Anagrelide

434 interactions 313 cited references
Also sold as: Agrylin Agrylin®
About Anagrelide

Anagrelide is used to decrease the number of platelets (a type of blood cell that is needed to control bleeding) in the blood of patients who have a bone marrow disorder, in which the body makes too many of one or more types of blood cells, such as essential thrombocythemia (condition in which the body makes too many p… Read the full Anagrelide drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Piperaquine Bepridil Mesoridazine Abrocitinib Pimozide Levoketoconazole
15 Contraindicated 376 Major 41 Moderate 2 Minor
All (434) Contraindicated (15) Major (376) Moderate (41) Minor (2)

Major

Anagrelide Ketorolac Injection Acular An increased risk of bleeding Details Anagrelide Ketorolac Nasal Spray Sprix An increased risk of bleeding Details Anagrelide Ketorolac Ophthalmic Acular An increased risk of bleeding Details Anagrelide Levofloxacin Injection Levaquin Increased anagrelide exposure and increased risk of QT interval prolongation Details Anagrelide Meloxicam Injection Alloxate An increased risk of bleeding Details Anagrelide Melphalan Injection Alkeran An increased risk of bleeding Details Anagrelide Metronidazole Injection Flagyl An increased risk of QT interval prolongation Details Anagrelide Metronidazole Topical MetroCream® An increased risk of QT interval prolongation Details Anagrelide Metronidazole Vaginal MetroGel® Vaginal An increased risk of QT interval prolongation Details Anagrelide Moxifloxacin Injection Avelox Increased anagrelide exposure and increased risk of QT interval prolongation Details Anagrelide Moxifloxacin Ophthalmic Moxeza® Increased anagrelide exposure and increased risk of QT interval prolongation Details Anagrelide Octreotide Injection Bynfezia Increased risk of QT interval prolongation Details Anagrelide Ofloxacin Ophthalmic Ocuflox Increased anagrelide exposure and increased risk of QT interval prolongation Details Anagrelide Ofloxacin Otic Floxin® Otic Increased anagrelide exposure and increased risk of QT interval prolongation Details Anagrelide Olodaterol Oral Inhalation Striverdi An increased risk of QT interval prolongation and an increased risk of ventricular arrhythmias Details Anagrelide Oxaliplatin Injection Eloxatin® Increased risk of QT-interval prolongation Details

Check another drug

Still have questions about this combination?

Every question gets a real answer from a licensed pharmacist — free, and usually within a day.

Ask the pharmacist
Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.