Can You Take DayQuil With Allegra?

In our latest question and answer, the pharmacist discusses the use of Allegra and DayQuil together.


Hi, can I combine Allegra and DayQuil? Thanks for your help.

Asked by Paul On Jul 03, 2022

Answered by
Medical Content Reviewed By HelloPharmacist Staff

Published Jul 03, 2022
Last updated Jul 03, 2022

Key points

  • There is no drug interaction between Allegra (fexofenadine) and DayQuil.

Hello and thanks for reaching out to us! It's always a good idea to look into whether or not certain drugs interact with one another.

The good news here is that DayQuil and Allegra are safe to take together. There is no drug interaction between them.

In fact, there are a variety of DayQuil products on the market, and Allegra is safe to take with all of them. DayQuil products include:

  • DayQuil Cold & Flu
  • DayQuil Severe
  • DayQuil HBP
  • DayQuil VapoCool
  • DayQuil Honey

Allegra contains the antihistamine fexofenadine. None of the DayQuil products listed above contain an antihistamine nor do they interact with any antihistamine.

It is important to note that NyQuil contains an antihistamine (doxylamine), and generally should not be taken with other antihistamines, which includes Allegra.

Thanks again for your question and please feel free to reach out to us again in the future.


About the Pharmacist

Dr. Brian Staiger, PharmD

Dr. Brian has been practicing pharmacy for over 11 years and has wide-ranging experiences in many different areas of the profession. From retail, clinical and administrative responsibilities, he's your knowledgeable and go-to source for all your pharmacy and medication-related questions! Feel free to send him an email at! You can also connect with Dr. Brian Staiger on LinkedIn.

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