Aripiprazole Injection

347 interactions 801 cited references

Also sold as: Abilify Abilify Maintena® Abilify® Aristad Initio® Aristada® Opipza

About Aripiprazole Injection

Aripiprazole extended-release injection (Abilify Maintena, Aristada, Aristada Initio) is used alone or in combination with other aripiprazole preparations to treat schizophrenia (a mental illness that causes disturbed or unusual thinking, loss of interest in life, and strong or inappropriate emotions). Aripiprazole ext… Read the full Aripiprazole Injection drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 12, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Mavorixafor Mesoridazine Metoclopramide Pimozide Piperaquine Posaconazole

20 Contraindicated 316 Major 11 Moderate

All (347) Contraindicated (20) Major (316) Moderate (11)

Major

Aripiprazole Injection Givinostat Duvyzat Increased risk of QT interval prolongation and torsade de pointes Details Aripiprazole Injection Glasdegib Daurismo Increased risk of QT interval prolongation Details Aripiprazole Injection Goserelin Increased risk of QT interval prolongation Details Aripiprazole Injection Granisetron An increased risk of QT interval prolongation Details Aripiprazole Injection Halazepam An increased risk of sedation and orthostatic hypotension Details Aripiprazole Injection Halofantrine An increased risk of QT interval prolongation Details Aripiprazole Injection Haloperidol An increased risk of QT interval prolongation and an increased risk of CNS depression Details Aripiprazole Injection Histrelin Supprelin Increased risk of QT interval prolongation Details Aripiprazole Injection Hydrocodone Hysingla Increased risk of respiratory and CNS depression Details Aripiprazole Injection Hydromorphone Dilaudid Increased risk of respiratory and CNS depression Details Aripiprazole Injection Hydroquinidine An increased risk of QT interval prolongation Details Aripiprazole Injection Hydroxychloroquine Plaquenil Increased risk of QT interval prolongation Details Aripiprazole Injection Hydroxyzine An increased risk of QT interval prolongation Details Aripiprazole Injection Ibutilide Corvert An increased risk of QT interval prolongation Details Aripiprazole Injection Idelalisib Zydelig Increased ARIPiprazole exposure Details Aripiprazole Injection Iloperidone Fanapt An increased risk of QT interval prolongation Details Aripiprazole Injection Imipramine An increased risk of QT interval prolongation Details Aripiprazole Injection Indinavir Increased ARIPiprazole exposure Details Aripiprazole Injection Inotuzumab Ozogamicin Besponsa Increased risk of QT-interval prolongation Details Aripiprazole Injection Insulin Aspart, Recombinant Fiasp Reduced blood glucose lowering effect of insulin Details Aripiprazole Injection Insulin Glargine, Recombinant Basaglar An increased risk of hypoglycemia Details Aripiprazole Injection Insulin Icodec-Abae Awiqli Reduced efficacy of insulin icodec-abae Details Aripiprazole Injection Isoflurane Fluriso An increased risk of QT interval prolongation and torsade de pointes Details Aripiprazole Injection Itraconazole Sporanox Increased ARIPiprazole exposure and an increased risk of QT interval prolongation Details Aripiprazole Injection Ivabradine Corlanor An increased risk of QT interval prolongation Details Aripiprazole Injection Ivosidenib Tibsovo Reduced ARIPiprazole or ARIPiprazole lauroxil (prodrug of ARIPiprazole) exposure and an increased risk of QT interval prolongation Details Aripiprazole Injection Ketamine Increased risk of respiratory and CNS depression Details Aripiprazole Injection Ketazolam An increased risk of sedation and orthostatic hypotension Details Aripiprazole Injection Kratom Increased CYP3A substrate exposure and an increased risk of CNS depression Details Aripiprazole Injection Lacosamide Motpoly An increased risk of CNS depression Details Aripiprazole Injection Lapatinib Tykerb An increased risk of QT interval prolongation Details Aripiprazole Injection Lefamulin Xenleta Increased risk of QT interval prolongation Details Aripiprazole Injection Lemborexant Dayvigo An increased risk of CNS depression and potential next-day somnolence Details Aripiprazole Injection Lenvatinib Lenvima Increased risk of QT-interval prolongation Details Aripiprazole Injection Letermovir Prevymis Increased CYP3A substrate exposure Details Aripiprazole Injection Leuprolide Eligard Increased risk of QT interval prolongation Details Aripiprazole Injection Levocetirizine Xyzal Increased risk of CNS depression Details Aripiprazole Injection Levodopa Inbrija An increased risk of CNS depression Details Aripiprazole Injection Levofloxacin Levaquin An increased risk of QT interval prolongation Details Aripiprazole Injection Levorphanol Xyvona An increased risk of respiratory and CNS depression Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.