Anagrelide

434 interactions 313 cited references

Also sold as: Agrylin Agrylin®

About Anagrelide

Anagrelide is used to decrease the number of platelets (a type of blood cell that is needed to control bleeding) in the blood of patients who have a bone marrow disorder, in which the body makes too many of one or more types of blood cells, such as essential thrombocythemia (condition in which the body makes too many p… Read the full Anagrelide drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Piperaquine Bepridil Mesoridazine Abrocitinib Pimozide Levoketoconazole

15 Contraindicated 376 Major 41 Moderate 2 Minor

All (434) Contraindicated (15) Major (376) Moderate (41) Minor (2)

Major

Anagrelide Nelfinavir Viracept Increased risk of QT interval prolongation Details Anagrelide Nepafenac Ilevro An increased risk of bleeding Details Anagrelide Niflumic Acid An increased risk of bleeding Details Anagrelide Nilotinib Increased risk of QT interval prolongation Details Anagrelide Nimesulide An increased risk of bleeding Details Anagrelide Nimesulide Beta Cyclodextrin An increased risk of bleeding Details Anagrelide Norfloxacin Increased anagrelide exposure and increased risk of QT interval prolongation Details Anagrelide Octreotide Bynfezia Increased risk of QT interval prolongation Details Anagrelide Ofloxacin Floxin® Increased anagrelide exposure and increased risk of QT interval prolongation Details Anagrelide Olanzapine Increased risk of QT interval prolongation Details Anagrelide Olodaterol Striverdi An increased risk of QT interval prolongation and an increased risk of ventricular arrhythmias Details Anagrelide Ondansetron An increased risk of QT interval prolongation Details Anagrelide Osilodrostat Isturisa Increased risk of QT interval prolongation Details Anagrelide Osimertinib Tagrisso Increased risk of QT interval prolongation Details Anagrelide Oxaliplatin Increased risk of QT-interval prolongation Details Anagrelide Oxaprozin Coxanto An increased risk of bleeding Details Anagrelide Oxyphenbutazone An increased risk of bleeding Details Anagrelide Ozanimod Additive effects on heart rate Details Anagrelide Pacritinib Vonjo® An increased risk of QT interval prolongation Details Anagrelide Paliperidone Erzofri Increased risk of QT interval prolongation Details Anagrelide Panobinostat Farydak Increased risk of QT interval prolongation Details Anagrelide Parecoxib An increased risk of bleeding Details Anagrelide Parnaparin Increased risk of bleeding Details Anagrelide Paroxetine Paxil Increased risk of QT interval prolongation and an increased risk of bleeding Details Anagrelide Pasireotide Signifor Increased risk of QT interval prolongation Details Anagrelide Pazopanib Votrient An increased risk of QT-interval prolongation Details Anagrelide Pazufloxacin Increased anagrelide exposure Details Anagrelide Pefloxacin Increased anagrelide exposure Details Anagrelide Peginterferon Alfa-2B Increased plasma concentrations of anagrelide and its active metabolite and increased risk for toxicity including bleeding and QT-... Details Anagrelide Pentamidine NebuPent Increased risk of QT interval prolongation Details Anagrelide Perphenazine Increased risk of QT interval prolongation Details Anagrelide Phenindione Increased risk of bleeding Details Anagrelide Phenobarbital Fidoquel An increased risk of QT interval prolongation Details Anagrelide Phenprocoumon Increased risk of bleeding Details Anagrelide Phenylbutazone Equi-Phar An increased risk of bleeding Details Anagrelide Phenylpropanolamine Increased anagrelide exposure Details Anagrelide Piketoprofen An increased risk of bleeding Details Anagrelide Pimavanserin Nuplazid An increased risk of QT interval prolongation Details Anagrelide Pipamperone Increased risk of QT interval prolongation Details Anagrelide Piracetam Increased risk of bleeding Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.