Can You Take Hawthorn Supplements With Azithromycin (Z-PACK)?

In our latest question and answer, the pharmacist discusses if azithromycin can safely be taken with hawthorn supplements.

Question

Is it okay to take Hawthorn berry with a z-pack antibiotic?

Asked by Ron B On Mar 03, 2024

Answered by
Medical Content Reviewed By HelloPharmacist Staff

Published Mar 04, 2024
Last updated Apr 24, 2024

Key points

  • There is no known interaction between azithromycin and hawthorn, however, data is limited.
  • Be sure to speak with your doctor before adding on any dietary supplement to your current medication regimen.

Answer

Thank you for contacting us!

While we have several potential drug interactions listed for Hawthorn, our drug-herbal interaction checker shows no interaction with azithromycin.

Additional Details

Hawthorn is known to have potential interactions with drugs affecting blood pressure and blood coagulation, such as anticoagulant/antiplatelet drugs, beta-blockers, calcium channel blockers, digoxin, nitrates, and phosphodiesterase-5 inhibitors. These interactions are due to potential additive effects on blood pressure, heart rate, and coronary vasodilation, none of which are a concern with azithromycin.

Most interactions involving azithromycin relate to impaired absorption when taken with other drugs or additive side effects. For example, azithromycin has many listed drug interactions due to the potential to affect heart rhythm (prolong the 'QT interval'). Hawthorn is not known to affect the absorption of azithromycin or cause additive side effects.

Overall, although there are no specific studies on the interaction between azithromycin and hawthorn that I could find, based on their known mechanisms of action and potential side effects, a clinically significant interaction between the two is not expected.

Final Words

Thank you for contacting us, and please do so again anytime!

References

About the Pharmacist

Dr. Brian Staiger, PharmD

Dr. Brian has been practicing pharmacy for over 13 years and has wide-ranging experiences in many different areas of the profession. From retail, clinical, program development, and administrative responsibilities, he's your knowledgeable and go-to source for all your pharmacy and medication-related questions! Dr. Brian Staiger also has herbalist training and educational certificates in the field of medical ethnobotany. Feel free to send him an email at [email protected]! You can also connect with Dr. Brian Staiger on LinkedIn.

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