Anagrelide

434 interactions 313 cited references
Also sold as: Agrylin Agrylin®
About Anagrelide

Anagrelide is used to decrease the number of platelets (a type of blood cell that is needed to control bleeding) in the blood of patients who have a bone marrow disorder, in which the body makes too many of one or more types of blood cells, such as essential thrombocythemia (condition in which the body makes too many p… Read the full Anagrelide drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Piperaquine Bepridil Mesoridazine Abrocitinib Pimozide Levoketoconazole
15 Contraindicated 376 Major 41 Moderate 2 Minor
All (434) Contraindicated (15) Major (376) Moderate (41) Minor (2)

Major

Anagrelide Piroxicam Feldene An increased risk of bleeding Details Anagrelide Pitolisant Wakix Increased risk of QT interval prolongation Details Anagrelide Pixantrone Increased anagrelide exposure Details Anagrelide Ponesimod Ponvory An increased risk of QT interval prolongation Details Anagrelide Posaconazole Noxafil Increased risk of QT interval prolongation Details Anagrelide Prasugrel Effient Increased bleeding risk Details Anagrelide Primidone Mysoline An increased risk of QT interval prolongation Details Anagrelide Probucol Increased risk of QT interval prolongation Details Anagrelide Procainamide Procan® Increased risk of QT interval prolongation Details Anagrelide Prochlorperazine Increased risk of QT interval prolongation Details Anagrelide Proglumetacin An increased risk of bleeding Details Anagrelide Promethazine Phenadoz Increased risk of QT interval prolongation Details Anagrelide Propafenone Rythmol Increased risk of QT interval prolongation Details Anagrelide Propyphenazone An increased risk of bleeding Details Anagrelide Proquazone An increased risk of bleeding Details Anagrelide Protein C Ceprotin Increased risk of bleeding Details Anagrelide Protriptyline Increased risk of QT interval prolongation Details Anagrelide Prulifloxacin Increased anagrelide exposure Details Anagrelide Quetiapine Seroquel An increased risk of QT interval prolongation Details Anagrelide Quinidine Cardioquin® Increased risk of QT interval prolongation Details Anagrelide Quinine Increased risk of QT interval prolongation Details Anagrelide Quizartinib Vanflyta An increased risk of QT interval prolongation Details Anagrelide Ranolazine Aspruzyo Increased risk of QT interval prolongation Details Anagrelide Remibrutinib Rhapsido An increased risk of bleeding Details Anagrelide Reviparin Increased risk of bleeding Details Anagrelide Revumenib Revuforj An increased risk of QT interval prolongation Details Anagrelide Ribociclib Kisqali An increased risk of QT interval prolongation Details Anagrelide Rilpivirine Edurant Increased risk of QT interval prolongation Details Anagrelide Risperidone Perseris Increased risk of QT interval prolongation Details Anagrelide Ritonavir Norvir Increased risk of QT interval prolongation Details Anagrelide Rivaroxaban Xarelto Increased risk of bleeding Details Anagrelide Rofecoxib An increased risk of bleeding Details Anagrelide Rufloxacin Increased anagrelide exposure Details Anagrelide Salicylic Acid An increased risk of bleeding Details Anagrelide Salsalate Disalcid An increased risk of bleeding Details Anagrelide Selpercatinib Retevmo Increased risk of QT interval prolongation Details Anagrelide Selumetinib Koselugo Increased risk of bleeding Details Anagrelide Sertindole Increased risk of QT interval prolongation Details Anagrelide Sevoflurane Petrem Increased risk of QT interval prolongation Details Anagrelide Siponimod Mayzent An increased risk of QT interval prolongation Details

Check another drug

Still have questions about this combination?

Every question gets a real answer from a licensed pharmacist — free, and usually within a day.

Ask the pharmacist
Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.