Is Amoxicillin Safe With Losartan, Carvedilol And Prasugrel?

In our latest question and answer, the pharmacist answers a question regarding drug interactions with amoxicillin.

2 min read Updated Jun 2026 4,835 views
Is Amoxicillin Safe With Losartan, Carvedilol And Prasugrel?
Share
Babby asked

I take losartan, carvedilol and prasugrel. Can I take amoxicillin?

Nov 08, 2022
The quick answer
  • Amoxicillin is safe to take with losartan, carvedilol, and prasugrel as there are no drug interactions between them.
  • Amoxicillin should not interfere with treatment of high blood pressure, blood clots, or heart attack recovery.
  • Amoxicillin is one of the safer antibiotics when it comes to serious drug interactions compared to other common antibiotics.
A quick summary of Dr. Brian Staiger, PharmD's full answer below, condensed by AI from that answer only (not from any outside source). The pharmacist's answer is the source of record.

Answer

There are no drug interactions between amoxicillin, Cozaar (losartan), Coreg (carvedilol) and Effient (prasugrel). They are considered safe to take together.

Additionally, amoxicillin shouldn't interfere with what you are using these drugs for.

You don't mention exactly what conditions you are treating, based on your medication list, I'm assuming you have had a recent blood clot or heart attack. You may be treating high blood pressure as well. A short course of amoxicillin should not affect any of these conditions.

Amoxicillin is one of the safer antibiotics when it comes to serious drug interactions. While it does have clinically significant interactions with some drugs, it has less than other common antibiotics, such as tetracyclines and fluoroquinolones.

What is Amoxicillin?

Amoxicillin is an antibiotic used to treat certain infections caused by bacteria, such as pneumonia; bronchitis (infection of the airway tubes leading to the lungs); and infections of the ears, nose, throat, urinary tract, and skin.

Amoxicillin is in a class of medications called penicillin-like antibiotics and works by stopping the growth of bacteria.

What Is Losartan?

Losartan is used alone or in combination with other medications to treat high blood pressure and various other cardiovascular conditions.

Losartan is in a class of medications called angiotensin II receptor antagonists and works by blocking the action of certain natural substances that tighten the blood vessels, allowing the blood to flow more smoothly and the heart to pump more efficiently.

What Is Coreg?

Carvedilol is used to treat heart failure (condition in which the heart cannot pump enough blood to all parts of the body) and high blood pressure. It also is used to treat people who have had a heart attack.

Carvedilol is in a class of medications called beta-blockers and works by relaxing blood vessels and slowing heart rate to improve blood flow and decrease blood pressure.

What Is Prasugrel?

Prasugrel is used along with aspirin to prevent serious or life-threatening problems with the heart and blood vessels in people who have had a heart attack or severe chest pain.

Prasugrel is in a class of medications called anti-platelet medications and works by preventing platelets (a type of blood cell) from collecting and forming clots that may cause a heart attack or stroke.

Final Words

I appreciate you connecting with us and asking! Reach back out anytime.

References & sources
  1. Amoxil Prescribing Information — AccessFDA
  2. Carvedilol Monograph — PubChem
  3. Losartan Monograph — PubChem
  4. Prasugrel Monograph — PubChem
  5. Amoxicillin Monograph — PubChem
Glossary — Terms in This Answer
Drug interactions
When two or more medications affect how each other works in your body, potentially causing problems or reducing effectiveness.
Antibiotic
A medication used to kill bacteria or stop their growth to treat infections.
Angiotensin II receptor antagonists
A class of blood pressure medications that work by blocking natural substances that narrow blood vessels.
Beta-blockers
A class of medications that slow heart rate and relax blood vessels to lower blood pressure and improve heart function.
Anti-platelet medications
Medications that prevent blood cells called platelets from sticking together to form clots.
Penicillin-like antibiotics
A class of antibiotics derived from or similar to penicillin that kill bacteria by disrupting their cell walls.
Heart failure
A condition where the heart cannot pump enough blood to meet the body's needs.
Platelets
Tiny blood cells that stick together to form clots and stop bleeding.
Did this answer your question?
Dr. Brian Staiger, PharmD
About the pharmacist

Dr. Brian Staiger, PharmD

Clinical Pharmacy

Doctor of Pharmacy, board certified clinical pharmacist (BCPS), American Herbalist Guild, Medication Therapy Management certified

Brian Staiger, PharmD, BCPS, is a licensed pharmacist with more than 13 years of experience across retail pharmacy, clinical pharmacy, medication safety, pharmacy program development, and healthcare administration. He is the founder of HelloPharmacist.com, where he helps patients...

More answers from Brian →
Ask a Pharmacist