Anagrelide

434 interactions 313 cited references
Also sold as: Agrylin Agrylin®
About Anagrelide

Anagrelide is used to decrease the number of platelets (a type of blood cell that is needed to control bleeding) in the blood of patients who have a bone marrow disorder, in which the body makes too many of one or more types of blood cells, such as essential thrombocythemia (condition in which the body makes too many p… Read the full Anagrelide drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Piperaquine Bepridil Mesoridazine Abrocitinib Pimozide Levoketoconazole
15 Contraindicated 376 Major 41 Moderate 2 Minor
All (434) Contraindicated (15) Major (376) Moderate (41) Minor (2)

Moderate

Anagrelide Anise Increased risk of bleeding Details Anagrelide Astragalus Increased risk of bleeding Details Anagrelide Bilberry Increased risk of bleeding Details Anagrelide Black Currant Increased risk of bleeding Details Anagrelide Bladderwrack Increased risk of bleeding Details Anagrelide Bogbean Increased risk of bleeding Details Anagrelide Boldo Increased risk of bleeding Details Anagrelide Borage Increased risk of bleeding Details Anagrelide Capsaicin Arthricare for Women Moisturizing Increased risk of bleeding Details Anagrelide Carbamazepine Carbatrol Decreased anagrelide exposure Details Anagrelide Cat's Claw Increased risk of bleeding Details Anagrelide Chaparral Increased risk of bleeding Details Anagrelide Clove Oil Increased risk of bleeding Details Anagrelide Dandelion Increased risk of bleeding Details Anagrelide Donanemab-Azbt An increased risk of amyloid related imaging abnormalities (ARIA), or intracerebral hemorrhage Details Anagrelide Evening Primrose Increased risk of bleeding Details Anagrelide Feverfew Increased risk of bleeding Details Anagrelide Garlic Increased risk of bleeding Details Anagrelide Ginkgo Increased platelet inhibition which may increase the risk of bleeding Details Anagrelide Guggul Increased risk of bleeding Details Anagrelide Hawthorn Increased risk of bleeding Details Anagrelide Ibritumomab Tiuxetan An increased risk of bleeding and hemorrhage Details Anagrelide Icosapent Ethyl Vascepa An increased risk of bleeding Details Anagrelide Iloprost Aurlumyn Increased risk of bleeding Details Anagrelide Kava Increased risk of bleeding Details Anagrelide Lecanemab-Irmb An increased risk of amyloid related imaging abnormalities or intracerebral hemorrhage Details Anagrelide Licorice Increased risk of bleeding Details Anagrelide Meadowsweet Increased risk of bleeding Details Anagrelide Motherwort Increased risk of bleeding Details Anagrelide Omega-3-Acid Ethyl Esters Lovaza Increased risk of bleeding Details Anagrelide Omega-3-Carboxylic Acids Increased risk of bleeding Details Anagrelide Pentoxifylline Pentoxil® An increased risk of bleeding Details Anagrelide Phenytoin Dilantin Decreased anagrelide exposure Details Anagrelide Rifampin Rifadin Decreased anagrelide exposure Details Anagrelide Skullcap Increased risk of bleeding Details Anagrelide Tan-Shen Increased risk of bleeding Details Anagrelide Theophylline Accurbron® Increased theophylline serum concentrations and possible theophylline toxicity (nausea, vomiting, palpitations, seizures) Details Anagrelide Capsaicin Topical Aspercreme Warming® Increased risk of bleeding Details Anagrelide Capsaicin Transdermal Patch Aspercreme Warming® Patch Increased risk of bleeding Details Anagrelide Ibritumomab Injection Zevalin® An increased risk of bleeding and hemorrhage Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.