Aceclofenac
95 interactions 5 explained in plain English
Medically reviewed by
Dr. Brian Staiger, PharmD, BCPS
· Updated Jul 4, 2026
· Editorial policy
· Data sources
Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →
Most serious with:
Ketorolac Nasal Spray
Ketorolac Injection
Ketorolac
Ketorolac Ophthalmic
Budesonide Oral Inhalation
Melphalan
Major
Aceclofenac Amitriptyline Elavil Explained An increased risk of bleeding Details Aceclofenac Sertraline Explained An increased risk of bleeding Details Aceclofenac Apixaban Eliquis Explained An increased risk of bleeding Details Aceclofenac Aspirin Acuprin® An increased risk of bleeding, decreased renal function, and an increased risk of gastrointestinal adverse events Details Aceclofenac Aspirin Rectal Aspirin An increased risk of bleeding, decreased renal function, and an increased risk of gastrointestinal adverse events Details Aceclofenac Betrixaban Bevyxxa® An increased risk of bleeding Details Aceclofenac Anagrelide Agrylin An increased risk of bleeding Details Aceclofenac Bromfenac Ophthalmic Bromday® Increased risk of bleeding Details Aceclofenac Budesonide Entocort Increased risk of gastrointestinal ulcer or bleeding Details Aceclofenac Budesonide Nasal Spray Rhinocort Increased risk of gastrointestinal ulcer or bleeding Details Aceclofenac Budesonide Oral Inhalation Pulmicort Increased risk of gastrointestinal ulcer or bleeding Details Aceclofenac Clopidogrel Plavix An increased risk of bleeding Details Aceclofenac Cyclosporine Injection Atopica An increased risk of cycloSPORINE nephrotoxicity Details Aceclofenac Cyclosporine Ophthalmic Cequa An increased risk of cycloSPORINE nephrotoxicity Details Aceclofenac Dabigatran Pradaxa® An increased risk of bleeding Details Aceclofenac Dabigatran Etexilate An increased risk of bleeding Details Aceclofenac Dalteparin Injection Fragmin An increased risk of bleeding Details Aceclofenac Deferiprone Ferriprox Decreased deferiprone clearance and increased deferiprone plasma concentrations Details Aceclofenac Deflazacort Emflaza Increased risk of gastrointestinal ulcer or bleeding Details Aceclofenac Dexamethasone Injection Decadron Increased risk of gastrointestinal ulcer or bleeding Details Aceclofenac Dexamethasone Ophthalmic Dexacidin® (as a combination product containing Dexamethasone, Neomycin, Polymyxin B) Increased risk of gastrointestinal ulcer or bleeding Details Aceclofenac Digoxin Cardoxin® Increased digoxin exposure and prolonged half-life of digoxin Details Aceclofenac Dipyridamole Permole® An increased risk of bleeding Details Aceclofenac Edoxaban Savaysa An increased risk of bleeding Details Aceclofenac Emtricitabine Emtriva Increased emtricitabine exposure and an increased risk of emtricitabine-related adverse effects Details Aceclofenac Enoxaparin Lovenox An increased risk of bleeding Details Aceclofenac Enoxaparin Injection Lovenox An increased risk of bleeding Details Aceclofenac Epoprostenol Flolan An increased risk of bleeding Details Aceclofenac Etodolac Lodine Increased risk of bleeding Details Aceclofenac Fenoprofen Fenopron Increased risk of bleeding Details Aceclofenac Flurbiprofen Ansaid Increased risk of bleeding Details Aceclofenac Flurbiprofen Ophthalmic Ocufen Increased risk of bleeding Details Aceclofenac Fondaparinux Arixtra An increased risk of bleeding Details Aceclofenac Fondaparinux Injection Arixtra An increased risk of bleeding Details Aceclofenac Furosemide Injection Disal Reduced diuretic effectiveness and possible nephrotoxicity Details Aceclofenac Heparin An increased risk of bleeding Details Aceclofenac Heparin Injection Lipo-Hepin® An increased risk of bleeding Details Aceclofenac Hydrocortisone Ala-Cort Increased risk of gastrointestinal ulcer or bleeding Details Aceclofenac Hydrocortisone Injection A-Hydrocort® Increased risk of gastrointestinal ulcer or bleeding Details Aceclofenac Ibuprofen Addaprin Increased risk of bleeding DetailsNo interactions on this page match that filter — try the next page or clear the filter.
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