Is Zarbee's Safe With Dimetapp?

In our latest question and answer, the pharmacist discusses whether or not Dimetapp is safe with Zarbee's products.

2 min read Updated Jun 2026 Read by 5,998 people
Is Zarbee's Safe With Dimetapp?
Share
Skyler asked

My doctor recommended that I give Dimetapp to my child and I just want to make sure it is okay to mix that with Zarbee's Cough Syrup + Mucus.

Jul 06, 2022
The quick answer
  • Zarbee's Cough + Mucus contains no ingredients known to interact with Dimetapp products and is considered safe to use together.
  • The ingredients in Zarbee's Cough + Mucus are generally safe to combine with over-the-counter medications.
A quick summary of Dr. Brian Staiger, PharmD's full answer below, condensed by AI from that answer only (not from any outside source). The pharmacist's answer is the source of record.

Thanks for reaching out! We've been getting a lot of questions regarding Zarbee's products recently, and are always more than happy to answer them.

First and foremost, I want to mention that there are several different Dimetapp products on the market, and they all contain different ingredients.

Nevertheless, Zarbee's Cough + Mucus does not contain any ingredients known to interact with any of the drugs contained in Dimetapp products (including Dimetapp Cold & Cough). They are considered safe to use together. 

What Is In Zarbee's Cough + Mucus

Zarbees Cough Syrup and Mucus Box and Bottle
Zarbee's Cough + Mucus contains the following ingredients:

  • Dark Honey
  • English Ivy Extract
  • Ascorbic Acid
  • Zinc Gluconate
  • Water
  • Citric Acid
  • Grapefruit Seed Extract
  • Natural Flavor

None of these ingredients have reported drug interactions and are generally considered to be safe to combine with over-the-counter medications. In fact, none of these are considered 'drug' products, which is why the labeling on Zarbee's Cough + Mucus says 'Supplement Facts' instead of 'Drug Facts'.

What Is In Dimetapp Cold & Cough?

Dimetapp Cough Cold

Since you mentioned Dimetapp Cough, I am assuming you are referring to Dimetapp Cold & Cough. It contains:

  • Brompheniramine maleate (Antihistamine)
  • Dextromethorphan HBr (Cough Suppressant)
  • Phenylephrine HCl (Nasal Decongestant)

As mentioned, these drugs are considered safe with the ingredients in Zarbee's Cough + Mucus.

Final Words

Thanks again for reaching out! I hope your child starts to feel better soon.

References & sources
  1. Brompheniramine Monograph — PubChem
  2. Phenylephrine Monograph — PubChem
  3. Dextromethorphan Monograph — PubChem
Glossary — Terms in This Answer
Antihistamine
A medication that blocks histamine to relieve allergy symptoms like sneezing and itching.
Cough Suppressant
A medication that reduces the urge to cough.
Nasal Decongestant
A medication that relieves nasal congestion and stuffiness.
Drug interactions
When two medications taken together affect how each other works in the body.
Over-the-counter medications
Medicines you can buy without a doctor's prescription.
Ascorbic Acid
Vitamin C, a nutrient that supports immune function.
Zinc Gluconate
A form of zinc, a mineral that may help support immune health.
Did this answer your question?
Dr. Brian Staiger, PharmD
About the pharmacist

Dr. Brian Staiger, PharmD

Clinical Pharmacy

Doctor of Pharmacy, board certified clinical pharmacist (BCPS), American Herbalist Guild, Medication Therapy Management certified

Brian Staiger, PharmD, BCPS, is a licensed pharmacist with more than 13 years of experience across retail pharmacy, clinical pharmacy, medication safety, pharmacy program development, and healthcare administration. He is the founder of HelloPharmacist.com, where he helps patients...

More answers from Brian →
Ask a Pharmacist