Taking DayQuil With Aleve and Hydrocodone/APAP 7.5/325

Answer

Thanks for reaching out!

I discuss the answer in detail below, but here are some quick points:

• Aleve (naproxen) and DayQuil (which contains acetaminophen) are generally considered safe to take together.
• Hydrocodone/APAP 7.5/325 mg contains acetaminophen, and taking it with DayQuil could result in exceeding the maximum recommended dose of acetaminophen, which can lead to serious liver damage. They should generally be separated from one another and you need to be sure you keep track of how much acetaminophen you are taking.

DayQuil Contains Acetaminophen

It is important to note that DayQuil is a multi-ingredient product that contains several drugs. 'Original' DayQuil contains:

• Acetaminophen (analgesic)
• Phenylephrine (decongestant)
• Dextromethorphan (cough suppressant)

Since DayQuil contains several ingredients, it is important to stay on top of all the other medications you are taking to make sure you aren't taking too much of any one drug.

This is especially true with acetaminophen, which is the most commonly used analgesic in over-the-counter products that are used to relieve pain and has a well-documented history of being a drug people accidentally overdose on.

DayQuil With Aleve

DayQuil is considered safe to take with Aleve as there are no known interactions between the two.

Even though Aleve is a pain reliever, it contains naproxen, an NSAID (non-steroidal anti-inflammatory drug), which is not related to Tylenol (acetaminophen). NSAIDs and Tylenol are generally considered safe to take together.

In fact, there is a product on the market that contains an NSAID and acetaminophen in a single pill (Advil Dual Action).

DayQuil With Hydrocodone/APAP

The other drug in your question is where there is some concern.

As mentioned, DayQuil contains acetaminophen. Hydrocodone/APAP 7.5/325 mg also contains acetaminophen (APAP stands for acetaminophen). Therefore, taking both could result in exceeding the maximum recommended dose of acetaminophen. You need to be very careful about combining products that contain acetaminophen.

Now, the amount of acetaminophen in one dose of DayQuil is 650mg. One tablet of hydrocodone/APAP 7.5/325 mg contains 325mg of acetaminophen.

The maximum recommended dose of acetaminophen at one time (for adults) is 1,000mg. The maximum daily dose of acetaminophen is 4,000mg.

So, you need to consider a few things here:

• Do not take more than 1,000mg of acetaminophen at one time.
• Every dose of acetaminophen should be separated by at least four to six hours.
• Do not take more than 4,000mg of acetaminophen per day.

You could take one dose of DayQuil and one tablet of hydrocodone/APAP 7.5/325 mg and still be under the 1,000mg per dose limit of acetaminophen, but again, it is very important to be aware of your overall dosages and total daily dose to be sure you stay within the dosing recommendations to avoid adverse reactions.

Final Words

I hope this was helpful! Thanks for reaching out!