Can Methylprednisolone Be Used To Treat A Urinary Tract Infection (UTI)?

In our latest question and answer, the pharmacist discusses whether or not Medrol (methylprednisolone) can be used to treat a UTI.

Question

Can methylprednisolone be used to treat a urinary tract infection?

Asked by Rudy On May 19, 2021

Answered by
Medical Content Reviewed By HelloPharmacist Staff

Published May 19, 2021
Last updated Jul 04, 2025

Key points

  • Methylprednisolone is a corticosteroid that is usually used to help treat an inflammatory condition.
  • Methylprednisolone has no indicated use for urinary tract infections.
  • A urinary tract infection usually needs to be treated with antibiotics to kill off a bacteria causing the infection. You should contact your physician or go to an immediate care clinic.

Hi Rudi and thanks for reaching out to us. 

Methylprednisolone (or by the brand name, Medrol) is a corticosteroid. It is available as a tablet, an IV solution, and an injectable suspension. It can be used for a number of different conditions, but it’s typically used to treat acute inflammation or a severe allergic reaction.

Urinary tract infections, or more commonly referred to as UTIs are typically a bacterial infection.

Different bacteria can cause UTIs, but the most common is E. coli. In order to kill off the E. coli or whatever other bacteria may be causing the infection, you’ll need to be prescribed an antibiotic.

I would contact your physician or if it’s a more urgent issue, go to an immediate care facility or emergency room. They might need to test your urine to make sure that it is indeed a UTI or test to see which bacteria is causing the problem (and which antibiotics would be an effective treatment against it), but visiting your physician is probably your best option.

As I mentioned earlier, methylprednisolone is a corticosteroid. It will not kill off any bacteria, so it will not resolve your urinary tract infection. 

I hope this helps! Feel free to write us again in the future.

References

  • Medrol Prescribing Information, FDA
  • Solu-Medrol Prescribing Information, FDA
  • Diagnosis and treatment of uncomplicated urinary tract infections, Infectious Disease Clinics

About the Pharmacist

Dr. Brian Staiger, PharmD

Dr. Brian has been practicing pharmacy for over 13 years and has wide-ranging experiences in many different areas of the profession. From retail, clinical, program development, and administrative responsibilities, he's your knowledgeable and go-to source for all your pharmacy and medication-related questions! Dr. Brian Staiger also has herbalist training and educational certificates in the field of medical ethnobotany. Feel free to send him an email at [email protected]! You can also connect with Dr. Brian Staiger on LinkedIn.

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