Doxylamine

Doxylamine on the U.S. market: products, makers and brands

How Doxylamine appears in the FDA’s National Drug Code Directory — including its dosage forms, strengths, brand names, manufacturers, and FDA-listed product records. These are directory records, not sales or prescription volume.

54 companies list 139 Doxylamine product records with the FDA, mostly as tablet, oral solution, capsule; the earliest marketing or approval year on record is 1948. Brand names on the directory include Aldex AN, Nighttime Sleep Aid, Unisom SleepTabs and 13 more; the rest are generics.

Also listed with the FDA, not a patient dose form: Powder (11) — bulk drug substance sold to compounders/manufacturers and multi-item kits. These aren’t counted in the dose-form total above.

Share of FDA-listed product records by manufacturer — FDA National Drug Code Directory. Record counts are not sales or prescription volume.

How widely Doxylamine is used (Medicaid data)

A general measure of how commonly Doxylamine is prescribed, based on Medicaid — one of the largest public drug programs. The figure below is prescriptions filled in Q1–Q4 2025, summed across every form and brand of the drug.

Think of this as a proxy for how widely Doxylamine is used, drawn from freely available public data. Medicaid is just one program — these numbers don’t include Medicare, other government coverage, or commercial and cash-pay prescriptions, so real-world use is higher than what’s shown here.

How commonly is Doxylamine prescribed? Of the 1,601 medications we measure, Doxylamine ranks #880 by Medicaid prescriptions — more than 45% of them.

Source: Medicaid State Drug Utilization Data (CMS), aggregated by generic ingredient — summed across every NDC (all brands, strengths, salt forms and dosage forms) of Doxylamine, and across all states and both fee-for-service and managed-care claims. A general popularity signal; it excludes Medicare, commercial insurance and cash prescriptions, so it is not total U.S. use. Based on the 5 of 108 listed Doxylamine NDCs with Medicaid activity.

Compare Doxylamine products

A representative set of FDA-listed product records for Doxylamine — across manufacturers, strengths, and dosage forms, grouped by form with each product’s manufacturer and how the FDA approved it. The same medicine may be made and packaged by different companies, so a single drug can have many directory entries. (It’s also why a refill can look different — a new shape, color, or box — even though it contains the same medication.)

Showing 139 of 139 products — FDA National Drug Code Directory. See every product, package size and price: browse all 139 Doxylamine NDCs →

Doxylamine brand names

Doxylamine is sold under 16 brand names in the FDA directory — Aldex AN, Nighttime Sleep Aid, Unisom SleepTabs, Unisom and others. A brand and its generic contain the same active ingredient; the brand name belongs to one company's product.

Who makes Doxylamine: manufacturers and labelers

40 companies list Doxylamine products with the FDA. By number of product records, the largest are The Procter & Gamble Manufacturing Company, Kroger Company, Rite Aid Corporation. Labelers include manufacturers and repackagers; the product in your bottle depends on which one your pharmacy stocks.

…and 16 more on the FDA NDC directory.

Doxylamine compared with similar medicines

Medicines in the same class as Doxylamine that we cover: Benztropine, Hydroxyzine. The table compares what the FDA directory records for each — how it is sold, the dose forms on the market, how many companies list it (makers, repackagers and distributors), and the earliest FDA record on file. Same class does not mean interchangeable; your prescriber chooses among them for reasons the label alone does not show.

Source: FDA National Drug Code Directory and Drugs@FDA, as summarized on each medicine's page. A dash means the fact is not on record.