Aspirin Rectal

385 interactions 2 explained in plain English 1,426 cited references
Also sold as: Aspirin
About Aspirin Rectal

Aspirin rectal is used to reduce fever and to relieve mild to moderate pain from headaches, menstrual periods, arthritis, toothaches, and muscle aches. Aspirin is in a group of medications called salicylates. It works by stopping the production of certain natural substances that cause fever, pain, swelling, and blood c… Read the full Aspirin Rectal drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 8, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

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6 Contraindicated 268 Major 107 Moderate 4 Minor
All (385) Contraindicated (6) Major (268) Moderate (107) Minor (4)

Moderate

Aspirin Rectal Omega-3-Acid Ethyl Esters Lovaza Increased risk of bleeding Details Aspirin Rectal Omega-3-Carboxylic Acids Increased risk of bleeding Details Aspirin Rectal Oxprenolol Reduced antihypertensive effect Details Aspirin Rectal Penbutolol Levatol® Reduced antihypertensive effect Details Aspirin Rectal Pentopril Decreased pentopril effectiveness Details Aspirin Rectal Pindolol Visken® Reduced antihypertensive effect Details Aspirin Rectal Pralatrexate Increased pralatrexate exposure Details Aspirin Rectal Pramlintide Symlin Increased risk of hypoglycemia Details Aspirin Rectal Propranolol Hemangeol Reduced antihypertensive effect Details Aspirin Rectal Quinidine Cardioquin® Prolonged bleeding times Details Aspirin Rectal Repaglinide Prandin® Increased risk of hypoglycemia Details Aspirin Rectal Skullcap Increased risk of bleeding Details Aspirin Rectal Sodium Bicarbonate Alka-Seltzer® Heartburn Decreased salicylate effectiveness Details Aspirin Rectal Sotalol Betapace Reduced antihypertensive effect Details Aspirin Rectal Sparsentan Filspari An increased risk of worsening of renal function Details Aspirin Rectal Streptokinase An increased risk of hemorrhagic complications Details Aspirin Rectal Sucroferric Oxyhydroxide Altered absorption of aspirin Details Aspirin Rectal Sulfinpyrazone A reduction in uricosuric effect and an increased risk of bleeding Details Aspirin Rectal Tamarind Increased salicylate toxicity Details Aspirin Rectal Tan-Shen Increased free salicylate serum concentration and decreased tan-shen (Danshen) concentration Details Aspirin Rectal Temocapril Decreased temocapril effectiveness Details Aspirin Rectal Tenecteplase An increased risk of bleeding Details Aspirin Rectal Tiludronate Skelid® Decreased tiludronate bioavailability Details Aspirin Rectal Timolol Betimol Reduced antihypertensive effect Details Aspirin Rectal Tolazamide Tolinase® Increased risk of hypoglycemia Details Aspirin Rectal Tolbutamide Orinase® Increased risk of hypoglycemia Details Aspirin Rectal Zofenopril Decreased zofenopril effectiveness Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.