Can You Take Aleve And Sudafed Together?

In our latest question and answer, the pharmacist discusses whether or not Aleve and Sudafed can be taken together.

Question

Hello, can Sudafed for sinus and Aleve for body ache be taken together?

Asked by Obet On Nov 11, 2022

Answered by
Medical Content Reviewed By HelloPharmacist Staff

Published Nov 11, 2022
Last updated Apr 30, 2024

Key points

  • There is no known drug interaction between Aleve (naproxen) and Sudafed (pseudoephedrine).
  • The active ingredients in Sudafed and Aleve can be found in a single pill (Aleve-D).

Answer

Yes, Sudafed (pseudoephedrine), can safely be taken with Aleve (naproxen). There is no drug interaction between the two.

In fact, these two drugs are available together in combination in a single product, Aleve-D Sinus & Cold.

Aleve D image

It's not clear in your question if you are referring to Sudafed, which contains pseudoephedrine, or Sudafed PE, which contain phenylephrine. Regardless, Aleve can be taken with either drug safely and both represent an effective treatment for nasal congestion and other cold/flu symptoms.

If you are looking for Aleve-D at your local store, remember that you can only buy it at the pharmacy as it's stored behind the counter.

Aleve-D is an over-the-counter product and doesn't require a prescription but based on the regulations in the Combat Methamphetamine Epidemic Act, it needs to be stored securely and you need to show your ID for it.

What Is Aleve?

Naproxen is used to reduce fever and to relieve mild pain from headaches, muscle aches, arthritis, menstrual periods, the common cold, toothaches, and backaches.

Naproxen is in a class of medications called NSAIDs and works by stopping the body's production of a substance that causes pain, fever, and inflammation. It is similar to ibuprofen, but has a longer duration of action (around 8 to 12 hours per dose).

What Is Sudafed?

Pseudoephedrine is used to relieve nasal congestion caused by colds, allergies, and hay fever. It is also used to temporarily relieve sinus congestion and pressure.

Pseudoephedrine is in a class of medications called nasal decongestants and works by causing narrowing of the blood vessels in the nasal passages.

Final Words

Thanks for your question! We are always happy to help.

References

  • Combat Methamphetamine Epidemic Act, DEA
  • Naproxen Monograph, PubChem
  • Pseudoephedrine Monograph, PubChem
  • Phenylephrine Monograph, PubChem

About the Pharmacist

Dr. Brian Staiger, PharmD

Dr. Brian has been practicing pharmacy for over 13 years and has wide-ranging experiences in many different areas of the profession. From retail, clinical, program development, and administrative responsibilities, he's your knowledgeable and go-to source for all your pharmacy and medication-related questions! Dr. Brian Staiger also has herbalist training and educational certificates in the field of medical ethnobotany. Feel free to send him an email at [email protected]! You can also connect with Dr. Brian Staiger on LinkedIn.

Recent Questions