Anagrelide

434 interactions 313 cited references

Also sold as: Agrylin Agrylin®

About Anagrelide

Anagrelide is used to decrease the number of platelets (a type of blood cell that is needed to control bleeding) in the blood of patients who have a bone marrow disorder, in which the body makes too many of one or more types of blood cells, such as essential thrombocythemia (condition in which the body makes too many p… Read the full Anagrelide drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Piperaquine Bepridil Mesoridazine Abrocitinib Pimozide Levoketoconazole

15 Contraindicated 376 Major 41 Moderate 2 Minor

All (434) Contraindicated (15) Major (376) Moderate (41) Minor (2)

Major

Anagrelide Sodium Phosphate OsmoPrep Increased risk of QT interval prolongation Details Anagrelide Sodium Phosphate, Dibasic Increased risk of QT interval prolongation Details Anagrelide Sodium Phosphate, Monobasic Increased risk of QT interval prolongation Details Anagrelide Sodium Salicylate An increased risk of bleeding Details Anagrelide Solifenacin Vesicare Increased risk of QT interval prolongation Details Anagrelide Sorafenib Nexavar Increased risk of QT interval prolongation Details Anagrelide Sotalol Betapace Increased risk of QT interval prolongation Details Anagrelide Sulfinpyrazone Increased bleeding risk Details Anagrelide Sulindac Clinoril® An increased risk of bleeding Details Anagrelide Sulodexide Increased risk of bleeding Details Anagrelide Sulpiride An increased risk of QT interval prolongation Details Anagrelide Sunitinib Sutent Increased risk of QT interval prolongation Details Anagrelide Tacrolimus Astagraf Increased risk of QT interval prolongation Details Anagrelide Taletrectinib Ibtrozi Increased risk of QT interval prolongation and torsade de pointes Details Anagrelide Tamoxifen Nolvadex® Increased risk of QT interval prolongation Details Anagrelide Telaprevir Increased risk of QT interval prolongation Details Anagrelide Telavancin Vibativ Increased risk of QT interval prolongation Details Anagrelide Telithromycin Increased risk of QT interval prolongation Details Anagrelide Tenecteplase An increased risk of bleeding Details Anagrelide Tenoxicam An increased risk of bleeding Details Anagrelide Tetrabenazine Xenazine Increased risk of QT interval prolongation Details Anagrelide Thiabendazole Increased anagrelide exposure Details Anagrelide Tiaprofenic Acid An increased risk of bleeding Details Anagrelide Ticagrelor Brilinta Increased bleeding risk Details Anagrelide Ticlopidine Ticlid® Increased bleeding risk Details Anagrelide Tinzaparin Increased risk of bleeding Details Anagrelide Tirofiban Increased bleeding risk Details Anagrelide Tolfenamic Acid An increased risk of bleeding Details Anagrelide Tolmetin Tolectin 600 An increased risk of bleeding Details Anagrelide Tolterodine Detrol Increased risk of QT interval prolongation Details Anagrelide Toremifene Fareston Increased risk of QT interval prolongation Details Anagrelide Trazodone Raldesy Increased risk of QT interval prolongation and an increased risk of bleeding Details Anagrelide Treprostinil Orenitram Increased bleeding risk Details Anagrelide Triclabendazole Egaten An increased risk of QT interval prolongation Details Anagrelide Trimipramine Increased risk of QT interval prolongation Details Anagrelide Triptorelin Increased risk of QT interval prolongation Details Anagrelide Turmeric An increased risk of bleeding Details Anagrelide Valdecoxib An increased risk of bleeding Details Anagrelide Vandetanib Caprelsa Increased risk of QT-interval prolongation Details Anagrelide Vardenafil Levitra Increased risk of QT interval prolongation Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.