Anagrelide

434 interactions 313 cited references

Also sold as: Agrylin Agrylin®

About Anagrelide

Anagrelide is used to decrease the number of platelets (a type of blood cell that is needed to control bleeding) in the blood of patients who have a bone marrow disorder, in which the body makes too many of one or more types of blood cells, such as essential thrombocythemia (condition in which the body makes too many p… Read the full Anagrelide drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Piperaquine Bepridil Mesoridazine Abrocitinib Pimozide Levoketoconazole

15 Contraindicated 376 Major 41 Moderate 2 Minor

All (434) Contraindicated (15) Major (376) Moderate (41) Minor (2)

Major

Anagrelide Caplacizumab-Yhdp An increased risk of bleeding Details Anagrelide Celecoxib Celebrex An increased risk of bleeding Details Anagrelide Ceritinib Zykadia An increased risk of QT interval prolongation Details Anagrelide Certoparin Increased risk of bleeding Details Anagrelide Chloroquine Aralen® Increased risk of QT interval prolongation Details Anagrelide Chlorpromazine Increased risk of QT interval prolongation Details Anagrelide Choline Salicylate An increased risk of bleeding Details Anagrelide Cilostazol Pletal® Increased bleeding risk; additive vasodilation; increased risk of tachycardia, palpitations, and heart failure Details Anagrelide Ciprofloxacin Increased anagrelide exposure and increased risk of QT interval prolongation Details Anagrelide Citalopram Celexa An increased risk of QT interval prolongation and an increased risk of bleeding Details Anagrelide Clarithromycin Biaxin Increased risk of QT interval prolongation Details Anagrelide Clofazimine An increased risk of QT interval prolongation Details Anagrelide Clomipramine Anafranil Increased risk of QT interval prolongation Details Anagrelide Clonixin An increased risk of bleeding Details Anagrelide Clopidogrel Plavix Increased bleeding risk Details Anagrelide Clothiapine Increased risk of cardiac arrhythmias Details Anagrelide Clozapine Clozaril Increased risk of QT interval prolongation Details Anagrelide Crizotinib Xalkori An increased risk of QT interval prolongation Details Anagrelide Curcumin An increased risk of bleeding Details Anagrelide Cyclobenzaprine Amrix Increased risk of QT interval prolongation Details Anagrelide Dabigatran Etexilate Increased risk of bleeding Details Anagrelide Dabrafenib Tafinlar An increased risk of QT interval prolongation Details Anagrelide Dalteparin Fragmin Increased risk of bleeding Details Anagrelide Danaparoid Increased risk of bleeding Details Anagrelide Dasatinib Phyrago Increased risk of QT interval prolongation Details Anagrelide Degarelix Firmagon Increased risk of QT interval prolongation Details Anagrelide Delamanid Increased risk of QT interval prolongation Details Anagrelide Desflurane Suprane An increased risk of QT interval prolongation Details Anagrelide Desipramine Norpramin Increased risk of QT interval prolongation Details Anagrelide Desirudin Iprivask Increased risk of bleeding Details Anagrelide Desvenlafaxine Pristiq An increased risk of bleeding Details Anagrelide Deutetrabenazine Austedo An increased risk of QT interval prolongation Details Anagrelide Dexibuprofen An increased risk of bleeding Details Anagrelide Dexketoprofen An increased risk of bleeding Details Anagrelide Dexmedetomidine Dexased Increased risk of cardiac arrhythmias Details Anagrelide Diclofenac Aleve Arthritis Pain An increased risk of bleeding Details Anagrelide Diflunisal Dolobid An increased risk of bleeding Details Anagrelide Dipyridamole Permole® Increased bleeding risk Details Anagrelide Dipyrone An increased risk of bleeding Details Anagrelide Disopyramide Norpace Increased risk of QT interval prolongation Details

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