Can You Take Wegovy With Apple Cider Vinegar?

In our latest question and answer, the pharmacist discusses whether or not it is safe to take Wegovy and apple cider vinegar together.

2 min read Updated Jun 2026 Read by 3,293 people
Can You Take Wegovy With Apple Cider Vinegar?
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Fran asked

I just started Wegovy injections last week. Is it safe to take Apple Cider Vinegar tablets while on this medication? I want to improve my chances of weight loss.

Jul 15, 2023
The quick answer
  • There are no known interactions between Wegovy injections and apple cider vinegar, and they are generally considered safe to take together. Both can potentially lower blood sugar levels, which is mostly a theoretical concern with no published reports of problems occurring in real life. It's important to discuss any new supplements with your healthcare provider, especially if you have diabetes.
A quick summary of Dr. Brian Staiger, PharmD's full answer below, condensed by AI from that answer only (not from any outside source). The pharmacist's answer is the source of record.
Medications in this answer — tap to explore

Quick Answer

There are no known interactions between Wegovy (semaglutide) injections and Apple Cider Vinegar (ACV). They are generally considered safe to take together.

Detailed Answer

Wegovy (semaglutide) is a medication used for weight management. It belongs to a class of drugs called glucagon-like peptide-1 receptor agonists (GLP-1 agonists), which work by stimulating insulin release, suppressing glucagon secretion, slowing down gastric emptying, and increasing satiety. These actions help reduce appetite and promote weight loss. The active ingredient in Wegovy (semaglutide) is also the active ingredient in the diabetes drug Ozempic.

Apple Cider Vinegar (ACV) is a popular dietary supplement and is most often used to help manage blood glucose levels and weight.

It is important to point out that both Wegovy and Apple Cider Vinegar are associated with a decrease in blood sugar levels. Theoretically, this could increase the risk of blood sugar dropping too low (i.e., hypoglycemia). This potential interaction is mentioned in our interaction checker (ACV With Semaglutide).

However, neither medication is strongly associated with hypoglycemia on their own, and there are no published reports of the combination causing it. This interaction appears to be more theoretical and not something that commonly occurs in real-life clinical situations. Nevertheless, it is important to be aware of this possibility, especially if you are diabetic.

Final Words

In summary, there are no known interactions between Wegovy and ACV tablets. However, it is always important to discuss any new dietary supplements or medications with your healthcare provider to ensure their safety and effectiveness in your specific case.

References & sources
  1. Effect and mechanisms of action of vinegar on glucose metabolism, lipid profile, and body weight — Oxford Academic
  2. The effect of apple vinegar consumption on glycemic indices, blood pressure, oxidative stress, and homocysteine in patients with type 2 diabetes and dyslipidemia: A randomized controlled clinical trial — PubMed
Glossary — Terms in This Answer
Semaglutide
An active ingredient in weight management and diabetes medications that helps reduce appetite and lower blood sugar.
Glucagon-like peptide-1 receptor agonists (GLP-1 agonists)
A class of drugs that work by stimulating insulin release and reducing appetite to help with weight loss and blood sugar control.
Insulin
A hormone that helps regulate blood sugar levels by allowing cells to take up glucose from the bloodstream.
Glucagon
A hormone that raises blood sugar levels by stimulating the release of stored glucose in the body.
Gastric emptying
The process of food moving from the stomach into the small intestine for digestion.
Satiety
The feeling of fullness that makes you stop eating.
Hypoglycemia
A condition where blood sugar drops to dangerously low levels.
Dietary supplement
A product taken by mouth containing ingredients intended to supplement the diet and support health.
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Dr. Brian Staiger, PharmD
About the pharmacist

Dr. Brian Staiger, PharmD

Clinical Pharmacy

Doctor of Pharmacy, board certified clinical pharmacist (BCPS), American Herbalist Guild, Medication Therapy Management certified

Brian Staiger, PharmD, BCPS, is a licensed pharmacist with more than 13 years of experience across retail pharmacy, clinical pharmacy, medication safety, pharmacy program development, and healthcare administration. He is the founder of HelloPharmacist.com, where he helps patients...

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