12 HR orphenadrine citrate 100 MG Extended Release Oral Tablet — RxCUI 994521
RxNorm drug concept · Semantic clinical drug
RxCUI 994521
Semantic clinical drug · SCD
● Current RxNorm concept 17 FDA products
51 package NDCs
Snapshot Jul 14, 2026
What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.
🗂️ Key Facts
RxCUI994521
Official name12 HR orphenadrine citrate 100 MG Extended Release Oral Tablet
Concept typeSemantic clinical drug (SCD)
RxNorm statusCurrent RxNorm concept
Also known asorphenadrine citrate 100 MG 12HR Extended Release Oral Tablet
FDA products mapped17
Package NDCs mapped51
Reported Medicaid activity (SDUD)66,639 prescriptions · 44 state & territory Medicaid programs · latest period Q4 2025
RxNorm release07/06/2026
Snapshot dataJul 14, 2026
📖 Skip the Codes — Read It in Plain English.
Our pharmacist-built guide to Orphenadrine: what it is, how it’s used, side effects, and interactions.
📗 Our plain-language guide HelloPharmacist
- It's a common assumption, but orphenadrine actually doesn't directly relax tense muscles. Researchers believe its benefit comes from pain-relieving properties — so it helps you fee...
- What exactly does orphenadrine do — does it just relax my muscles?
- Take one extended-release tablet in the morning and one in the evening — that's twice a day. Try to stick to the same times each day. If you're unsure whether to take it with food...
- How should I take the extended-release tablet?
🕸️ Concept Web — How 12 HR orphenadrine citrate 100 MG Extended Relea... Connects
One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.
This page's concept
12 HR orphenadrine citrate 100 MG Extended Release Oral Tablet
RxCUI 994521 Semantic clinical drug · SCD
Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.
-
Ingredients 2
The active substance itself — no strength, form, or brand attached yet.
-
Orphenadrine
7715IN -
Orphenadrine citrate
7716PIN
-
Orphenadrine
-
Dose forms 9
The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.
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Orphenadrine Extended Release Oral Tablet
373158SCDF -
Orphenadrine citrate Extended Release Oral Tablet
2646635SCDFP -
Orphenadrine Oral Product
1161644SCDG -
Orphenadrine Pill
1161645SCDG -
Orphenadrine citrate Oral Product
2661499SCDGP -
Orphenadrine citrate Pill
2660974SCDGP -
Extended Release Oral Tablet
316945DF -
Oral Product
1151131DFG - +1 more in this family
-
Orphenadrine Extended Release Oral Tablet
-
Clinical & branded drugs 1
Ingredient + strength + dose form. These are the concepts real FDA products actually carry.
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Orphenadrine citrate 100 MG
994520SCDC
-
Orphenadrine citrate 100 MG
Showing up to 8 concepts per family — 11 of 12 stored related concepts drawn.
These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.
🔀 Generic ⇄ Brand Crosswalk
The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.
Generic (Clinical) Concepts
-
Orphenadrine citrate 100 MG
SCDC · 994520 -
Orphenadrine Extended Release Oral Tablet
SCDF · 373158 -
Orphenadrine citrate Extended Release Oral Tablet
SCDFP · 2646635 -
Orphenadrine Oral Product
SCDG · 1161644 -
Orphenadrine Pill
SCDG · 1161645 -
Orphenadrine citrate Oral Product
SCDGP · 2661499 -
Orphenadrine citrate Pill
SCDGP · 2660974
📦 FDA Products & Package NDCs
17 products · 51 package NDCs
51 package NDCs map to RxCUI 994521 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.
| Package NDC | Package | Brand / generic name | Labeler | Marketing start |
|---|---|---|---|---|
| 00185-0022-01 | 100 TABLET, EXTENDED RELEASE in 1 BOTTLE (0185-0022-01) | Orphenadrine Citrate | Sandoz Inc | 2000-02-15 |
| 43063-0407-14 | 14 TABLET, EXTENDED RELEASE in 1 BOTTLE, PLASTIC (43063-407-... | ORPHENADRINE CITRATE | PD-Rx Pharmaceuticals, Inc. | 2013-06-18 |
| 43063-0407-20 | 20 TABLET, EXTENDED RELEASE in 1 BOTTLE, PLASTIC (43063-407-... | ORPHENADRINE CITRATE | PD-Rx Pharmaceuticals, Inc. | 2013-06-18 |
| 43063-0407-30 | 30 TABLET, EXTENDED RELEASE in 1 BOTTLE, PLASTIC (43063-407-... | ORPHENADRINE CITRATE | PD-Rx Pharmaceuticals, Inc. | 2013-06-18 |
| 43063-0407-60 | 60 TABLET, EXTENDED RELEASE in 1 BOTTLE, PLASTIC (43063-407-... | ORPHENADRINE CITRATE | PD-Rx Pharmaceuticals, Inc. | 2013-06-18 |
| 43386-0480-24 | 100 TABLET, EXTENDED RELEASE in 1 BOTTLE (43386-480-24) | ORPHENADRINE CITRATE | Lupin Pharmaceuticals, Inc. | 1998-06-19 |
| 43386-0480-26 | 500 TABLET, EXTENDED RELEASE in 1 BOTTLE (43386-480-26) | ORPHENADRINE CITRATE | Lupin Pharmaceuticals, Inc. | 1998-06-19 |
| 43386-0480-28 | 1000 TABLET, EXTENDED RELEASE in 1 BOTTLE (43386-480-28) | ORPHENADRINE CITRATE | Lupin Pharmaceuticals, Inc. | 1998-06-19 |
| 49999-0046-60 | 60 TABLET, EXTENDED RELEASE in 1 BOTTLE, PLASTIC (49999-046-... | Orphenadrine Citrate | Lake Erie Medical DBA Quality Care Products LLC | 2011-02-07 |
| 50090-0169-00 | 20 TABLET, EXTENDED RELEASE in 1 BOTTLE (50090-0169-0) | Orphenadrine Citrate | A-S Medication Solutions | 2016-06-21 |
| 50090-0169-01 | 30 TABLET, EXTENDED RELEASE in 1 BOTTLE (50090-0169-1) | Orphenadrine Citrate | A-S Medication Solutions | 2014-11-28 |
| 50090-0169-05 | 60 TABLET, EXTENDED RELEASE in 1 BOTTLE (50090-0169-5) | Orphenadrine Citrate | A-S Medication Solutions | 2014-11-28 |
| 60760-0810-30 | 30 TABLET, EXTENDED RELEASE in 1 BOTTLE, PLASTIC (60760-810-... | Orphenadrine Citrate | St. Mary's Medical Park Pharmacy | 2006-10-01 |
| 63187-0122-20 | 20 TABLET, EXTENDED RELEASE in 1 BOTTLE (63187-122-20) | Orphenadrine Citrate | Proficient Rx LP | 2015-02-02 |
| 63187-0122-30 | 30 TABLET, EXTENDED RELEASE in 1 BOTTLE (63187-122-30) | Orphenadrine Citrate | Proficient Rx LP | 2015-02-02 |
| 63187-0122-60 | 60 TABLET, EXTENDED RELEASE in 1 BOTTLE (63187-122-60) | Orphenadrine Citrate | Proficient Rx LP | 2015-02-02 |
| 63187-0122-90 | 90 TABLET, EXTENDED RELEASE in 1 BOTTLE (63187-122-90) | Orphenadrine Citrate | Proficient Rx LP | 2015-02-02 |
| 63187-0632-30 | 30 TABLET, EXTENDED RELEASE in 1 BOTTLE (63187-632-30) | Orphenadrine Citrate | Proficient Rx LP | 2016-01-01 |
| 63187-0632-60 | 60 TABLET, EXTENDED RELEASE in 1 BOTTLE (63187-632-60) | Orphenadrine Citrate | Proficient Rx LP | 2016-01-01 |
| 63187-0632-90 | 90 TABLET, EXTENDED RELEASE in 1 BOTTLE (63187-632-90) | Orphenadrine Citrate | Proficient Rx LP | 2016-01-01 |
| 63629-1564-00 | 56 TABLET, EXTENDED RELEASE in 1 BOTTLE (63629-1564-0) | Orphenadrine Citrate | Bryant Ranch Prepack | 2006-09-22 |
| 63629-1564-01 | 20 TABLET, EXTENDED RELEASE in 1 BOTTLE (63629-1564-1) | Orphenadrine Citrate | Bryant Ranch Prepack | 2006-09-22 |
| 63629-1564-02 | 60 TABLET, EXTENDED RELEASE in 1 BOTTLE (63629-1564-2) | Orphenadrine Citrate | Bryant Ranch Prepack | 2006-09-22 |
| 63629-1564-03 | 100 TABLET, EXTENDED RELEASE in 1 BOTTLE (63629-1564-3) | Orphenadrine Citrate | Bryant Ranch Prepack | 2006-09-22 |
| 63629-1564-04 | 90 TABLET, EXTENDED RELEASE in 1 BOTTLE (63629-1564-4) | Orphenadrine Citrate | Bryant Ranch Prepack | 2006-09-22 |
| 63629-1564-05 | 30 TABLET, EXTENDED RELEASE in 1 BOTTLE (63629-1564-5) | Orphenadrine Citrate | Bryant Ranch Prepack | 2006-09-22 |
| 63629-1564-06 | 28 TABLET, EXTENDED RELEASE in 1 BOTTLE (63629-1564-6) | Orphenadrine Citrate | Bryant Ranch Prepack | 2006-09-22 |
| 63629-1564-07 | 45 TABLET, EXTENDED RELEASE in 1 BOTTLE (63629-1564-7) | Orphenadrine Citrate | Bryant Ranch Prepack | 2006-09-22 |
| 63629-1564-08 | 14 TABLET, EXTENDED RELEASE in 1 BOTTLE (63629-1564-8) | Orphenadrine Citrate | Bryant Ranch Prepack | 2006-09-22 |
| 63629-1564-09 | 120 TABLET, EXTENDED RELEASE in 1 BOTTLE (63629-1564-9) | Orphenadrine Citrate | Bryant Ranch Prepack | 2006-09-22 |
| 66267-0158-20 | 20 TABLET, EXTENDED RELEASE in 1 BOTTLE (66267-158-20) | Orphenadrine Citrate | NuCare Pharmaceuticals, Inc. | 2016-10-12 |
| 66267-0158-30 | 30 TABLET, EXTENDED RELEASE in 1 BOTTLE (66267-158-30) | Orphenadrine Citrate | NuCare Pharmaceuticals, Inc. | 2016-10-12 |
| 67296-1077-01 | 10 TABLET, EXTENDED RELEASE in 1 BOTTLE (67296-1077-1) | Orphenadrine Citrate | RedPharm Drug | 2000-02-15 |
| 68788-9138-01 | 100 TABLET, EXTENDED RELEASE in 1 BOTTLE (68788-9138-1) | Orphenadrine Citrate | Preferred Pharmaceuticals, Inc. | 2011-11-22 |
| 68788-9138-02 | 20 TABLET, EXTENDED RELEASE in 1 BOTTLE (68788-9138-2) | Orphenadrine Citrate | Preferred Pharmaceuticals, Inc. | 2011-11-22 |
| 68788-9138-03 | 30 TABLET, EXTENDED RELEASE in 1 BOTTLE (68788-9138-3) | Orphenadrine Citrate | Preferred Pharmaceuticals, Inc. | 2011-11-22 |
| 68788-9138-04 | 14 TABLET, EXTENDED RELEASE in 1 BOTTLE (68788-9138-4) | Orphenadrine Citrate | Preferred Pharmaceuticals, Inc. | 2011-11-22 |
| 68788-9138-06 | 60 TABLET, EXTENDED RELEASE in 1 BOTTLE (68788-9138-6) | Orphenadrine Citrate | Preferred Pharmaceuticals, Inc. | 2011-11-22 |
| 68788-9138-08 | 120 TABLET, EXTENDED RELEASE in 1 BOTTLE (68788-9138-8) | Orphenadrine Citrate | Preferred Pharmaceuticals, Inc. | 2011-11-22 |
| 68788-9138-09 | 90 TABLET, EXTENDED RELEASE in 1 BOTTLE (68788-9138-9) | Orphenadrine Citrate | Preferred Pharmaceuticals, Inc. | 2011-11-22 |
| 70518-4506-00 | 14 TABLET, EXTENDED RELEASE in 1 BOTTLE, PLASTIC (70518-4506... | ORPHENADRINE CITRATE | REMEDYREPACK INC. | 2025-10-15 |
| 70518-4506-01 | 14 TABLET, EXTENDED RELEASE in 1 BOTTLE, PLASTIC (70518-4506... | ORPHENADRINE CITRATE | REMEDYREPACK INC. | 2025-12-20 |
| 70518-4506-02 | 50 POUCH in 1 BOX (70518-4506-2) / 1 TABLET, EXTENDED RELEA... | ORPHENADRINE CITRATE | REMEDYREPACK INC. | 2026-04-28 |
| 72162-2020-01 | 100 TABLET, EXTENDED RELEASE in 1 BOTTLE (72162-2020-1) | ORPHENADRINE CITRATE | Bryant Ranch Prepack | 2023-05-26 |
| 72162-2020-05 | 500 TABLET, EXTENDED RELEASE in 1 BOTTLE (72162-2020-5) | ORPHENADRINE CITRATE | Bryant Ranch Prepack | 2023-05-26 |
| 72162-2020-06 | 60 TABLET, EXTENDED RELEASE in 1 BOTTLE (72162-2020-6) | ORPHENADRINE CITRATE | Bryant Ranch Prepack | 2023-05-26 |
| 80425-0117-01 | 30 TABLET, EXTENDED RELEASE in 1 BOTTLE (80425-0117-1) | Orphenadrine Citrate ER | Advanced Rx Pharmacy of Tennessee, LLC | 1998-06-19 |
| 80425-0117-02 | 60 TABLET, EXTENDED RELEASE in 1 BOTTLE (80425-0117-2) | Orphenadrine Citrate ER | Advanced Rx Pharmacy of Tennessee, LLC | 2023-08-17 |
| 80425-0340-01 | 30 TABLET, EXTENDED RELEASE in 1 BOTTLE (80425-0340-1) | ORPHENADRINE CITRATE | Advanced Rx Pharmacy of Tennessee, LLC | 2023-05-23 |
| 80425-0340-02 | 60 TABLET, EXTENDED RELEASE in 1 BOTTLE (80425-0340-2) | ORPHENADRINE CITRATE | Advanced Rx Pharmacy of Tennessee, LLC | 2023-08-17 |
Observed labelers:
Bryant Ranch Prepack (13) ·
Preferred Pharmaceuticals, Inc. (7) ·
Proficient Rx LP (7) ·
Advanced Rx Pharmacy of Tennessee, LLC (4) ·
PD-Rx Pharmaceuticals, Inc. (4) ·
A-S Medication Solutions (3)
· +8 more — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.
💲 Pricing (NADAC)
NADAC is CMS's National Average Drug Acquisition Cost — roughly what pharmacies pay to buy the drug. It is an acquisition benchmark, not your copay.
Per ea · median
$0.4750
Range $0.4750–$0.4750
· middle 50% $0.4750–$0.4750
· 3 NDCs
Latest compatible distributions from the CMS NADAC file · dataset watermark 2026-07-10. Prices vary by package and pharmacy; a distribution is shown instead of one misleading number. Rows the dataset is silent on carry no price. No zero-cost conclusion should be drawn.
🗃️ Sources & Limits
Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7
openFDA export observedJul 14, 2026
RxNorm release07/06/2026
Methodology2026-07-full-catalog-v1
- A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
- Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
- Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
- Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.
This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.
Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.