Amiloride

Name: Amiloride Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

49 interactions 3 explained in plain English

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Acetaminophen And Codeine Captopril Naproxen Arsenic Trioxide Bromfenac Ophthalmic Benazepril

42 Major 7 Moderate

All (49) Major (42) Moderate (7)

Moderate

Amiloride Aliskiren Tekturna Hyperkalemia Details Amiloride Asenapine Transdermal Patch Secuado An increased risk of hypotension Details Amiloride Digoxin Cardoxin® Decreased digoxin effectiveness Details Amiloride Irbesartan Avapro Increased risk of hyperkalemia Details Amiloride Lithium Carbonate Lithobid Increased lithium concentrations and lithium toxicity (weakness, tremor, excessive thirst, confusion) Details Amiloride Losartan Arbli Increased risk of hyperkalemia Details Amiloride Metformin Fortamet® An increased risk of hyperglycemia and potential loss of glycemic control Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.