Acitretin

Name: Acitretin Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

25 interactions 112 cited references

Also sold as: Soriatane®

About Acitretin

Acitretin is used to treat severe psoriasis (abnormal growth of skin cells that causes red, thickened, or scaly skin). Acitretin is in a class of medications called retinoids. The way acitretin works is not known. Read the full Acitretin drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 11, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Omadacycline Injection Minocycline Topical Eravacycline Injection Doxycycline Injection Tigecycline Tetracycline

18 Contraindicated 2 Major 5 Moderate

All (25) Contraindicated (18) Major (2) Moderate (5)

Moderate

Acitretin Fosphenytoin Cerebyx Increased free phenytoin concentrations and risk of toxic effects Details Acitretin Levonorgestrel After banger Loss of contraceptive effectiveness Details Acitretin Phenytoin Dilantin Increased free phenytoin concentrations and risk of toxic effects Details Acitretin Vitamin A Aquasol A Increased risk of vitamin A toxicity Details Acitretin Levonorgestrel Intrauterine System Kyleena Loss of contraceptive effectiveness Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.