Alogliptin

Name: Alogliptin Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

129 interactions 209 cited references

Also sold as: Nesina Nesina®

About Alogliptin

Alogliptin is used along with diet and exercise to lower blood sugar levels in patients with type 2 diabetes (condition in which blood sugar is too high because the body does not produce or use insulin normally). Alogliptin is in a class of medications called dipeptidyl peptidase-4 (DPP-4) inhibitors. It works by incre… Read the full Alogliptin drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Colchicine Insulin Degludec (Rdna Origin) Injection Abiraterone Abiraterone Acetate Abiraterone Acetate, Micronized Ofloxacin Otic

1 Contraindicated 81 Major 47 Moderate

All (129) Contraindicated (1) Major (81) Moderate (47)

Moderate

Alogliptin Timolol Betimol Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Alogliptin Tolazamide Tolinase® An increased risk of hypoglycemia Details Alogliptin Tolbutamide Orinase® An increased risk of hypoglycemia Details Alogliptin Trandolapril Mavik® An increased risk of hypoglycemia Details Alogliptin Tranylcypromine Parnate An increased risk of hypoglycemia Details Alogliptin Betaxolol Ophthalmic Betoptic® Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Alogliptin Levobunolol Ophthalmic AKBeta® Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.