Anagrelide

434 interactions 313 cited references

Also sold as: Agrylin Agrylin®

About Anagrelide

Anagrelide is used to decrease the number of platelets (a type of blood cell that is needed to control bleeding) in the blood of patients who have a bone marrow disorder, in which the body makes too many of one or more types of blood cells, such as essential thrombocythemia (condition in which the body makes too many p… Read the full Anagrelide drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Piperaquine Bepridil Mesoridazine Abrocitinib Pimozide Levoketoconazole

15 Contraindicated 376 Major 41 Moderate 2 Minor

All (434) Contraindicated (15) Major (376) Moderate (41) Minor (2)

Major

Anagrelide Vemurafenib Zelboraf Increased risk of QT interval prolongation Details Anagrelide Venlafaxine An increased risk of bleeding and an increased risk of QT interval prolongation Details Anagrelide Vepdegestrant Veppanu An increased risk of QT interval prolongation and an increased risk of torsade de pointes, polymorphic ventricular tachycardia, ot... Details Anagrelide Vilanterol Increased risk of QT interval prolongation Details Anagrelide Vilazodone Viibryd An increased risk of bleeding Details Anagrelide Vinflunine Increased risk of QT-interval prolongation Details Anagrelide Voclosporin Lupkynis An increased risk of QT interval prolongation Details Anagrelide Voriconazole Vfend Increased risk of QT interval prolongation Details Anagrelide Vorinostat Zolinza Increased risk of QT interval prolongation Details Anagrelide Vortioxetine Trintellix An increased risk of bleeding Details Anagrelide Warfarin Coumadin An increased risk of bleeding Details Anagrelide Zanubrutinib Brukinsa An increased risk of bleeding Details Anagrelide Ziftomenib Komzifti An increased risk of QT interval prolongation and torsade de pointes Details Anagrelide Zileuton Zyflo Increased anagrelide exposure Details Anagrelide Zuclopenthixol An increased risk of QT interval prolongation Details Anagrelide Besifloxacin Ophthalmic Besivance Increased anagrelide exposure Details Anagrelide Bromfenac Ophthalmic Bromday® An increased risk of bleeding Details Anagrelide Caplacizumab-Yhdp Injection Cablivi An increased risk of bleeding Details Anagrelide Dabigatran Pradaxa® Increased risk of bleeding Details Anagrelide Dalteparin Injection Fragmin Increased risk of bleeding Details Anagrelide Degarelix Injection Firmagon Increased risk of QT interval prolongation Details Anagrelide Diclofenac Ophthalmic Voltaren® Eye Drops An increased risk of bleeding Details Anagrelide Diclofenac Topical (Actinic Keratosis) Pennsaid An increased risk of bleeding Details Anagrelide Diclofenac Topical (Arthritis Pain) Pennsaid® An increased risk of bleeding Details Anagrelide Diclofenac Transdermal Patch Flector An increased risk of bleeding Details Anagrelide Dolasetron Injection Anzemet Increased risk of QT interval prolongation Details Anagrelide Enoxaparin Injection Lovenox Increased risk of bleeding Details Anagrelide Eribulin Injection Halaven Increased risk of QT interval prolongation Details Anagrelide Famotidine Injection Calmicid Increased risk of QT interval prolongation Details Anagrelide Flurbiprofen Ophthalmic Ocufen An increased risk of bleeding Details Anagrelide Fondaparinux Injection Arixtra Increased risk of bleeding Details Anagrelide Foscarnet Injection Foscavir Increased risk of QT interval prolongation Details Anagrelide Gatifloxacin Ophthalmic Zymar® Increased anagrelide exposure and increased risk of QT interval prolongation Details Anagrelide Goserelin Implant Zoladex Increased risk of QT interval prolongation Details Anagrelide Granisetron Transdermal Patch Sancuso Increased risk of QT interval prolongation Details Anagrelide Granisetron Injection Granisol Increased risk of QT interval prolongation Details Anagrelide Heparin Injection Lipo-Hepin® Increased risk of bleeding Details Anagrelide Histrelin Implant Supprelin Increased risk of QT interval prolongation Details Anagrelide Inotuzumab Ozogamicin Injection Besponsa Increased risk of QT interval prolongation Details Anagrelide Ketoconazole Topical Extina® Foam An increased risk for QT interval prolongation Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.