK in 1 CARTON (31722-040-31) / 6 SUPPOSITORY i... Promethazine Hydrochloride Camber Pharmaceuticals, Inc. 2022-11-02
31722-0041-31 2 BLISTER PACK in 1 CARTON (31722-041-31) / 6 SUPPOSITORY i... Promethazine Hydrochloride Camber Pharmaceuticals, Inc. 2022-11-02
45802-0758-30 12 BLISTER PACK in 1 CARTON (45802-758-30) / 1 SUPPOSITORY... Promethazine Hydrochloride Padagis Israel Pharmaceuticals Ltd 2006-06-27
45802-0759-30 12 BLISTER PACK in 1 CARTON (45802-759-30) / 1 SUPPOSITORY... Promethazine Hydrochloride Padagis Israel Pharmaceuticals Ltd 2006-05-17
50090-2747-01 4 BLISTER PACK in 1 CARTON (50090-2747-1) / 1 SUPPOSITORY i... Promethazine Hydrochloride A-S Medication Solutions 2017-01-05
50090-2747-02 6 BLISTER PACK in 1 CARTON (50090-2747-2) / 1 SUPPOSITORY i... Promethazine Hydrochloride A-S Medication Solutions 2017-01-11
76420-0388-30 12 BLISTER PACK in 1 CARTON (76420-388-30) / 1 SUPPOSITORY... Promethazine Hydrochloride Asclemed USA, Inc. 2025-06-07
76420-0389-30 12 BLISTER PACK in 1 CARTON (76420-389-30) / 1 SUPPOSITORY... Promethazine Hydrochloride Asclemed USA, Inc. 2025-06-07
Observed labelers: Cosette Pharmaceuticals, Inc. (4) · A-S Medication Solutions (2) · Asclemed USA, Inc. (2) · Camber Pharmaceuticals, Inc. (2) · Padagis Israel Pharmaceuticals Ltd (2) — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7
openFDA export observedJul 14, 2026
RxNorm release07/06/2026
Methodology2026-07-full-catalog-v1
  • A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
  • Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
  • Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
  • Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.
This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.