Anagrelide

434 interactions 313 cited references

Also sold as: Agrylin Agrylin®

About Anagrelide

Anagrelide is used to decrease the number of platelets (a type of blood cell that is needed to control bleeding) in the blood of patients who have a bone marrow disorder, in which the body makes too many of one or more types of blood cells, such as essential thrombocythemia (condition in which the body makes too many p… Read the full Anagrelide drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Piperaquine Bepridil Mesoridazine Abrocitinib Pimozide Levoketoconazole

15 Contraindicated 376 Major 41 Moderate 2 Minor

All (434) Contraindicated (15) Major (376) Moderate (41) Minor (2)

Major

Anagrelide Amitriptyline Elavil Increased risk of QT interval prolongation Details Anagrelide Sertraline Increased risk of bleeding and an increased risk of QT interval prolongation Details Anagrelide Buprenorphine Belbuca An increased risk of QT interval prolongation Details Anagrelide Relugolix Orgovyx Increased risk of QT interval prolongation Details Anagrelide Amisulpride Injection Barhemsys Increased risk of serious ventricular arrhythmias such as torsades de pointes Details Anagrelide Apixaban Eliquis Increased risk of bleeding and can cause serious, potentially fatal bleeding Details Anagrelide Arsenic Trioxide Trisenox Increased risk of QT interval prolongation Details Anagrelide Aripiprazole Injection Abilify An increased risk of QT interval prolongation Details Anagrelide Arsenic Trioxide Injection Trisenox Increased risk of QT interval prolongation Details Anagrelide Asenapine Transdermal Patch Secuado Increased risk of QT interval prolongation Details Anagrelide Aspirin Acuprin® An increased risk of bleeding Details Anagrelide Aspirin Rectal Aspirin An increased risk of bleeding Details Anagrelide Azithromycin AzaSite Increased risk of QT interval prolongation Details Anagrelide Betrixaban Bevyxxa® Increased risk of bleeding Details Anagrelide Alfuzosin UroXatral Increased risk of QT interval prolongation Details Anagrelide Abciximab Increased bleeding risk Details Anagrelide Aceclofenac An increased risk of bleeding Details Anagrelide Acemetacin An increased risk of bleeding Details Anagrelide Acenocoumarol Increased risk of bleeding Details Anagrelide Adagrasib Krazati An increased risk of QT interval prolongation, torsade de pointes, polymorphic ventricular tachycardia, other serious arrhythmias Details Anagrelide Alipogene Tiparvovec An increased risk of bleeding Details Anagrelide Amiodarone Nexterone An increased risk of QT interval prolongation and torsade de pointes Details Anagrelide Amisulpride Barhemsys Increased risk of serious ventricular arrhythmias such as torsades de pointes Details Anagrelide Amtolmetin Guacil An increased risk of bleeding Details Anagrelide Apomorphine Apokyn Increased risk of QT interval prolongation Details Anagrelide Ardeparin Increased risk of bleeding Details Anagrelide Argatroban Increased risk of bleeding Details Anagrelide Aripiprazole Abilify An increased risk of QT interval prolongation Details Anagrelide Aripiprazole Lauroxil Aristada An increased risk of QT interval prolongation Details Anagrelide Artemether An increased risk of QT interval prolongation Details Anagrelide Asenapine Saphris Increased risk of QT interval prolongation Details Anagrelide Astemizole Increased risk of QT interval prolongation Details Anagrelide Atazanavir Reyataz Increased risk of QT interval prolongation Details Anagrelide Balofloxacin Increased anagrelide exposure Details Anagrelide Bedaquiline Sirturo Increased risk of QT interval prolongation Details Anagrelide Bemiparin Increased risk of bleeding Details Anagrelide Besifloxacin Increased anagrelide exposure Details Anagrelide Bivalirudin Angiomax Increased risk of bleeding Details Anagrelide Bromfenac Bromsite An increased risk of bleeding Details Anagrelide Bufexamac An increased risk of bleeding Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.