Amlodipine

195 interactions 821 cited references
Also sold as: Amvaz® Katerzia Katerzia® Norliqva Norvasc Norvasc® Sdamlo
About Amlodipine

Amlodipine is a calcium channel blocker used to treat high blood pressure, chest pain, and narrowing of heart blood vessels. Read the full Amlodipine drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 10, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Major

Amlodipine Verapamil Calan Increased amLODIPine exposure and an increased risk of hypotension and edema Details Amlodipine Vinblastine Velban® Reduced amLODIPine exposure Details Amlodipine Voriconazole Vfend An increased amLODIPine exposure, an increased risk of hypotension and edema, an increased voriconazole exposure and an increased... Details Amlodipine Voxelotor Oxbryta Increased amLODIPine exposure and an increased risk of hypotension and edema Details Amlodipine Warfarin Coumadin Increased warfarin exposure and an increased INR Details Amlodipine Zanubrutinib Brukinsa Reduced amLODIPine exposure Details Amlodipine Bexarotene Topical Targretin Reduced amLODIPine exposure Details Amlodipine Brivaracetam Injection Briviact Reduced amLODIPine exposure Details Amlodipine Clonidine Transdermal Patch Catapres An increased risk of worsen sinus node dysfunction and atrioventricular node conduction, an increased risk of bradycardia and AV b... Details Amlodipine Cyclosporine Injection Atopica Increased cycloSPORINE exposure and an increased risk of cycloSPORINE toxicity (renal dysfunction, cholestasis, paresthesias) Details Amlodipine Cyclosporine Ophthalmic Cequa Increased cycloSPORINE exposure and an increased risk of cycloSPORINE toxicity (renal dysfunction, cholestasis, paresthesias) Details Amlodipine Dexamethasone Injection Decadron Reduced amLODIPine exposure Details Amlodipine Dexamethasone Ophthalmic Dexacidin® (as a combination product containing Dexamethasone, Neomycin, Polymyxin B) Reduced amLODIPine exposure Details Amlodipine Ketoconazole Topical Extina® Foam Increased calcium channel blockers that are CYP3A4 substrates exposure and an increased risk of calcium channel blockers that are... Details Amlodipine Lacosamide Injection Motpoly An increased risk of AV block, bradycardia, and ventricular tachyarrhythmia Details Amlodipine Lenacapavir Injection Sunlenca Increased amLODIPine exposure and an increased risk of hypotension and edema Details Amlodipine Lenacapavir Oral Sunlenca Increased amLODIPine exposure and an increased risk of hypotension and edema Details Amlodipine Letermovir Injection Prevymis Increased amLODIPine exposure and an increased risk of hypotension and edema Details Amlodipine Melphalan Injection Alkeran An increased risk of severe hypotension Details Amlodipine Nafcillin Injection Unipen® Injection Reduced amLODIPine exposure Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.